| Sequence 1: | NP_001097440.1 | Gene: | Unc-89 / 3346201 | FlyBaseID: | FBgn0053519 | Length: | 4218 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_065829.4 | Gene: | ALPK3 / 57538 | HGNCID: | 17574 | Length: | 1705 | Species: | Homo sapiens |
| Alignment Length: | 1786 | Identity: | 336/1786 - (18%) |
|---|---|---|---|
| Similarity: | 536/1786 - (30%) | Gaps: | 657/1786 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1073 SYRLDIKNCSETDAGTYTIRAQSASETT--TVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMI 1135
Fly 1136 ENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGF--YE---------LVIADV 1189
Fly 1190 QKTDAGTYSCKATNKHGEANCEA---IATTVEDK---NPFGALSGQILPAGEKPVFQWKRN---- 1244
Fly 1245 GE-----EFDPE--ERFKVLFG-----------EDEDSLALVFQHVKPEDA-----GIYTCVAQ- 1285
Fly 1286 --TSTGNIS---------------CSA-ELSVQGAIQTLN---------------REPEKPTLVI 1317
Fly 1318 EHREANASI------------GGSAILELQCK------------------------GFPKPAVQW 1346
Fly 1347 KHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPPKIKK 1411
Fly 1412 ITDITCSAGETIK----MEIEVEGF------------PQPT--------------VQVTNNGKDV 1446
Fly 1447 TAESNV-KISSSSIGKSLEKVVVEV-----------KEIKL-SQAGNYSIKATNDLSQTSEYWSC 1498
Fly 1499 TVKSKPVIVKNFESEYI---------HGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTV 1554
Fly 1555 SSDGNAYTLKITGATR-----------------VDAGKYTVKATNEHGSA--------TSSTQLL 1594
Fly 1595 IKCAPEFTHKLKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLI 1659
Fly 1660 MNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKPKVKRGLK-NVEVQEGKSFTLEVEVYSEPEA 1723
Fly 1724 KIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLT 1788
Fly 1789 SEALSLEQTV----TKTLIATTEEPEEGAVPEI-----------VHVDVFQQHS----------- 1827
Fly 1828 ---------------YESVPLKYEVIATGI-PKPEAIWYHDGKPITP-DKH--TAITVDGDHYKL 1873
Fly 1874 EVQSLDLVDAGEYKVVVQNKVG--EKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKGDKVCEP 1936
Fly 1937 VVFTADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLV---QYTCTLNILEAEIKDSGRYELK 1998
Fly 1999 VKNKYGELVTSGWIDVLAKP----EISGLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENLCN 2059
Fly 2060 HENCEVIADVDADKYRLVFQSVSPCED-GKYTITATNSEGRAAVDFNLAVLVEKPTFIVQPESQS 2123
Fly 2124 IHDYRPVSTKVLVHGVPLPTIEWFKDDKPINYEAINK--PGKDKLYAKEDTKKGTDQIESVLDIK 2186
Fly 2187 SFRENDVG-AYTCVATNEIGVTKA-PFKLAMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPL 2249
Fly 2250 PTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNP-HGEKVALCAVAVKP 2313
Fly 2314 EEM------------------------QPKFLKPITSQTVVVGEPLKLEAQVTGFPAPE------ 2348
Fly 2349 -----------VKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGG---- 2398
Fly 2399 ----------------EIEGVSKVEIVPKESKPVFVAELQDAS-----------SIE-------- 2428
Fly 2429 GFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQN 2493
Fly 2494 PEGSTASK--AKLYVAPKADETATEEAPQFV 2522 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Unc-89 | NP_001097440.1 | RhoGEF | 90..260 | CDD:238091 | |
| PH_unc89 | 275..388 | CDD:270134 | |||
| Atrophin-1 | <493..690 | CDD:331285 | |||
| TonB_N | 502..>596 | CDD:318287 | |||
| I-set | 1017..1108 | CDD:333254 | 10/36 (28%) | ||
| I-set | 1123..1212 | CDD:254352 | 29/99 (29%) | ||
| I-set | <1236..1299 | CDD:333254 | 21/108 (19%) | ||
| I-set | 1313..1403 | CDD:254352 | 18/125 (14%) | ||
| Ig_3 | 1406..1487 | CDD:316449 | 22/123 (18%) | ||
| I-set | 1499..1595 | CDD:254352 | 26/129 (20%) | ||
| I-set | 1599..1690 | CDD:333254 | 10/90 (11%) | ||
| I-set | 1694..1786 | CDD:254352 | 11/92 (12%) | ||
| I-set | <1836..1903 | CDD:333254 | 16/72 (22%) | ||
| I-set | 1922..2005 | CDD:333254 | 18/85 (21%) | ||
| I-set | 2018..2108 | CDD:333254 | 19/94 (20%) | ||
| I-set | 2113..2214 | CDD:333254 | 19/104 (18%) | ||
| I-set | 2220..2302 | CDD:254352 | 15/82 (18%) | ||
| I-set | 2318..2408 | CDD:254352 | 26/126 (21%) | ||
| I-set | 2415..2506 | CDD:254352 | 22/111 (20%) | ||
| I-set | 2519..2608 | CDD:254352 | 1/4 (25%) | ||
| I-set | 2615..2696 | CDD:254352 | |||
| I-set | 2717..2805 | CDD:254352 | |||
| FN3 | 2834..2925 | CDD:238020 | |||
| I-set | <2996..3063 | CDD:333254 | |||
| I-set | 3067..3157 | CDD:333254 | |||
| PK_Unc-89_rpt1 | 3182..3440 | CDD:271011 | |||
| I-set | 3654..3744 | CDD:333254 | |||
| FN3 | 3748..3840 | CDD:238020 | |||
| STKc_Unc-89_rpt2 | 3893..4151 | CDD:271014 | |||
| ALPK3 | NP_065829.4 | I-set | 77..169 | CDD:369462 | 29/103 (28%) |
| Atrophin-1 | 578..>950 | CDD:367360 | 84/492 (17%) | ||
| Ig | 1306..1359 | CDD:319273 | 19/55 (35%) | ||
| Alpha_kinase | 1383..1617 | CDD:355793 | 26/136 (19%) | ||
| PHA03378 | <1624..1705 | CDD:223065 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S7154 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.950 | |||||