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Protein Alignment side-II and CEACAM5

DIOPT Version :10

Sequence 1:	NP_001400995.1	Gene:	side-II / 3346206	FlyBaseID:	FBgn0259213	Length:	1067	Species:	Drosophila melanogaster
Sequence 2:	NP_004354.3	Gene:	CEACAM5 / 1048	HGNCID:	1817	Length:	702	Species:	Homo sapiens

Alignment Length:	725	Identity:	160/725 - (22%)
Similarity:	244/725 - (33%)	Gaps:	244/725 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 ISSKDSH-VKTKDIDAVEGKSVSLPC-PITEPLDNVYMVLWFRDNAGIPLYSFDVRDKESREQPR 107
            |||.:|. |:.||       :|:..| |.|:  |..|  ||:.:|..:|:            .||
Human   149 ISSNNSKPVEDKD-------AVAFTCEPETQ--DATY--LWWVNNQSLPV------------SPR 190

  Fly   108 HWSAPEVFGSRAKFHFDSQPATLEIKDIKRHDQGIYRCRVDFRTSQTQSFRFNLSVIILPEQPII 172
                         ....:...||.:.::.|:|...|:|......|..:|....|:|:..|:.|.|
Human   191 -------------LQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242

  Fly   173 MDRWGRQLNGTQLGPKQEGDDIVITCRVVGGRPQPQVRWLVNGLLVDNQNEHNSGDVIENRLLWP 237
                 ..||.:.    :.|:::.::|. ....|..|..|.|||....:..|          |..|
Human   243 -----SPLNTSY----RSGENLNLSCH-AASNPPAQYSWFVNGTFQQSTQE----------LFIP 287

  Fly   238 SVQRNDLNSVFTCQALNTQLDKPKEKSFILDMHLKPLVVKIL----EPPSSMIADRRYEVSCESS 298
            ::..|:..| :||||.|:            |..|....|..:    |||...|.
Human   288 NITVNNSGS-YTCQAHNS------------DTGLNRTTVTTITVYAEPPKPFIT----------- 328

  Fly   299 GSRPNAIITWYKGKRQLRRTKDDISKNSTRSELSFVPTTDDDGKSITCRAENPNVNGLYLETMWK 363
                                    |.||.       |..|:|..::||..|..|...|:    |.
Human   329 ------------------------SNNSN-------PVEDEDAVALTCEPEIQNTTYLW----WV 358

  Fly   364 LNVVYPPLVTLRLGS---TLT-----------------------------------PDD------ 384
            .|...|....|:|.:   |||                                   |||
Human   359 NNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTISPS 423

  Fly   385 ---IKEGDDVYFECHVQSNPQWRKLLWLHNGIHLEHNTSARVIRSNQSLVLQKITKHYAGNYACS 446
               .:.|.::...||..|||. .:..||.:|...:|         .|.|.:..||:..:|.|.|.
Human   424 YTYYRPGVNLSLSCHAASNPP-AQYSWLIDGNIQQH---------TQELFISNITEKNSGLYTCQ 478

  Fly   447 AINDEGE---------TVSNQLPLRVKYTPMCKHADRVILIGASKDETVEVVCEIQADPPPRTFR 502
            |.|....         |||.:||   |.:....::..|    ..|| .|...||.:|.  ..|:.
Human   479 ANNSASGHSRTTVKTITVSAELP---KPSISSNNSKPV----EDKD-AVAFTCEPEAQ--NTTYL 533

  Fly   503 WKFNNSGETLDVGSERFSVNGSRSILKYTPVTDQDYGTLSCWASNEV-GTQQHPCLFQVVLAALP 566
            |..|  |::|.|.......||:|::..:. ||..|.....|...|.| ..:..|....|:.....
Human   534 WWVN--GQSLPVSPRLQLSNGNRTLTLFN-VTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDT 595

  Fly   567 NAVSNCTVFNRTELSVDIQC------IPGYD---GGLPQIFVLEMFSTRTGITRFNLSNAEEALF 622
            ..:|.......:..::::.|      .|.|.   .|:||.....:|..:  ||..|  |...|.|
Human   596 PIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAK--ITPNN--NGTYACF 656

  Fly   623 SLENLDTLTSMMVQENNSLRLRIYSYNQKGRSAAYLLTDFIIGSTAYKTDDDVTLTLSPVIVGSV 687
             :.||.|      ..|||: ::..:.:..|.|.         |.:|..|            || :
Human   657 -VSNLAT------GRNNSI-VKSITVSASGTSP---------GLSAGAT------------VG-I 691

  Fly   688 LTIIIIGVAI 697
            :..:::|||:
Human   692 MIGVLVGVAL 701

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.