Protein Alignment btsz and SYT4

DIOPT Version :9

• Sequence 1: NP_001247109.1
• Gene: btsz / 3346167
• FlyBaseID: FBgn0266756
• Length: 3734
• Species: Drosophila melanogaster
• Sequence 2: NP_065834.1
• Gene: SYT4 / 6860
• HGNCID: 11512
• Length: 425
• Species: Homo sapiens
• Alignment Length: 524
• Identity: 121/524 - (23%)
• Similarity: 218/524 - (41%)
• Gaps: 133/524 - (25%)

  Fly  3219 APITSTPKTKSQSALNHTPSNLSTVSATG-------------------SAKSARYRSPGLAARAA 3264
            ||||:     |:...:..|:.:...||.|                   |.|:..|:...:..
Human     2 APITT-----SREEFDEIPTVVGIFSAFGLVFTVSLFAWICCQRKSSKSNKTPPYKFVHVLK--- 58

  Fly  3265 AVSGAGGGSSGGVGVGASSGSTGKKLGAGFQFLYSKRDARKRLNMSAEEAKVAAEELSRSPVIGQ 3329
                       ||.:...:.::.||.||.     .|.:.:.         |.|..:.|....:.:
Human    59 -----------GVDIYPENLNSKKKFGAD-----DKNEVKN---------KPAVPKNSLHLDLEK 98

  Fly  3330 RQADGS--------GSPIQSRASSETWPTQSD-EDIDRLVAMHQNRSSLSSLGVRSESMASVYSG 3385
            |..:|:        |||             || |:....:.:...:.|:|...::|.:  |:.|.
Human    99 RDLNGNFPKTNLKPGSP-------------SDLENATPKLFLEGEKESVSPESLKSST--SLTSE 148

  Fly  3386 AGEGRYGTVVVKGQVEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDKSKAGK 3450
            ..:.:.||:.      |:::||::..|..|::...:.|.|:|.:...||||:|:.:||:|..  |
Human   149 EKQEKLGTLF------FSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKH--K 205

  Fly  3451 RKTKVKKHTLNPIFDETMRFH-TPISSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLFDNPQ 3514
            .||:|.:.||:|.||||..|: .|.:.::...|..|:...|.|.|:|.:|||.:.|.|  .:..:
Human   206 VKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSG--IELSE 268

  Fly  3515 SQWYLLQERSEPFDEVATYRGDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIKSVAS 3579
            .:..:.:|..:.....::.||::::.|.|                  .|::|
Human   269 GKMLMNREIIKRNVRKSSGRGELLISLCY------------------QSTTN------------- 302

  Fly  3580 KSERTSKGGQLHVLVKEAKHLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRTLHPSWNYTF 3644
                     .|.|:|.:|:||.....:|..|.:.|..|...:.|.||:||.|.|.|.:..:|..|
Human   303 ---------TLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELF 358

  Fly  3645 VYEDVSLEELSERALELTVWDHDRLASNEFVGGIRFSL---GTGRSYGRQVEWMDATGKELSLWQ 3706
            |: |:..|.|.:.::|..|.|.:|.:.||.:|.:....   |||..:.:::  .|...::::.|.
Human   359 VF-DIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEI--CDYPRRQIAKWH 420

  Fly  3707 NMLD 3710
            .:.|
Human   421 VLCD 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		SOBP	<300..476	CDD:291927
		C2A_SLP	3398..3520	CDD:176056	40/122 (33%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	43/180 (24%)
SYT4	NP_065834.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..93		6/33 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..147		4/21 (19%)
		C2A_Synaptotagmin-4-11	153..279	CDD:176034	43/135 (32%)
		C2B_Synaptotagmin-4	288..423	CDD:176049	42/177 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920