DRSC/TRiP Functional Genomics Resources

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Protein Alignment side-II and SIGLEC9

DIOPT Version :9

Sequence 1:NP_001014485.3 Gene:side-II / 3346206 FlyBaseID:FBgn0259213 Length:1064 Species:Drosophila melanogaster
Sequence 2:XP_006723209.1 Gene:SIGLEC9 / 27180 HGNCID:10878 Length:481 Species:Homo sapiens


Alignment Length:457 Identity:89/457 - (19%)
Similarity:135/457 - (29%) Gaps:211/457 - (46%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 EGKSVSLPCPITEPLDN------VYMVLWFRDNAGIPLYSFDVRDKESREQPRH--WSAPEVFGS 117
            ||..|.:||..:.|...      |....|||:.|     :.|.....:...|..  |..     :
Human    33 EGLCVHVPCSFSYPSHGWIYPGPVVHGYWFREGA-----NTDQDAPVATNNPARAVWEE-----T 87

  Fly   118 RAKFHFDSQP----ATLEI---KRHDQGIYRCRVDFRTSQ--TQSFRFNLSVIILPEQPIIMDRW 173
            |.:||....|    .||.|   :|.|.|.|..|::..:.:  .:..|.:::|..|..:|.|:   
Human    88 RDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFRMEKGSIKWNYKHHRLSVNVTALTHRPNIL--- 149

  Fly   174 GRQLNGT-QLGPKQEGDDIVITCRVVGGRPQPQVRWLVNGLLVDNQNEHNSGDVIENRLLWPSVQ 237
               :.|| :.|..|.     :||         .|.|                             
Human   150 ---IPGTLESGCPQN-----LTC---------SVPW----------------------------- 168

  Fly   238 RNDLNSVFTCQALNTQLDKPKEKSFILDMHLKPLVVKILEPPSSMIADRRYEVSCESSGSRPNAI 302
                                                                 :|| .|:.|  :
Human   169 -----------------------------------------------------ACE-QGTPP--M 177

  Fly   303 ITWYKGKRQLRRTKDDISKNSTRSE-LSFVPTTDDDGKSITCRAENPNVNGLYLETMWKLNVVYP 366
            |:|      :..:...:..::|||. |:.:|...|.|.|:||:...|..:....:|: .|||.||
Human   178 ISW------IGTSVSPLDPSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTV-HLNVSYP 235

  Fly   367 P--------------LVTLRLGSTLTPDDIKEGDDVYFEC---HVQSNP------QWR------- 401
            |              ...|..||:|:   :.||..:...|   .|.|||      .||       
Human   236 PQNLTMTVFQGDGTVSTVLGNGSSLS---LPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPS 297

  Fly   402 --------KLLWLHNGIHLEHNTSARVIRSNQSLVLQKITKHYAGNYACSAINDEGETVSNQLPL 458
                    :|.|:|             :|.             |..:.|.|.|..|   |.|:.|
Human   298 QPSNPGVLELPWVH-------------LRD-------------AAEFTCRAQNPLG---SQQVYL 333

  Fly   459 RV 460
            .|
Human   334 NV 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
side-IINP_001014485.3 IG_like 55..160 CDD:214653 27/115 (23%)
Ig 57..160 CDD:299845 27/115 (23%)
Ig 188..251 CDD:299845 4/62 (6%)
Ig 289..363 CDD:299845 19/74 (26%)
IG_like 289..351 CDD:214653 17/62 (27%)
Ig_2 376..460 CDD:290606 22/107 (21%)
IG_like 383..454 CDD:214653 18/94 (19%)
Ig 470..548 CDD:299845
IG_like 481..557 CDD:214653
SIGLEC9XP_006723209.1 Ig_Siglec_N 23..140 CDD:143189 27/116 (23%)
IG_like 26..>118 CDD:214653 24/94 (26%)
Ig 151..222 CDD:299845 25/175 (14%)
IG_like 258..336 CDD:214653 24/110 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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