DRSC/TRiP Functional Genomics Resources

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Protein Alignment U3-55K and Tango4

DIOPT Version :10

Sequence 1:NP_001014529.1 Gene:U3-55K / 3346176 FlyBaseID:FBgn0053505 Length:484 Species:Drosophila melanogaster
Sequence 2:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster


Alignment Length:428 Identity:95/428 - (22%)
Similarity:167/428 - (39%) Gaps:87/428 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 FSSDEGEEETPQ-DKRLRLAKQ----------YLSEIEK-QEAERAE------DRELAQSVEQRL 126
            |.|::|  ..|: |:||...::          .|.::.| .||.:|.      |:.||  :....
  Fly    26 FVSNQG--NLPEIDERLEKLRRSIKAKDGYGLVLDKVAKIGEARKASGAQTPGDKTLA--ITDGS 86

  Fly   127 QTEYLDSVGKLRRNIAGSLKACESSRILKHKLHHTPICALALSPDGKFLYTGAKSQFLLKWCTET 191
            .|:.....|.|.:..||: :..|.:..|....|.:.:.|...:.:......||            
  Fly    87 ATDAASGAGSLVKYNAGA-RPAEKTAPLVTGTHTSLVRASLANSNADMSANGA------------ 138

  Fly   192 GKVLEKSDVLSH-----REEPETGKK------RRSHVIS--------ICLSSDMKYLALAEGGPH 237
                    :.||     ::.|...|.      :.|.|||        |.:....::.|...|...
  Fly   139 --------IASHLQLIPKKAPSIPKPKWHAPWKLSRVISGHLGWVRCIAVEPGNEWFATGAGDRV 195

  Fly   238 IQIWCPQTMKHIKTLKGHRDSVAGLVFRKGTHDLYSAAKDRSVKIWSLDEMAYVESLFGHQTAVT 302
            |:||...:.|...:|.||..:|.|:........|:|..:||.||.|.|:....:....||.:||.
  Fly   196 IKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVY 260

  Fly   303 SIDALSRERAITAGGSDCSLRIWKI-TEESQLIYNGHKDSI-ECVKYINDEHFVSGGMDGAIGLW 365
            |:........:...|.|.:.|||.: |:.:.....||.::: ..|....:...::|..|..:.||
  Fly   261 SLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLW 325

  Fly   366 SALKKKPICTTQLAHGVGENGVANWITAI-AVVVNTDL--VATGSCDGCVRLWQTNPNARKMNLI 427
            .....|.:||           :.|...:: ::|::..|  .|:.|.|. ::.|:. |..:   .:
  Fly   326 DLAAGKSVCT-----------LTNHKKSVRSIVLHPSLYMFASASPDN-IKQWRC-PEGK---FV 374

  Fly   428 QSIS-IAGFINGLAFNADGSKLFVATGQEHRLGRW-WR 463
            |:|| ....:|.:|.|::|  :.|:.|....:..| ||
  Fly   375 QNISGHTSIVNCMAANSEG--VLVSGGDNGTMFFWDWR 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
U3-55KNP_001014529.1 WD40 156..416 CDD:475233 59/283 (21%)
WD40 repeat 163..203 CDD:293791 3/39 (8%)
WD40 repeat 218..254 CDD:293791 10/43 (23%)
WD40 repeat 259..295 CDD:293791 10/35 (29%)
WD40 repeat 302..336 CDD:293791 7/34 (21%)
WD40 repeat 342..379 CDD:293791 8/37 (22%)
WD40 repeat 391..431 CDD:293791 8/42 (19%)
YncE <420..477 CDD:442618 12/46 (26%)
WD40 repeat 436..461 CDD:293791 6/24 (25%)
Tango4NP_572778.1 WD40 164..458 CDD:238121 65/265 (25%)
WD40 repeat 177..212 CDD:293791 8/34 (24%)
WD40 repeat 218..254 CDD:293791 9/35 (26%)
WD40 repeat 259..295 CDD:293791 8/35 (23%)
WD40 repeat 302..337 CDD:293791 8/45 (18%)
WD40 repeat 343..378 CDD:293791 8/39 (21%)
WD40 repeat 386..426 CDD:293791 8/27 (30%)
WD40 repeat 433..457 CDD:293791
Blue background indicates that the domain is not in the aligned region.

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