DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33506 and U3-55K

DIOPT Version :9

Sequence 1:	NP_001014528.1	Gene:	CG33506 / 3346177	FlyBaseID:	FBgn0053506	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001014529.1	Gene:	U3-55K / 3346176	FlyBaseID:	FBgn0053505	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	180	Identity:	37/180 - (20%)
Similarity:	66/180 - (36%)	Gaps:	42/180 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 INWSSPSGKLLEEAIVLNEDEQIFGLSKAVLQMQTH--RVLLNSIF---------PSVSFLMVYT 193
            :.|.:.:||:||::.||:..|:    .:...:.::|  .:.|:|..         |.:......|
  Fly   185 LKWCTETGKVLEKSDVLSHREE----PETGKKRRSHVISICLSSDMKYLALAEGGPHIQIWCPQT 245

  Fly   194 MGHYLNLR------LDLFARHGSVRFVLYSILGLFGLGLWS----------FMKDYNQVSTDAEI 242
            |.|...|:      ..|..|.|:  ..|||......:.:||          |.......|.||..
  Fly   246 MKHIKTLKGHRDSVAGLVFRKGT--HDLYSAAKDRSVKIWSLDEMAYVESLFGHQTAVTSIDALS 308

  Fly   243 DQRLATMGP--------QLVAAGASFYDKHLKKNIALRELIGNDVYTALG 284
            .:|..|.|.        ::.......|:.| |.:|...:.|.::.:.:.|
  Fly   309 RERAITAGGSDCSLRIWKITEESQLIYNGH-KDSIECVKYINDEHFVSGG 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33506	NP_001014528.1	None
U3-55K	NP_001014529.1	Upf2	55..>125	CDD:281974
		WD40	<150..484	CDD:225201	37/180 (21%)
		WD40	156..416	CDD:295369	37/180 (21%)
		WD40 repeat	163..203	CDD:293791	7/17 (41%)
		WD40 repeat	218..254	CDD:293791	7/35 (20%)
		WD40 repeat	259..295	CDD:293791	8/37 (22%)
		WD40 repeat	302..336	CDD:293791	6/33 (18%)
		WD40 repeat	342..379	CDD:293791	3/16 (19%)
		WD40 repeat	391..431	CDD:293791
		WD40 repeat	436..461	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0299
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900