| Sequence 1: | NP_001097440.1 | Gene: | Obsc / 3346201 | FlyBaseID: | FBgn0053519 | Length: | 4218 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_061508151.1 | Gene: | Obsc / 1276165 | VectorBaseID: | AGAMI1_006292 | Length: | 5440 | Species: | Anopheles gambiae |
| Alignment Length: | 5463 | Identity: | 2086/5463 - (38%) |
|---|---|---|---|
| Similarity: | 2819/5463 - (51%) | Gaps: | 1380/5463 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 6 DIVFVSRDYQAQSLATDEISVSRGDLVELI----------------------------------- 35
Fly 36 -------------------------SSKASEKSRCFVRMFDSGDSPKEGWVPIDILEFNPTMSSS 75
Fly 76 NGKESGDAEFRKLTILRELVETEEEFSRDLLHVVEKYIKGIDKP--VVPRSVRDNKDIIFCNFLQ 138
Fly 139 IAEFHNNVLKEGLKCYSNQPNMVAKTFLRLERDFDKHVVYCQNEPLAQDYLGSSPDAKKYFQELS 203
Fly 204 KQLGDDKSLAEHLKLPIQRINDYQLLFKDFIKYSLSLKENVKDLERALELMLSVPSRAYDNRFLS 268
Fly 269 SIEGCRGNIYKLGRLLLHAWCNVVDKEGKAHDRYCFLFKSRILVTKVRKISENRSVFILQNIVKL 333
Fly 334 PLCNIELKADEKQIHLSLKAPEANSFLPIDIKPHGPEAHLTWFNEISSHINQDVTLQEHNADDLK 398
Fly 399 VDASQIASESELILHLPQRAEAHDPNLSVRPSDVAENYFLSK----------------------- 440
Fly 441 ----------------------------------------------------------------- 440
Fly 441 ----------------------------------------------------------------- 440
Fly 441 ------------ETKERL----------------------------------------------- 446
Fly 447 ------QHEQQ------------------------------------------------------ 451
Fly 452 -----------ELLKLEQ----------------------------------------------- 458
Fly 459 ---EAIE---------------------------------------------------------- 462
Fly 463 ----------------------------LYKKQQS-----------------------------S 470
Fly 471 KSVSSKTESV----EITSSQVKSS----------------------------------------- 490
Fly 491 -----------------------------SEVRKVVSP----------PPPPQAQV---KEVTPV 513
Fly 514 KV------------------VSSPPP--------------------------------------- 521
Fly 522 ----------PKEITPAKVATP--------------PPQPQVVTSPVKEVAP-----PPQPRAVA 557
Fly 558 SPAKEVTPSQS----EPVKAPSPIKEVR-----------------------------KEVPPS-- 587
Fly 588 ------------------------------ASHSKEVEALVATEIRES-----------LTETRS 611
Fly 612 TVVESGQSSEIREEIVVTEESSLEGKQVVALEREPS-----------------------PCSIPK 653
Fly 654 IQVYRPVE--CENPVVTKHKPIE--LKDIVGYSESL--------RDGDTAPAGGS---------- 696
Fly 697 ----------------------------------------------------------------- 696
Fly 697 ---------------PGRQQGYSANITDHASLTIWNNRLANI-AGDRSGANQHLQQSGP------ 739
Fly 740 ---------------------------------PPPPIPPNFTRMPGFFQPLPLIAYETTIEILI 771
Fly 772 VKARPPSPPPPPPPTIKRVLVHTESLEQKTQNFFEGIYDAASSDTSLRNAKQKIRSIKSTVLKSK 836
Fly 837 DSTNYAQDTVQKAKARDFLHIFTPPVK-----KRPIYE---IVEEPV----------NIFELEGD 883
Fly 884 YTESIADDFREPSADFEARGQSVGGMDDYY-SGYSRASTRRYETKTRDYDRGTSYDSTVERSQYG 947
Fly 948 ISSRRDRSSVDKVEARSSLLATGRTESRAASRAESRAESRASYSVAESRAGIRSSSRLQEDRPLR 1012
Fly 1013 SVDKPVVVKMLKSVQVEPGETAHFEIQFKDQPGLVTWLKDNKPLEDRLADRITQTAAPMNSYRLD 1077
Fly 1078 IKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKT---------NTEPAFLVSLKDAE 1133
Fly 1134 MIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGFYELVIADVQKTDAGTYS 1198
Fly 1199 CKATNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQWKRNGEEFDPEERFKVLFGEDED 1263
Fly 1264 SLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAIQTLNREPEKPTLVIEHREANASIGG 1328
Fly 1329 SAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELG 1393
Fly 1394 QDESSINLVVKAPPKIKKITDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSS 1458
Fly 1459 IGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSKPVIVKNFESEYIHGEKENVQ 1523
Fly 1524 MTVRIDAYPEAKLTWYHDETEIKITDSKYTV--SSDGNAYTLKITGATRVDAGKYTVKATNEHGS 1586
Fly 1587 ATSSTQLLIKCAPEFTHKLKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVE 1651
Fly 1652 EGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVE 1716
Fly 1717 VYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTS- 1780
Fly 1781 ----------------------------------TCKVAVLTSE--------------------- 1790
Fly 1791 ---------------------------ALSLEQ-----------------------TVTKTLI-- 1803
Fly 1804 ----------------------------------------------------------------- 1803
Fly 1804 ----------------------------------------------------------------- 1803
Fly 1804 ----------------------------ATTEEPEEGAV--------------PEIVHVDVFQQH 1826
Fly 1827 SYESVPLKYEVIATGIPKPEAIWYHDGKPITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQ 1891
Fly 1892 NKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPV 1956
Fly 1957 VETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEIS 2021
Fly 2022 GLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQSVSPCED 2086
Fly 2087 GKYTITATNSEGRAAVDFNLAVLVEKPTFIVQPESQSIHDYRPVSTKVLVHGVPLPTIEWFKDDK 2151
Fly 2152 PINYEAINKPGKD---KLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKL 2213
Fly 2214 AMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVK 2278
Fly 2279 LEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEAQVTG 2343
Fly 2344 FPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEI 2408
Fly 2409 VPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSS 2473
Fly 2474 LIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVL 2538
Fly 2539 SAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSA 2603
Fly 2604 CNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGD 2668
Fly 2669 HHMLIVNNCEKGDQGVYKCIASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMV 2733
Fly 2734 AKFTACATGYPEPEVEWFKNDQKLFPSDRFLIDIEPNGLLRLTIKNVTEYDVGRYSCRIFNPYGD 2798
Fly 2799 DICHAELFYDSLDSQQKPLEDQYTDFKKYKKS------GAPP-PLSEGPIISRMTDRGLLLSWNP 2856
Fly 2857 SVPLTPRYPITYQIEMMDLPEGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPY 2921
Fly 2922 TQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPKDFDIERPPHDGLAQAPQFLLREQDISYGVK 2986
Fly 2987 DHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNE 3051
Fly 3052 HGEARQRVRLEIAEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKIS 3116
Fly 3117 SYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQYIYKTYGRHPYVRSKQLR 3181
Fly 3182 YQDKYDIGDELGRGTQGITYHAVERSSGDNYAAKIMYGRPELRPFMLNELEMMNTFNHKNLIRPY 3246
Fly 3247 DAYDTDRSVTLIMELAAGGELVRDNLLRRDYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKD 3311
Fly 3312 LLISVVGGDIIKVSDFGLSRKINRHNLSTLDYGMPEFVSPEVVNKEGVNFSHDMWTVGLITYVLL 3376
Fly 3377 GGHNPFLGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWFF 3441
Fly 3442 MLDRPVYDHDYQIGTDRLRNYYDHFRDWYANASCKNYFRRRRLSGCFQHPSKMVYPPGHVYTPEN 3506
Fly 3507 TPEPLPE---PRIRAKREEVVSKYLHPDYELGLIQSESHYQYGPDTYLLQLRDVNFPVRLREYMK 3568
Fly 3569 VAHRRSPSFALNDSVDWSLPVIRERRRFTDIMDEEIDDERTRSRISMYAANESYSI-RRLRTELG 3632
Fly 3633 PRLDEYTEADAMIETQREGYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTES 3697
Fly 3698 KRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGT 3762
Fly 3763 EILLRWKQPRDDGHSTVLCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRI 3827
Fly 3828 GWSEMGIPV-SASTVGGDAPKIHITKAMKHLQQLTENGHQVVPEEERVHTDYHCEREPPNWVTDS 3891
Fly 3892 SVSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDE-NEDNVVAEFDNFKTLRHERIPA 3955
Fly 3956 LFSAYKPLNVPIAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQ 4020
Fly 4021 PDNVVMASVRSIQVKLVDFGSAKKVNKLGMKVTPCGSLDFQPPEMINDEPIFPQSDIWSLGALTY 4085
Fly 4086 LLLSGCSPFRGADEYETKQNISFVRYRFENLFKEVTPEATRFIMLLFKRHPTKRPYTEDCLEHRW 4150
Fly 4151 LMSSDYMVRKRERAIFLGSRLKTFCDEYHDLKNASATSSKVLNTVAGGPTPTQLLRSNSIQEELL 4215
Fly 4216 TTF 4218 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Obsc | NP_001097440.1 | RhoGEF | 90..260 | CDD:238091 | 109/171 (64%) |
| PH_unc89 | 275..388 | CDD:270134 | 48/112 (43%) | ||
| Not5 | <477..>652 | CDD:444384 | 66/446 (15%) | ||
| Ig | 1017..1108 | CDD:472250 | 40/90 (44%) | ||
| Ig strand B | 1034..1038 | CDD:409353 | 2/3 (67%) | ||
| Ig strand C | 1046..1050 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 1074..1078 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 1088..1093 | CDD:409353 | 2/4 (50%) | ||
| Ig strand G | 1101..1104 | CDD:409353 | 0/2 (0%) | ||
| I-set | 1123..1212 | CDD:400151 | 47/88 (53%) | ||
| Ig strand B | 1140..1144 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 1153..1157 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 1182..1186 | CDD:409353 | 3/3 (100%) | ||
| Ig strand F | 1196..1201 | CDD:409353 | 3/4 (75%) | ||
| Ig strand G | 1209..1212 | CDD:409353 | 0/2 (0%) | ||
| Ig | <1236..1299 | CDD:472250 | 48/62 (77%) | ||
| Ig strand C | 1238..1242 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 1259..1269 | CDD:409353 | 6/9 (67%) | ||
| Ig strand F | 1279..1284 | CDD:409353 | 3/4 (75%) | ||
| Ig strand G | 1292..1295 | CDD:409353 | 1/2 (50%) | ||
| I-set | 1313..1403 | CDD:400151 | 50/89 (56%) | ||
| Ig strand B | 1330..1334 | CDD:409353 | 2/3 (67%) | ||
| Ig strand C | 1343..1347 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 1369..1373 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 1383..1388 | CDD:409353 | 2/4 (50%) | ||
| Ig strand G | 1396..1399 | CDD:409353 | 0/2 (0%) | ||
| Ig_3 | 1406..1487 | CDD:464046 | 26/80 (33%) | ||
| I-set | 1499..1595 | CDD:400151 | 32/97 (33%) | ||
| Ig strand B | 1522..1526 | CDD:409353 | 0/3 (0%) | ||
| Ig strand C | 1535..1539 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 1561..1565 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 1575..1580 | CDD:409353 | 2/4 (50%) | ||
| Ig strand G | 1588..1591 | CDD:409353 | 1/2 (50%) | ||
| Ig | 1599..1690 | CDD:472250 | 33/90 (37%) | ||
| Ig strand B | 1617..1621 | CDD:409353 | 2/3 (67%) | ||
| Ig strand C | 1630..1634 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 1656..1660 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 1670..1675 | CDD:409353 | 1/4 (25%) | ||
| Ig strand G | 1683..1686 | CDD:409353 | 1/2 (50%) | ||
| I-set | 1694..1786 | CDD:400151 | 43/126 (34%) | ||
| Ig strand B | 1711..1715 | CDD:409353 | 2/3 (67%) | ||
| Ig strand C | 1724..1728 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 1752..1756 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 1766..1771 | CDD:409353 | 2/4 (50%) | ||
| Ig strand G | 1779..1782 | CDD:409353 | 1/37 (3%) | ||
| Ig | <1836..1903 | CDD:472250 | 28/66 (42%) | ||
| Ig strand C | 1846..1850 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 1871..1875 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 1885..1890 | CDD:409353 | 2/4 (50%) | ||
| Ig | 1922..2005 | CDD:472250 | 32/82 (39%) | ||
| Ig strand B | 1933..1937 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 1946..1950 | CDD:409353 | 2/3 (67%) | ||
| Ig strand E | 1971..1984 | CDD:409353 | 5/12 (42%) | ||
| Ig strand F | 1994..1999 | CDD:409353 | 1/4 (25%) | ||
| Ig | 2018..2108 | CDD:472250 | 43/89 (48%) | ||
| Ig strand B | 2034..2038 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 2047..2051 | CDD:409353 | 2/3 (67%) | ||
| Ig strand E | 2074..2078 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 2088..2093 | CDD:409353 | 2/4 (50%) | ||
| Ig strand G | 2101..2104 | CDD:409353 | 0/2 (0%) | ||
| Ig | 2113..2214 | CDD:472250 | 34/103 (33%) | ||
| Ig strand B | 2130..2134 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 2143..2147 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 2176..2185 | CDD:409353 | 2/8 (25%) | ||
| Ig strand F | 2195..2200 | CDD:409353 | 2/4 (50%) | ||
| I-set | 2220..2302 | CDD:400151 | 36/81 (44%) | ||
| Ig strand B | 2238..2242 | CDD:409353 | 2/3 (67%) | ||
| Ig strand C | 2251..2255 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 2277..2281 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 2291..2296 | CDD:409353 | 3/4 (75%) | ||
| Ig strand G | 2304..2307 | CDD:409353 | 0/2 (0%) | ||
| I-set | 2318..2408 | CDD:400151 | 40/89 (45%) | ||
| Ig strand B | 2335..2339 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 2348..2352 | CDD:409353 | 2/3 (67%) | ||
| Ig strand E | 2374..2378 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 2388..2393 | CDD:409353 | 2/4 (50%) | ||
| Ig | 2415..2506 | CDD:472250 | 35/90 (39%) | ||
| Ig strand B | 2432..2436 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 2445..2449 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 2472..2476 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 2486..2491 | CDD:409353 | 1/4 (25%) | ||
| Ig strand G | 2499..2502 | CDD:409353 | 1/2 (50%) | ||
| I-set | 2519..2608 | CDD:400151 | 52/88 (59%) | ||
| Ig strand B | 2536..2540 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 2549..2553 | CDD:409353 | 3/3 (100%) | ||
| Ig strand E | 2574..2578 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 2588..2593 | CDD:409353 | 2/4 (50%) | ||
| I-set | 2615..2696 | CDD:400151 | 33/80 (41%) | ||
| Ig strand B | 2632..2636 | CDD:409353 | 2/3 (67%) | ||
| Ig strand C | 2645..2649 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 2670..2674 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 2684..2689 | CDD:409353 | 2/4 (50%) | ||
| Ig strand G | 2697..2700 | CDD:409353 | 0/2 (0%) | ||
| I-set | 2717..2805 | CDD:400151 | 41/87 (47%) | ||
| Ig strand B | 2734..2738 | CDD:409353 | 2/3 (67%) | ||
| Ig strand C | 2747..2751 | CDD:409353 | 2/3 (67%) | ||
| Ig strand E | 2773..2777 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 2787..2792 | CDD:409353 | 4/4 (100%) | ||
| Ig strand G | 2800..2803 | CDD:409353 | 2/2 (100%) | ||
| FN3 | 2834..2925 | CDD:238020 | 58/91 (64%) | ||
| Ig | <2996..3063 | CDD:472250 | 52/66 (79%) | ||
| Ig strand C | 3003..3007 | CDD:409353 | 2/3 (67%) | ||
| Ig strand E | 3029..3033 | CDD:409353 | 3/3 (100%) | ||
| Ig strand F | 3043..3048 | CDD:409353 | 3/4 (75%) | ||
| Ig strand G | 3056..3059 | CDD:409353 | 2/2 (100%) | ||
| Ig | 3067..3157 | CDD:472250 | 56/89 (63%) | ||
| Ig strand B | 3085..3088 | CDD:409353 | 1/2 (50%) | ||
| Ig strand C | 3097..3101 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 3123..3127 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 3137..3142 | CDD:409353 | 4/4 (100%) | ||
| Ig strand G | 3150..3153 | CDD:409353 | 1/2 (50%) | ||
| PK_Unc-89_rpt1 | 3182..3440 | CDD:271011 | 164/257 (64%) | ||
| Ig | 3654..3744 | CDD:472250 | 59/89 (66%) | ||
| Ig strand B | 3671..3675 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 3684..3688 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 3710..3714 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 3724..3729 | CDD:409353 | 3/4 (75%) | ||
| Ig strand G | 3737..3740 | CDD:409353 | 2/2 (100%) | ||
| FN3 | 3748..3840 | CDD:238020 | 55/92 (60%) | ||
| STKc_Unc-89_rpt2 | 3893..4151 | CDD:271014 | 172/258 (67%) | ||
| Obsc | XP_061508151.1 | None | |||