DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Unc-89 and HMCN1

DIOPT Version :9

Sequence 1:	NP_001097440.1	Gene:	Unc-89 / 3346201	FlyBaseID:	FBgn0053519	Length:	4218	Species:	Drosophila melanogaster
Sequence 2:	NP_114141.2	Gene:	HMCN1 / 83872	HGNCID:	19194	Length:	5635	Species:	Homo sapiens

Alignment Length:	3765	Identity:	810/3765 - (21%)
Similarity:	1303/3765 - (34%)	Gaps:	1073/3765 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   527 PAKVATPPPQPQVV---------TSPVKEVAPPPQPRAVASPAKE-------------------- 562
            |.| |:..|:|.|:         ||..|..|.......|.||..|
Human  1001 PCK-ASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV 1064

  Fly   563 -----VTP---------SQSEPVK----APSPIK---EVRKEVPPSASHSKEVEALVATEIRES- 605
                 |.|         ||.:||:    |...:.   ||:...||..:.:||.:.:.....|.:
Human  1065 QLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTF 1129

  Fly   606 -------LTETRSTVVESGQSSEIREEIV--VTEESSLEGKQVVALEREPSPCSIPKIQVYRPVE 661
                   :||||::  :||....:...|.  ||:...|.......::|.|...   |:||.:.|:
Human  1130 LPSGSMKITETRTS--DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHL---KVQVGQRVD 1189

  Fly   662 --CEN-----PVVTKHKPIELKDIVGYSESLRDGD---TAPAG------GSPGRQQGYSANITDH 710
              |..     ||:|..|        |.|..|.||:   :.|.|      .:|.....|:...|
Human  1190 IPCNAQGTPLPVITWSK--------GGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVAT-- 1244

  Fly   711 ASLTIWNNRLANIAG-DRSGANQHLQQSGPPPPPI----PPNFTRMPGFFQPLPLIAYETTIEIL 770
                       |||| |.:....|:|:    ||.:    ||                |.||.:..
Human  1245 -----------NIAGTDETEITLHVQE----PPTVEDLEPP----------------YNTTFQER 1278

  Fly   771 IVKARPPSPPP---PPPPTIK-----RVLVHTES----LEQKTQNFFEGIYDAASSDTSLRNAKQ 823
            :...|...|.|   .|.||||     |.|...|.    ||       :|.....:|.|...|.:.
Human  1279 VANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILE-------DGTLLVIASVTPYDNGEY 1336

  Fly   824 KIRSIKSTVLKSKDSTNYAQDTVQKAKARDFLHIFTPPVKK-----RPIYEIVEEPVNIF-ELEG 882
            ...::           |.|..|.:|..    |.:..|||.|     ..:..::.:..|:| |:||
Human  1337 ICVAV-----------NEAGTTERKYN----LKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEG 1386

  Fly   883 -------------DYTES----------IADDFR---EPSADFEARGQSVGGMDDYYSGY----- 916
                         ..|||          |...||   |.:..:..:..::.|....|...
Human  1387 TPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP 1451

  Fly   917 ---------SRASTRRYETKTRDYD-----RGTSY---------------DSTVERSQYG----- 947
                     :..|.    ...||..     :||.:               |..||....|
Human  1452 PTIIGTNFPNEVSV----VLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHL 1512

  Fly   948 ISSRRDRSSVDKVEARSSLLATGRTESRAASRAESRAES-RASYSVAESRAG----------IRS 1001
            .::||:    ||          ||.:...::.|..:|:. :.:..:..|..|          |.|
Human  1513 KNARRN----DK----------GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS 1563

  Fly  1002 SSRLQ-EDR--PLRSV----DKPVVVKMLKSVQVEPGETAH------------------------ 1035
            ..:|: |.|  |:.::    |...::...:::.::.|:..|
Human  1564 LIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAE 1628

  Fly  1036 --------------------------------FEIQFKDQPG-LVTWLKDNKPLEDRLADRITQT 1067
                                            .|.:....|. ::|||||..|:  :..|.|...
Human  1629 KSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPV--KANDNIRIE 1691

  Fly  1068 AAPMNSYRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAP---GHDETKTNTEPAFLVSL 1129
            |   ...:|:|.:..|.|.|.|...|.|.:....:..::.|...|   |.|||.     .|:|.:
Human  1692 A---GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS-----YFIVMV 1748

  Fly  1130 KDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGFYELVIADVQKTDA 1194
                   |.|......:.|.|.|.:.:.|| .::::..|..:|:     |...:||||..|.::.
Human  1749 -------NNLLELDCHVTGSPPPTIMWLKD-GQLIDERDGFKIL-----LNGRKLVIAQAQVSNT 1800

  Fly  1195 GTYSCKATNKHGEANCEAIAT-----TVEDKN-------PFGALSGQILPAG-EKPVFQWKRNGE 1246
            |.|.|.|.|..|:...|...|     |::...       .:..::.|.:..| ..|...|.::.:
Human  1801 GLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQ 1865

  Fly  1247 EFDPEE-RFKVLFGEDEDSLALVFQHVKP--EDAGIYTCVAQTSTGNISCSAELSVQGAIQTLNR 1308
            ..:..: ..|:      .|...|.|..|.  ||||.|||||..:.|......:|.|.
Human  1866 PVNTAQGNLKI------QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH-------- 1916

  Fly  1309 EPEKPTLVIEHREANASIGGSAILELQCK--GFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSL 1371
              |.|:|....:..|.::..|..::|:||  |.|.|.:.|..|..::.......|:   .....:
Human  1917 --EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQII 1976

  Fly  1372 VIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPPKIKKITD-ITCSAGETIKMEIEVEGFPQP 1435
            .|::....|||:|...|||..|..|...:|.|...|.|....: :.......:::|.|..|.|.|
Human  1977 DIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041

  Fly  1436 TVQVTNNGKDVTAESN-VKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCT 1499
            ::....:|..|::.|| :::.|.  |:     ::.:...::|..|.|:..|.|...:
Human  2042 SLTWLKDGSPVSSFSNGLQVLSG--GR-----ILALTSAQISDTGRYTCVAVNAAGE-------- 2091

  Fly  1500 VKSKPVIVKNFESEYIHGEKENVQMTV--------RIDAYPEAKLTWYHDETEIKITDSKYTVSS 1556
             |.:.:.::.:....|.||::||.:.:        :.||.|...|||..|...:.   .|..:|.
Human  2092 -KQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL---KKPGLSI 2152

  Fly  1557 DGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEF--THKLKNITVAEGDSNVEL 1619
            ..|...|||..|...|.|:||.:|||..|....:..:.|...|..  :.:|..:||.||:. :.|
Human  2153 SENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNL-ISL 2216

  Fly  1620 VVGVDAYPRPHAKWYIDGIEI-DEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLE 1683
            :......|.|:..|...|..: .:.....|.:..|...::.:.:.:.  ...|:|...|..|..:
Human  2217 LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSD--AALYSCVASNVAGTAK 2279

  Fly  1684 DNCVVTVNCKPKVKRGLKN---VEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRD 1745
            ....:.|..:|.:.....:   :.|..|||.:||.||...|...:.|.||||.:.:...::|..
Human  2280 KEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILD- 2343

  Fly  1746 TQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPE 1810
                |.:.|.|......|.|.|...|.|          ||.:|.:...|......::|.....||
Human  2344 ----EGHILQLKNIHVSDTGRYVCVAVN----------VAGMTDKKYDLSVHAPPSIIGNHRSPE 2394

  Fly  1811 EGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPITPDKHTAITVDGDHYKLEV 1875
            ..:|.|           ..||.|..|  |:|||.|...|:.||.|::......|...|...:|..
Human  2395 NISVVE-----------KNSVSLTCE--ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQ 2446

  Fly  1876 QSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKGDKVCEPVVFT 1940
            .:::  |||:|..||:|..||     |..:.|::....|.:.....|:|:||.:...|......|
Human  2447 TTME--DAGQYTCVVRNAAGE-----ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT 2504

  Fly  1941 ADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGE 2005
            .:|.|||...|||||:.|           |..:.::.....|.|...::..:|||.....:..|.
Human  2505 GNPVPEITWHKDGQPLQE-----------DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGH 2558

  Fly  2006 LVTSGWIDVLAKPEISGLND-------TKCL--PGDTICFEALVQANPKPKVSWTRGNENLCNHE 2061
            ...|..::|...|.|:|:..       |..|  |...:| ||  .:.|...::|.:....|.::.
Human  2559 KSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVC-EA--YSYPPATITWFKDGTPLESNR 2620

  Fly  2062 NCEVIADVDADKYRLVFQSVSPCED--GKYTITATNSEGRAAVDFNLAVLVEKPTFI-------- 2116
            |..::..      ....|.::..||  |:|:..|||..|.....:.:.|.:  |..|
Human  2621 NIRILPG------GRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYI--PPIINKGDLWGP 2677

  Fly  2117 -VQPESQSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPINYEAINKPGKDKLYAKEDTKKGTDQIE 2180
             :.|:...|.....::.:...:.:|..::.|:||.:|:                    |..|.:.
Human  2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL--------------------KSDDHVN 2722

  Fly  2181 -----SVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLSLAPSFVK------KLD-----NA 2229
                 ..|.||..:.:|.|.|||||:|..|..:..|.: .:.:.|||.|      .||     .|
Human  2723 IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDV-NIQVPPSFQKLWEIGNMLDTGRNGEA 2786

  Fly  2230 LDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKL 2294
            .||:...|:.|.|..:.:|.||:.|.|||..:..|:.:.|.  |.|.| |:|...:..|:|.|..
Human  2787 KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL--PGGRV-LQIPRAKVEDAGRYTC 2848

  Fly  2295 IISNPHGEKVALCAVAVKPEEMQPKFLKPITSQ-----TVVVGEPLKLEAQVTGFPAPEVKWYKD 2354
            :..|..||......|.|    :.|..:|...|.     ||:|.:...:|...:|.|||...|.||
Human  2849 VAVNEAGEDSLQYDVRV----LVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909

  Fly  2355 GMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEI-VPKESKPVFV 2418
            |..|.......|::  ||:|..|:: .|..|.|.|.|:..|..|..:....:.: ||..   |..
Human  2910 GQPLLEDDHHKFLS--NGRILQILN-TQITDIGRYVCVAENTAGSAKKYFNLNVHVPPS---VIG 2968

  Fly  2419 AELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGD 2483
            .:.::.:.:....:.:..:|.|.|.|.|.|..|...||.:.:.:.:    ....:|.|.:....|
Human  2969 PKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIV----PGGRTLQIIRAKVSD 3029

  Fly  2484 SGLYEVIAQNPEGSTASKAKL--YVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNP 2546
            .|.|..||.|..|.:..|..|  ||.|...:..:|       :|..||..||..:.|.....:.|
Human  3030 GGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE-------SLSVVNVREGTSVSLECESNAVP 3087

  Fly  2547 MPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSACNANVRKV 2611
            .|.:.|.|:|..:|.:..:.:..||:.  |.||.||.:|:|.|.|...|..|.|....:.|   |
Human  3088 PPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLN---V 3147

  Fly  2612 YKPPVFTQKISDQQQVFGNNAKIPVTV----SGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHML 2672
            |.||...   ..:::|.......|||:    :|:|.|.:.|....|.|..|:...::.......|
Human  3148 YVPPSIE---GPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKL 3209

  Fly  2673 IVNNCEKGDQGVYKCIASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKI-GDCDIYEGMVAKF 2736
            .:...:..|.|.|.|||||.|||......|.|        :..|.|...:| .|..:..|...:.
Human  3210 QIARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGENVEL 3266

  Fly  2737 TACATGYPEPEVEWFKNDQKLFPSDRFLIDIEPNGLLRLTIKNVTEYDVGRYSCRIFNPYG--DD 2799
            ...|.|.|.|.::|.|:.:.:...:...|.:..|| ..|.|......|.|:|:|...||.|  |.
Human  3267 VCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDR 3330

  Fly  2800 ICHAELFY-----DSLDSQQKPLEDQYTDFK-KYKKSGAPPPLSEGPIISRMTDRGLLLSW-NPS 2857
            |.:..::.     .:.|..:|.:....|... :.:.:|.|||               .::| ...
Human  3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP---------------QINWLKNG 3380

  Fly  2858 VPLTPRYPITYQIEMMDLPEGD-WRTLRTGVRSCA---CDIRNLEPFRDYRFRVRVENKFGVSDP 2918
            :||    |::..|.:  |..|. .|.:|..|...|   |...|         |..|:||.
Human  3381 LPL----PLSSHIRL--LAAGQVIRIVRAQVSDVAVYTCVASN---------RAGVDNKH----- 3425

  Fly  2919 SPYTQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPKDFDIERPPHDGLAQAPQFLLREQDISY 2983
                  |..::         :.||..|....|                            ::|:.
Human  3426 ------YNLQV---------FAPPNMDNSMGT----------------------------EEITV 3447

  Fly  2984 GVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQ--------------ATLFIN 3034
             :|..:|.:.....|.|.|.|                 ::.|:||              ..|.:.
Human  3448 -LKGSSTSMACITDGTPAPSM-----------------AWLRDGQPLGLDAHLTVSTHGMVLQLL 3494

  Fly  3035 KMLDRDVGWYEAVATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGRIEAKLV--GIPLPE 3097
            |....|.|.|..:|:||.||..:...|::.|.|......:...|....|..:|...:  |||.|:
Human  3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPK 3559

  Fly  3098 VHWFKDWKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTS--VTVHIEEN 3160
            :.|.||.:|:..:.:::......   ||.|..:.::|.|.|:..|.:.||.....  |.||:..|
Human  3560 MTWMKDGRPLPQTDQVQTLGGGE---VLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPN 3621

  Fly  3161 -----EDQYIYKTYGRHPYVRSKQLRYQDKYDI-----------GDELGRGTQGITYHAVERSSG 3209
                 |.:.|       ..:|::|:..:.|.|.           |:.|         .|..|
Human  3622 IAGTDEPRDI-------TVLRNRQVTLECKSDAVPPPVITWLRNGERL---------QATPR--- 3667

  Fly  3210 DNYAAKIMYGRPELRPFMLNELEMMNTFNHKNLIRPYDAYDTDRSVTLIMELAAGGELVRDNLLR 3274
                .:|:.|.   |...:|..::.:|.|:                          ..|..|:
Human  3668 ----VRILSGG---RYLQINNADLGDTANY--------------------------TCVASNI-- 3697

  Fly  3275 RDYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLISVVGGDIIKVSDFGLSRKINRHN-L 3338
                                          .|.|.::.:::|.....||.....|...:|:.. |
Human  3698 ------------------------------AGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVL 3732

  Fly  3339 STLDYGMPEFVSPEVV-NKEGVNFSHDMWTVGLITYVLLGGH-------NPFLGIDDRETLTKIR 3395
            ..:..|:|   :|.:. .|:|.              ||.|.|       |.||.|..
Human  3733 ECIAEGVP---TPRITWRKDGA--------------VLAGNHARYSILENGFLHIQS-------- 3772

  Fly  3396 EGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWFFMLDRPVYDHDYQIGTDRLR 3460
                       .|::|.||...           |....|                    |||
Human  3773 -----------AHVTDTGRYLC-----------MATNAA--------------------GTD--- 3792

  Fly  3461 NYYDHFRDWYANASCKNYFRRRRLSGCFQHPSKMVYPPGHVYTPENTPEPL-------PEPRIRA 3518
                                |||:......|..:...|.::....|....|       |:|.|..
Human  3793 --------------------RRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINW 3837

  Fly  3519 KREEVVSKYLHPDYELGLIQSESHYQYGPDTYLLQLRDVNFPVRLREYMKVAHRRSPSFALNDSV 3583
            ::.         .:.|.:.|:::.|:......|:.:                   |||  ::|:.
Human  3838 RKN---------GHLLNVDQNQNSYRLLSSGSLVII-------------------SPS--VDDTA 3872

  Fly  3584 DWSLPVIR---ERRRFTDI---MDEEIDDERTRSRISMYAAN----------------ESYSIRR 3626
            .:...|..   :.:|..|:   :...|.||.|...::.:|..                ....||.
Human  3873 TYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRL 3937

  Fly  3627 LRTELGPRLDEY----TEADAMIETQ------------------------REGYPPFFREKPQTI 3663
            |     ||.|.|    :.|..::.||                        ....||..:.:|..:
Human  3938 L-----PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSEL 3997

  Fly  3664 AITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVV 3728
            .:..|.|..:.|.|.|.|.|.:.|.|..:.:..|.|....:...|..|.|   |:..|.|.|..|
Human  3998 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISR---AVREDAGTYMCV 4059

  Fly  3729 ARNKVGQTVARCRIVVATLP-----------------------DAPDSPEIS------------- 3757
            |:|..|..:.:.::.|...|                       |....|:|:
Human  4060 AQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIR 4124

  Fly  3758 ---ANSGTEILLRWKQPRDDGH--------------STVLCYSLQYKLSNCDAWTTVADN 3800
               .:||: :.:.:.||.|.||              ||.|...:..::.:.:...||.:|
Human  4125 QRVLSSGS-LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNEN 4183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Unc-89	NP_001097440.1	RhoGEF	90..260	CDD:238091
		PH_unc89	275..388	CDD:270134
		Atrophin-1	<493..690	CDD:331285	54/232 (23%)
		TonB_N	502..>596	CDD:318287	27/118 (23%)
		I-set	1017..1108	CDD:333254	21/147 (14%)
		I-set	1123..1212	CDD:254352	23/88 (26%)
		I-set	<1236..1299	CDD:333254	18/65 (28%)
		I-set	1313..1403	CDD:254352	24/91 (26%)
		Ig_3	1406..1487	CDD:316449	17/82 (21%)
		I-set	1499..1595	CDD:254352	28/103 (27%)
		I-set	1599..1690	CDD:333254	17/93 (18%)
		I-set	1694..1786	CDD:254352	25/94 (27%)
		I-set	<1836..1903	CDD:333254	22/66 (33%)
		I-set	1922..2005	CDD:333254	22/82 (27%)
		I-set	2018..2108	CDD:333254	22/100 (22%)
		I-set	2113..2214	CDD:333254	24/114 (21%)
		I-set	2220..2302	CDD:254352	30/92 (33%)
		I-set	2318..2408	CDD:254352	28/94 (30%)
		I-set	2415..2506	CDD:254352	21/92 (23%)
		I-set	2519..2608	CDD:254352	26/88 (30%)
		I-set	2615..2696	CDD:254352	23/84 (27%)
		I-set	2717..2805	CDD:254352	24/90 (27%)
		FN3	2834..2925	CDD:238020	19/95 (20%)
		I-set	<2996..3063	CDD:333254	18/80 (23%)
		I-set	3067..3157	CDD:333254	23/93 (25%)
		PK_Unc-89_rpt1	3182..3440	CDD:271011	41/277 (15%)
		I-set	3654..3744	CDD:333254	24/89 (27%)
		FN3	3748..3840	CDD:238020	17/106 (16%)
		STKc_Unc-89_rpt2	3893..4151	CDD:271014
HMCN1	NP_114141.2	VWA_2	42..212	CDD:290253
		IG_like	440..512	CDD:214653
		Ig	451..510	CDD:299845
		IG	526..608	CDD:214652
		IGc2	533..593	CDD:197706
		I-set	612..696	CDD:254352
		Ig	626..696	CDD:299845
		IG	708..789	CDD:214652
		Ig	720..786	CDD:143165
		Ig	792..884	CDD:299845
		I-set	793..884	CDD:254352
		I-set	890..977	CDD:254352
		IGc2	903..967	CDD:197706
		Ig	980..1071	CDD:299845	14/70 (20%)
		IG	1086..1167	CDD:214652	20/82 (24%)
		Ig	1086..1167	CDD:299845	20/82 (24%)
		I-set	1171..1258	CDD:254352	26/110 (24%)
		Ig	1188..1256	CDD:299845	21/88 (24%)
		Ig	1261..1357	CDD:299845	29/133 (22%)
		IG_like	1276..1355	CDD:214653	22/100 (22%)
		IG_like	1369..1448	CDD:214653	14/78 (18%)
		IGc2	1382..1438	CDD:197706	10/55 (18%)
		I-set	1452..1542	CDD:254352	17/107 (16%)
		Ig	1460..1542	CDD:299845	17/99 (17%)
		IG	1556..1635	CDD:214652	9/78 (12%)
		Ig	1557..1635	CDD:299845	9/77 (12%)
		I-set	1647..1729	CDD:254352	19/86 (22%)
		Ig	1648..1725	CDD:299845	19/81 (23%)
		IGc2	1752..1812	CDD:197706	18/65 (28%)
		IG_like	1843..1915	CDD:214653	20/77 (26%)
		IGc2	1843..1905	CDD:197706	18/67 (27%)
		IG	1929..2008	CDD:214652	22/81 (27%)
		Ig	1934..2008	CDD:299845	21/76 (28%)
		Ig	2031..2092	CDD:299845	16/76 (21%)
		I-set	2111..2191	CDD:254352	24/82 (29%)
		IGc2	2119..2181	CDD:197706	21/64 (33%)
		I-set	2203..2286	CDD:254352	16/85 (19%)
		Ig	<2222..2277	CDD:299845	9/56 (16%)
		IG_like	2299..2380	CDD:214653	27/95 (28%)
		Ig	2299..2370	CDD:299845	24/85 (28%)
		I-set	2391..2474	CDD:254352	31/102 (30%)
		IGc2	2400..2464	CDD:197706	24/78 (31%)
		I-set	2478..2567	CDD:254352	25/99 (25%)
		IGc2	2493..2557	CDD:197706	18/74 (24%)
		I-set	2582..2663	CDD:254352	19/89 (21%)
		IGc2	2594..2653	CDD:197706	15/67 (22%)
		I-set	2681..2762	CDD:254352	22/101 (22%)
		IGc2	2689..2752	CDD:197706	18/82 (22%)
		IG_like	2789..2865	CDD:214653	25/78 (32%)
		IGc2	2791..2855	CDD:197706	21/66 (32%)
		I-set	2879..2960	CDD:254352	25/83 (30%)
		Ig	2879..2950	CDD:299845	24/73 (33%)
		Ig	2963..3054	CDD:299845	22/97 (23%)
		I-set	2970..3052	CDD:254352	20/85 (24%)
		I-set	3066..3147	CDD:254352	27/85 (32%)
		IGc2	3073..3137	CDD:197706	21/65 (32%)
		I-set	3151..3241	CDD:254352	25/92 (27%)
		IGc2	3167..3228	CDD:197706	17/60 (28%)
		Ig	3244..3338	CDD:299845	25/94 (27%)
		I-set	3252..3336	CDD:254352	23/84 (27%)
		I-set	3356..3430	CDD:254352	23/114 (20%)
		IGc2	3357..3420	CDD:197706	19/92 (21%)
		Ig	3433..3523	CDD:299845	25/135 (19%)
		IG_like	3443..3523	CDD:214653	21/97 (22%)
IG_like	3536..3616	CDD:214653	21/82 (26%)
IGc2	3543..3606	CDD:197706	17/65 (26%)
I-set	3628..3709	CDD:254352	19/164 (12%)
IGc2	3636..3699	CDD:197706	15/139 (11%)
I-set	3719..3800	CDD:254352	28/170 (16%)
Ig	3719..3795	CDD:299845	26/165 (16%)
I-set	3804..3893	CDD:254352	17/118 (14%)
Ig	3810..3883	CDD:299845	15/102 (15%)
Ig	3896..3984	CDD:299845	15/92 (16%)
IG_like	3903..3984	CDD:214653	12/85 (14%)
Ig	3987..4067	CDD:299845	25/82 (30%)
IG	3994..4075	CDD:214652	23/83 (28%)
I-set	4079..4165	CDD:254352	14/86 (16%)
IGc2	4093..4155	CDD:197706	10/62 (16%)
Ig	4168..4258	CDD:299845	3/16 (19%)
IG_like	4176..4256	CDD:214653	3/8 (38%)
I-set	4260..4345	CDD:254352
IGc2	4274..4335	CDD:197706
IG	4356..4435	CDD:214652
Ig	4356..4435	CDD:299845
I-set	4440..4526	CDD:254352
Ig	4443..4521	CDD:299845
TSP1	4533..4584	CDD:214559
TSP1	4589..4641	CDD:214559
TSP1	4646..4698	CDD:214559
TSP1	4703..4755	CDD:214559
TSP1	4760..4812	CDD:214559
TSP1	4817..4869	CDD:214559
G2F	4868..5092	CDD:214774
EGF_CA	5107..5146	CDD:214542
EGF_CA	5147..5190	CDD:284955
EGF_CA	5192..5228	CDD:214542
EGF_CA	5230..5263	CDD:238011
EGF_CA	5272..5313	CDD:284955
EGF_CA	5315..5354	CDD:214542
EGF_CA	5432..5471	CDD:214542
EGF_CA	5472..5508	CDD:214542
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4475
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100287
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2879
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.710