| Sequence 1: | NP_001097440.1 | Gene: | Unc-89 / 3346201 | FlyBaseID: | FBgn0053519 | Length: | 4218 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001275658.1 | Gene: | DAPK1 / 1612 | HGNCID: | 2674 | Length: | 1430 | Species: | Homo sapiens |
| Alignment Length: | 803 | Identity: | 188/803 - (23%) |
|---|---|---|---|
| Similarity: | 306/803 - (38%) | Gaps: | 222/803 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3153 VTVHIEENEDQYIYKTYGRHPYVRSKQLRYQDKYDIGDELGRGTQGITYHAVERSSGDNYAAKIM 3217
Fly 3218 YGRPE-------LRPFMLNELEMMNTFNHKNLIRPYDAYDTDRSVTLIMELAAGGELVRDNLLRR 3275
Fly 3276 DYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLI--SVVGGDIIKVSDFGLSRKINRHNL 3338
Fly 3339 STLDYGMPEFVSPEVVNKEGVNFSHDMWTVGLITYVLLGGHNPFLGIDDRETLTKIREGRWDFKD 3403
Fly 3404 EIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWFFMLDRPVYDHDYQIGTDRLRN--YYDHF 3466
Fly 3467 RDWYANASCKNYFRR----RRLSGCFQHPSKMVYPPGHVYTPENTPEP----LPEPRIRAKREEV 3523
Fly 3524 VSKYLHPDYELGLIQSESHY------QYGPDTYLLQLRDVNFPVRLREYMKVAHRRSPSFALND- 3581
Fly 3582 ----SVDW--------SLPVIRERRRFTDIMDE----------------------------EIDD 3606
Fly 3607 ERTRSRISMYAANESYSIRRLRTELGPRLDEYTEADAMIETQREGYPPFFREKPQTIAITENQPS 3671
Fly 3672 HIHCFAV--GDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVG 3734
Fly 3735 QTVARCRI-VVATLPDA---PDSPEISANSGTEILLRWKQPRDDGHSTV---LCYSLQYKLSNCD 3792
Fly 3793 AWTTVADNIDHEFYLLHDLQPNTNY---QFRLASKNRI-----GWSEMGIPVSASTVGGDAPK-- 3847
Fly 3848 ------IHITKAMKHLQQLTENG 3864 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Unc-89 | NP_001097440.1 | RhoGEF | 90..260 | CDD:238091 | |
| PH_unc89 | 275..388 | CDD:270134 | |||
| Atrophin-1 | <493..690 | CDD:331285 | |||
| TonB_N | 502..>596 | CDD:318287 | |||
| I-set | 1017..1108 | CDD:333254 | |||
| I-set | 1123..1212 | CDD:254352 | |||
| I-set | <1236..1299 | CDD:333254 | |||
| I-set | 1313..1403 | CDD:254352 | |||
| Ig_3 | 1406..1487 | CDD:316449 | |||
| I-set | 1499..1595 | CDD:254352 | |||
| I-set | 1599..1690 | CDD:333254 | |||
| I-set | 1694..1786 | CDD:254352 | |||
| I-set | <1836..1903 | CDD:333254 | |||
| I-set | 1922..2005 | CDD:333254 | |||
| I-set | 2018..2108 | CDD:333254 | |||
| I-set | 2113..2214 | CDD:333254 | |||
| I-set | 2220..2302 | CDD:254352 | |||
| I-set | 2318..2408 | CDD:254352 | |||
| I-set | 2415..2506 | CDD:254352 | |||
| I-set | 2519..2608 | CDD:254352 | |||
| I-set | 2615..2696 | CDD:254352 | |||
| I-set | 2717..2805 | CDD:254352 | |||
| FN3 | 2834..2925 | CDD:238020 | |||
| I-set | <2996..3063 | CDD:333254 | |||
| I-set | 3067..3157 | CDD:333254 | 2/3 (67%) | ||
| PK_Unc-89_rpt1 | 3182..3440 | CDD:271011 | 94/266 (35%) | ||
| I-set | 3654..3744 | CDD:333254 | 16/92 (17%) | ||
| FN3 | 3748..3840 | CDD:238020 | 18/105 (17%) | ||
| STKc_Unc-89_rpt2 | 3893..4151 | CDD:271014 | |||
| DAPK1 | NP_001275658.1 | STKc_DAPK1 | 7..275 | CDD:271096 | 99/296 (33%) |
| Calmodulin-binding | 267..334 | 18/78 (23%) | |||
| Autoinhibitory domain. /evidence=ECO:0000250 | 292..301 | 1/8 (13%) | |||
| ANK | 373..497 | CDD:238125 | 16/128 (13%) | ||
| ANK repeat | 378..409 | CDD:293786 | 4/35 (11%) | ||
| ANK 1 | 378..407 | 4/33 (12%) | |||
| ANK 2 | 411..440 | 4/28 (14%) | |||
| ANK repeat | 412..442 | CDD:293786 | 5/29 (17%) | ||
| ANK | 439..564 | CDD:238125 | 30/180 (17%) | ||
| ANK repeat | 444..475 | CDD:293786 | 1/30 (3%) | ||
| ANK 3 | 444..473 | 0/28 (0%) | |||
| ANK repeat | 477..508 | CDD:293786 | 5/39 (13%) | ||
| ANK 4 | 477..506 | 5/37 (14%) | |||
| ANK | 505..629 | CDD:238125 | 36/209 (17%) | ||
| ANK repeat | 510..541 | CDD:293786 | 9/56 (16%) | ||
| ANK 5 | 510..539 | 8/34 (24%) | |||
| Ank_2 | <515..768 | CDD:330894 | 41/229 (18%) | ||
| ANK repeat | 543..574 | CDD:293786 | 12/51 (24%) | ||
| ANK 6 | 543..572 | 11/49 (22%) | |||
| ANK repeat | 576..607 | CDD:293786 | 8/60 (13%) | ||
| ANK 7 | 576..605 | 8/58 (14%) | |||
| ANK repeat | 609..638 | CDD:293786 | 8/28 (29%) | ||
| ANK 8 | 609..638 | 8/28 (29%) | |||
| ANK 9 | 875..904 | ||||
| ANK 10 | 1162..1196 | ||||
| Death_DAPK1 | 1308..1393 | CDD:260052 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0032 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||