Sequence 1: | NP_001097440.1 | Gene: | Unc-89 / 3346201 | FlyBaseID: | FBgn0053519 | Length: | 4218 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | XP_012819807.1 | Gene: | trio / 100170157 | XenbaseID: | XB-GENE-922516 | Length: | 3085 | Species: | Xenopus tropicalis |
Alignment Length: | 2151 | Identity: | 413/2151 - (19%) |
---|---|---|---|
Similarity: | 720/2151 - (33%) | Gaps: | 730/2151 - (33%) |
- Green bases have known domain annotations that are detailed below.
Fly 7 IVFVSRDYQAQSLATDEISVSRGDLVELISSKASEKSRCFVRMFDSGDSPKEGWVPIDILEFNPT 71
Fly 72 MSSSNGKESGDAEF-----------RKLTILRELVETEEEFSRDLLHVVEKYI----KGIDKPVV 121
Fly 122 PRSVRDNKDIIFCNFLQIAEFHNNVLKEGLKCYSNQPNMVAKTFLRLERDFDKHVVYCQNEPLAQ 186
Fly 187 DYLGSSPDAKKYFQELSKQLGDDKSLAEHLKLPIQRINDYQLLFKDFIKYSLSLKENVKDLERAL 251
Fly 252 ELMLSVPSRAYDNRFLSSIEGCRGNIYKLGRLLLHAWCNVVDKE---GKAHDRYCFLFKSRILVT 313
Fly 314 KVRKISENRSVFILQNIVKLPLCNIELKADEKQIHLS----------LKAPEANSFLPIDIKPHG 368
Fly 369 PEAHLTWFNEISSHINQDVTLQEHNADDLKVDASQIASESELILHLPQRAEAHDPNLSVRPSDVA 433
Fly 434 ENYFLSKETKERLQHEQQELLKLEQEAIELYKKQQSSKSVSSKTESVEITSSQVKSSSEVRKVV- 497
Fly 498 -------SPPPPPQAQVKEVTP----------VKVVSSPPPPKEITPAKV--------------- 530
Fly 531 -------------ATPPP-----QPQVV---TSPVKEVAPPPQP-----RAVASPAKEVTPSQSE 569
Fly 570 PVKAPSPIKEVRKEVPPSASHSKEVEALVATEIRESLTETRSTVVESGQSSEIREEIVVTEESSL 634
Fly 635 EGKQVVALEREPSPCSIPKIQVYRPVECENPVVTKHKPIELKDIVGYSESLRDGDTAPAGGSPGR 699
Fly 700 QQGYSANITDHASLTIWNNRLANIAGDRSGANQHLQQSGPPPPPIPPNFTRMPGFFQPLPLIAYE 764
Fly 765 -----TTIEILIVKARPPSPPPPPP----PTIKRVLVHTESLEQKTQNFFEGIYDAAS-----SD 815
Fly 816 TSLRNAKQKIRSI---KSTVLKSKDSTNYA-QDTVQKAKARDFLHIFTPPVKKRPIYEIVEEPVN 876
Fly 877 IFELEGDYTESIADDFREPSADFEARGQS---VGGMDDYYSGYSRASTRRYETKTRDYDRGTSYD 938
Fly 939 STVERSQYGISSRRDRSSVDKVEARSSLLATGRTESRAASRAESRAESRASYSVAESRAGIRSSS 1003
Fly 1004 RLQEDRPLRSVDKPVVVKMLKSVQVEPGETAHFEIQFKDQPGLVTWLKDNKPLEDRLADRITQT- 1067
Fly 1068 --AAPMN---SYRLDIKNCSETDAGTYTIRA-------QSASETTTV-----SAQLAVGQAPGHD 1115
Fly 1116 -----ETKTNTEPAFLVSLKDAEMI----ENTLFRF-MVKIIGDPKPRVKFYKDEKEILETNDRI 1170
Fly 1171 QII-----------------RDKDYL----------GFYELVIADVQKT---------------- 1192
Fly 1193 -----DAGTYSCKATNKHGEANCEA-----------IATTVEDKNPF---GALSGQI-------L 1231
Fly 1232 PAGEKPVFQWKRNGEEFDPEERFKVLF-----GEDEDSLAL----VFQHVKPEDAGIYTCV--AQ 1285
Fly 1286 TS-TGNISCSAELSVQGAIQ----------------TLN------REPEKPTLVIEHREANASIG 1327
Fly 1328 GSAILELQCKGFPKPAVQWKHDGEVIQVD-DRHKFMYEDEESMSLV------------------- 1372
Fly 1373 -----IKNVDTV------------DAGVYTIEAINELGQDESSINLVVKAPPKIKKITDITCSAG 1420
Fly 1421 ETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKA 1485
Fly 1486 TNDLSQTSEYWSCTVKSKPVIVKNFESEYIHGEK---------------ENVQMTVRIDAYPEAK 1535
Fly 1536 LTWYHDETEIKITDSKYTVS-SDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLI---- 1595
Fly 1596 -------------------------------KCAPEFTHKL-----------------KNITVAE 1612
Fly 1613 GDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEE-GN--DFKL--IMNQVATNMQGNYT 1672
Fly 1673 CKIMNDYGKLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYED 1737
Fly 1738 ARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSEALS-----LEQT 1797
Fly 1798 VTKTLI 1803 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Unc-89 | NP_001097440.1 | RhoGEF | 90..260 | CDD:238091 | 57/173 (33%) |
PH_unc89 | 275..388 | CDD:270134 | 33/125 (26%) | ||
Atrophin-1 | <493..690 | CDD:331285 | 33/255 (13%) | ||
TonB_N | 502..>596 | CDD:318287 | 22/144 (15%) | ||
I-set | 1017..1108 | CDD:333254 | 18/108 (17%) | ||
I-set | 1123..1212 | CDD:254352 | 23/141 (16%) | ||
I-set | <1236..1299 | CDD:333254 | 14/74 (19%) | ||
I-set | 1313..1403 | CDD:254352 | 21/126 (17%) | ||
Ig_3 | 1406..1487 | CDD:316449 | 14/80 (18%) | ||
I-set | 1499..1595 | CDD:254352 | 33/111 (30%) | ||
I-set | 1599..1690 | CDD:333254 | 16/112 (14%) | ||
I-set | 1694..1786 | CDD:254352 | 16/91 (18%) | ||
I-set | <1836..1903 | CDD:333254 | |||
I-set | 1922..2005 | CDD:333254 | |||
I-set | 2018..2108 | CDD:333254 | |||
I-set | 2113..2214 | CDD:333254 | |||
I-set | 2220..2302 | CDD:254352 | |||
I-set | 2318..2408 | CDD:254352 | |||
I-set | 2415..2506 | CDD:254352 | |||
I-set | 2519..2608 | CDD:254352 | |||
I-set | 2615..2696 | CDD:254352 | |||
I-set | 2717..2805 | CDD:254352 | |||
FN3 | 2834..2925 | CDD:238020 | |||
I-set | <2996..3063 | CDD:333254 | |||
I-set | 3067..3157 | CDD:333254 | |||
PK_Unc-89_rpt1 | 3182..3440 | CDD:271011 | |||
I-set | 3654..3744 | CDD:333254 | |||
FN3 | 3748..3840 | CDD:238020 | |||
STKc_Unc-89_rpt2 | 3893..4151 | CDD:271014 | |||
trio | XP_012819807.1 | SEC14 | 64..199 | CDD:214706 | |
SPEC | 215..440 | CDD:238103 | |||
SPEC | 336..561 | CDD:238103 | |||
SPEC | 562..778 | CDD:238103 | |||
SPEC | 782..1009 | CDD:238103 | |||
SPEC | 903..1132 | CDD:238103 | |||
SPEC | 1138..1238 | CDD:197544 | 5/21 (24%) | ||
RhoGEF | 1289..1459 | CDD:238091 | 58/176 (33%) | ||
PH1_Kalirin_Trio_like | 1466..1588 | CDD:270060 | 35/131 (27%) | ||
SH3_Kalirin_1 | 1654..1713 | CDD:212786 | 8/58 (14%) | ||
SH3-RhoG_link | 1710..1967 | CDD:293215 | 61/368 (17%) | ||
RhoGEF | 1965..2138 | CDD:238091 | 45/288 (16%) | ||
PH2_Kalirin_Trio_p63RhoGEF | 2143..2281 | CDD:270061 | 23/137 (17%) | ||
SH3_Kalirin_2 | 2543..2601 | CDD:212787 | 15/74 (20%) | ||
I-set | 2673..2764 | CDD:254352 | 28/90 (31%) | ||
Ig | 2687..2764 | CDD:299845 | 28/76 (37%) | ||
STKc_Trio_C | 2776..3038 | CDD:271015 | 43/259 (17%) | ||
S_TKc | 2784..3038 | CDD:214567 | 43/251 (17%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |