| Sequence 1: | NP_001014485.3 | Gene: | side-II / 3346206 | FlyBaseID: | FBgn0259213 | Length: | 1064 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055257.2 | Gene: | SIGLEC8 / 27181 | HGNCID: | 10877 | Length: | 499 | Species: | Homo sapiens |
| Alignment Length: | 645 | Identity: | 127/645 - (19%) |
|---|---|---|---|
| Similarity: | 199/645 - (30%) | Gaps: | 249/645 - (38%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MVLLLAMALLMPVTLARLHSTSGVGMSGGGSSMGPGGGGSGSGGISSKDSHVKTKDIDAV-EGKS 64
Fly 65 VSLPCPITEPLDNVYMVLWFRDNAGIPLYSFDVRDKESREQPRHWSAP--EVFG-SRAKFHF--- 123
Fly 124 ----DSQPATLEIKRHDQGIYRCRVDFRTSQTQSFRFNLS---------VIILPEQPIIMDRWGR 175
Fly 176 QLNGTQLGPKQEGDDIVITCRV----VGGRPQPQVRWLVNGLLVDNQNEHNSGDVIENRLLWPSV 236
Fly 237 QRNDLNSVFTCQALNTQLDKPKEKSFILDMHLKPLVVKILEPPSSMIADRRYEVSCESSGSRPNA 301
Fly 302 IITWYKGKRQLRRTKDDISKNSTRSELSFVPTTDDDGKSITCRAENPNVNGLYLETMWKLNVVYP 366
Fly 367 P--------------LVTLRLGSTLTPDDIKEGDDVYFECHVQSNPQWRKLLWLHNGIHLEHNTS 417
Fly 418 ARVIRSNQSLV-LQKITKHYAGNYACSAINDEG-ETVSNQLPLRVKYTPMCKHADRVIL-----I 475
Fly 476 GASK----------------------------DETVEVVCEIQ--ADPPPRTFRWKFNN------ 504
Fly 505 ------SGETLDVGSERFSVNGSRSILKYTP----VTDQDYGTLSCWASNEVGTQQHPCL 554 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| side-II | NP_001014485.3 | IG_like | 55..160 | CDD:214653 | 27/124 (22%) |
| Ig | 57..160 | CDD:299845 | 27/122 (22%) | ||
| Ig | 188..251 | CDD:299845 | 12/66 (18%) | ||
| Ig | 289..363 | CDD:299845 | 11/73 (15%) | ||
| IG_like | 289..351 | CDD:214653 | 9/61 (15%) | ||
| Ig_2 | 376..460 | CDD:290606 | 25/85 (29%) | ||
| IG_like | 383..454 | CDD:214653 | 21/72 (29%) | ||
| Ig | 470..548 | CDD:299845 | 21/128 (16%) | ||
| IG_like | 481..557 | CDD:214653 | 20/92 (22%) | ||
| SIGLEC8 | NP_055257.2 | Ig | 27..151 | CDD:299845 | 27/136 (20%) |
| Carbohydrate binding. /evidence=ECO:0000269|PubMed:27357658, ECO:0007744|PDB:2N7B | 72..75 | 0/2 (0%) | |||
| Carbohydrate binding. /evidence=ECO:0000269|PubMed:27357658, ECO:0007744|PDB:2N7B | 134..138 | 1/3 (33%) | |||
| Ig | 171..229 | CDD:299845 | 19/160 (12%) | ||
| IG_like | 269..344 | CDD:214653 | 24/83 (29%) | ||
| IGc2 | 275..335 | CDD:197706 | 20/65 (31%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 410..443 | 9/35 (26%) | |||
| ITIM motif | 445..450 | 0/4 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 451..470 | 3/18 (17%) | |||
| SLAM-like motif | 468..473 | 1/4 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 478..499 | 4/12 (33%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 0 | 0.000 | |||||