Protein Alignment side-II and Igsf3

DIOPT Version :10

• Sequence 1: NP_001400995.1
• Gene: side-II / 3346206
• FlyBaseID: FBgn0259213
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: NP_001426444.1
• Gene: Igsf3 / 295325
• RGDID: 1307796
• Length: 1210
• Species: Rattus norvegicus
• Alignment Length: 739
• Identity: 141/739 - (19%)
• Similarity: 225/739 - (30%)
• Gaps: 294/739 - (39%)

  Fly   104 EQPRHW-----SAPE----------------VFGSRAK------FHFDSQPATLEIKDIKRHDQG 141
            ||...|     ||||                ::..|.:      .......|.|.|.|::..|.|
  Rat    52 EQNFQWSIYLPSAPEREVQIVSTVDSSFPYAIYTQRVRGGKIYVERIQGNSALLHITDLQARDAG 116

  Fly   142 IYRC---RVDFRTSQTQSFRFNLSVIILPEQPIIMDRWGRQLNGT---QLGPKQEGDDIVITCRV 200
            .|.|   ..|.|...:.|.:.||  :::|:          .|..|   |...|.|.|.:.::|.|
  Rat   117 EYECHTPNTDERYFGSYSAKMNL--VVIPD----------SLQTTAVPQTLHKVEQDPLELSCEV 169

  Fly   201 V-----------------GGRPQPQVRWLVNGLLVDNQNEHNSGDVIENRLLWPSVQRNDLNSVF 248
            .                 ||....:|..|....::.:.:|:              .||..|..|
  Rat   170 ATETLQHTHLSVSWLRQKGGENPVEVISLSRDFILHSSSEY--------------AQRQSLGEV- 219

  Fly   249 TCQALNTQLDKPKEKSFILDM-HLKPLVVKILEPPSSMIADRRYEVSCESSGSRPNAIITWYKGK 312
                   :|||....:|.|.: ||:|             :|:. |..||::....:...:||
  Rat   220 -------RLDKLGRSTFRLTIFHLQP-------------SDQG-EFYCEAAEWIQDPDGSWY--- 260

  Fly   313 RQLRRTKDDISKNSTRSELSFVPTTDDDGKSIT--------CRAENPNVNGLYLETMWKLNVVYP 369
            ...|:..:....|...::..|....:.|.:..|        |..|..|:...|....|..|
  Rat   261 AMTRKRSEGAVVNVQPTDKEFTVRLETDKRLHTVGEPVEFRCILEAQNIPDRYFAVSWAFN---- 321

  Fly   370 PLVTLRLGSTLTPDDI-------------------KEGDDVY--------------FECHVQSN- 400
                ..|.:|:.|:.:                   ||||.|:              :.|.|...
  Rat   322 ----SSLIATMGPNAVPVLNSEFAHREAKGQLKVAKEGDGVFVLKIYHLRQEDSGKYNCRVTERE 382

  Fly   401 ---------------------------------PQWRKLLWLHNGIHLEHNTSARVIRSNQSLVL 432
                                             ||..::  |..| |||.:.|..| .||.|:||
  Rat   383 KTVTGEFIDKESKRPKNIPIVVLPLTDNWVVKVPQQHQI--LPQG-HLESSMSVEV-ASNASVVL 443

  Fly   433 QKITKHYAGNYACSAINDEGETVSNQLPLRVKYTPMCKHAD----RVILIGASKDETVEVVCEIQ 493
            :....|    ::|:.     .||..   |:.:::.:.:..|    |..::...:|.||:
  Rat   444 EGEDLH----FSCTV-----RTVGR---LQARFSVIWQLVDRQNRRSNVMWLDRDGTVQ------ 490

  Fly   494 ADPPPRTFRWKFNNSG----ETLDVGSERFSVNGSRSILKYTPVTDQDYGTLSC----WAS---- 546
                |.:..|:.::.|    |.:...|....:..||.         :|.|...|    |..
  Rat   491 ----PGSSYWERSSYGGIQMEQVQPNSFSLGIFSSRK---------EDEGQYECHVTEWVRAVDG 542

  Fly   547 --NEVGTQQHPCLFQVVLAALPNAVSNCTVFNRT-----ELSVDIQCI--PGY------------ 590
              ..||.::...|..:.......||   |..:||     ..|.|:|||  |.|
  Rat   543 EWQIVGERRASTLVSITALETGFAV---TAISRTPGVTYSDSFDLQCIIKPHYPARVPVSVTWRF 604

  Fly   591 ----------------DGGLPQIFVLEMFSTRTGI--------TRFNLSNAEEA----------L 621
                            |||:........|.|||.|        .|.::|.|.:.          |
  Rat   605 QPVGTVEFHDLVTFTRDGGVQWGDKSSTFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAEL 669

  Fly   622 FSLENLDTLTSMMVQENNSLRLRI 645
            :.....:|.|.:..:.:|.|.:|:
  Rat   670 WRRNYNNTWTRLAERTSNLLEIRV 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side-II	NP_001400995.1	V-set	55..163	CDD:462230	21/88 (24%)
		Ig_3	190..254	CDD:464046	13/80 (16%)
		Ig	<292..366	CDD:472250	15/81 (19%)
		Ig strand B	292..295	CDD:409418	1/2 (50%)
		Ig strand C	305..309	CDD:409418	0/3 (0%)
		Ig strand E	329..333	CDD:409418	0/3 (0%)
		Ig strand F	343..348	CDD:409418	2/12 (17%)
		Ig strand G	359..362	CDD:409418	0/2 (0%)
		Ig	382..457	CDD:472250	26/141 (18%)
		Ig strand B	391..395	CDD:409405	1/17 (6%)
		Ig strand C	405..409	CDD:409405	0/3 (0%)
		Ig strand E	428..432	CDD:409405	1/3 (33%)
		Ig strand F	442..447	CDD:409405	1/4 (25%)
		Ig	486..554	CDD:409353	14/81 (17%)
		Ig strand B	486..490	CDD:409353	1/3 (33%)
		Ig strand C	500..504	CDD:409353	0/3 (0%)
		Ig strand E	526..530	CDD:409353	0/3 (0%)
		Ig strand F	540..545	CDD:409353	1/8 (13%)
Igsf3	NP_001426444.1	None