Protein Alignment btsz and SYT15

DIOPT Version :10

• Sequence 1: NP_001247109.1
• Gene: btsz / 3346167
• FlyBaseID: FBgn0266756
• Length: 3734
• Species: Drosophila melanogaster
• Sequence 2: XP_016872239.1
• Gene: SYT15 / 83849
• HGNCID: 17167
• Length: 428
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 83/323 - (25%)
• Similarity: 127/323 - (39%)
• Gaps: 74/323 - (22%)

  Fly  3398 GQVEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDKSKAGKRKTKVKKHTLNP 3462
            |::.|:::|..:...|.|.:::.:.|   .|......|.||:|||||:.:..:.|||.|  |.||
Human   156 GRLWFSVEYEQEAERLLVGLIKAQHL---QAPSETCSPLVKLYLLPDERRFLQSKTKRK--TSNP 215

  Fly  3463 IFDETMRFHTPISSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLF--DNPQSQWYLLQERS- 3524
            .|||...|.....::..|.|..:|:|.|...::..||:|...|:....  |..:..|..|:..|
Human   216 QFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAESL 280

  Fly  3525 EPFDEVATYRGDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIKSVASKSERTSKGGQ 3589
            ||..|.    ||:...|.|       :.:.||
Human   281 EPPSEF----GDLQFCLSY-------NDYLSR--------------------------------- 301

  Fly  3590 LHVLVKEAKHLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRTLHPSWNYTFVYEDVSLEEL 3654
            |.|:|..||.|...:..|....|.|..|:........:||..|..:::|.:|.||.:: ....||
Human   302 LTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFK-ADATEL 365

  Fly  3655 SERALELTV---WDHDRLASNEFVGGIRFSLGTGRSYGRQV--EWMDATGKELSLWQNMLDRP 3712
            ...:|.|||   .:.|:                .:..||.|  .:|...|:||..|..||.:|
Human   366 DTASLSLTVVQNMEGDK----------------SQQLGRVVVGPYMYTRGRELEHWDEMLSKP 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		Atrophin-1	<299..>500	CDD:460830
		C2A_SLP	3398..3520	CDD:176056	37/123 (30%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	41/184 (22%)
SYT15	XP_016872239.1	C2A_Synaptotagmin-15-17	156..276	CDD:176036	37/124 (30%)
		C2B_Synaptotagmin-15	286..423	CDD:176054	41/188 (22%)