DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btsz and Syt13

DIOPT Version :9

Sequence 1:	NP_001247109.1	Gene:	btsz / 3346167	FlyBaseID:	FBgn0266756	Length:	3734	Species:	Drosophila melanogaster
Sequence 2:	NP_110466.2	Gene:	Syt13 / 80977	RGDID:	621877	Length:	426	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	68/322 - (21%)
Similarity:	124/322 - (38%)	Gaps:	76/322 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  3399 QVEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRS-DPYVKVYLLPDKSKAGKRKTKVKKHTLNP 3462
            ::.|.:.|:.|.:.|.|     ..|.||.:..... |.|::..:.. |:.:.:.:|.:||..|:.
  Rat   161 KLHFRLDYDQKKAELFV-----TSLEAVTSDHEGGCDCYIQGSVAV-KTGSVEAQTALKKRQLHT 219

  Fly  3463 IFDETMRFHTPISSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLFDNPQSQWYLLQERSEPF 3527
            .::|.:........|.:.||.||:...|.|.|:..:||:.:.|.|.......:||..|:..::
  Rat   220 TWEEGLTLPLGEEELPTATLTLTLRTCDRFSRHSVIGELRLGLNGASVPLGTAQWGELKTTAK-- 282

  Fly  3528 DEVATYRGDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIKSVASKSERTSKGGQLHV 3592
             |.:...|::::.:.|:|..|                                        :|.|
  Rat   283 -EPSAGTGEVLLSISYLPAAN----------------------------------------RLLV 306

  Fly  3593 LVKEAKHLSPIKANGTC--DAFCKSYLLPDRTRSSKQKTPVVKRTLHPSWNYTFVYEDVSLEELS 3655
            ::.:||:|...::....  |...|..|.....:..|::|...|..::|.||...::| :..:.|.
  Rat   307 VLIKAKNLHSNQSKELLGKDVSVKVTLKHQAQKLKKKQTKRAKHKINPVWNEMIMFE-LPDDLLQ 370

  Fly  3656 ERALELTVWDHDRLASNEFVGGIRFSLGTGR-----SYGRQVEWMDATGKELSLWQNMLDRP 3712
            ..::||.|                  ||.|.     ..||....:.|:|.|.|.|:.||..|
  Rat   371 ASSVELEV------------------LGQGEEGPSCELGRCSLGLHASGSERSHWEEMLKNP 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		SOBP	<300..476	CDD:291927
		C2A_SLP	3398..3520	CDD:176056	30/121 (25%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	36/186 (19%)
Syt13	NP_110466.2	C2	160..277	CDD:301316	30/121 (25%)
Syt13	NP_110466.2	C2B_Synaptotagmin-13	288..425	CDD:176052	36/186 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010