Protein Alignment btsz and Syt10

DIOPT Version :9

• Sequence 1: NP_001247109.1
• Gene: btsz / 3346167
• FlyBaseID: FBgn0266756
• Length: 3734
• Species: Drosophila melanogaster
• Sequence 2: NP_113854.1
• Gene: Syt10 / 60567
• RGDID: 62041
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 131/602 - (21%)
• Similarity: 228/602 - (37%)
• Gaps: 195/602 - (32%)

  Fly  3140 ESSPAKPWLSSAGSSIGGDSTKDVRRSSVPDAIYETDSSDEAASHQFGGARSTLPRSLNPNQVVA 3204
            :|....|.:|:...||          ||.|..::||:...|...::     ...|:::.|...::
  Rat    85 KSKLVAPNVSTLPQSI----------SSAPTEVFETEEKKEVEENE-----KPAPKAIEPAIKIS 134

  Fly  3205 STNSLPRLPTTGVGAPITSTPKTKSQSALNHTPSNLSTVSATGSAKSARYRSPGLAARAAAVSGA 3269
            .|:  |.:|     |.:.:..|   :..:.|......|...|.|::...:|
  Rat   135 HTS--PDIP-----AEVQTALK---EHLIKHARVQRQTTDPTSSSRHNSFR-------------- 175

  Fly  3270 GGGSSGGVGVGASSGSTGKKLGAGFQFLYSKRDARKRLNMSAEEAKVAAEELSRSPVIGQRQADG 3334
                                           |...:::|:|:.:..:..|
  Rat   176 -------------------------------RHLPRQMNVSSVDFSMGTE--------------- 194

  Fly  3335 SGSPIQSRASSETWPTQSDEDIDRLVAMHQNRSSLSSLGVRSESMASVYSGAGEGRYGTVVVKGQ 3399
               |:..|..:.|       .|.|:......:.|:.|.|.|.:.:.:.               |:
  Rat   195 ---PVLQRGETRT-------SIGRIKPELYKQKSVDSEGNRKDDVKTC---------------GK 234

  Fly  3400 VEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDKSKAGKRKTKVKKHTLNPIF 3464
            :.||:||:|:...|.|.:::..||.|.|. ...||||||:|||||:.|  |.:|:|.:.||||:|
  Rat   235 LNFALQYDYENELLVVKIIKALDLPAKDF-TGTSDPYVKIYLLPDRKK--KFQTRVHRKTLNPLF 296

  Fly  3465 DETMRFHTPISSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLFDNPQSQWYLLQERSEPFDE 3529
            ||..:|......|.:|.|..:::..|.|.|:|.:|||       :.||       |.|.|:...|
  Rat   297 DELFQFPVVYDQLSNRKLHFSIYDFDRFSRHDMIGEV-------ILDN-------LFEVSDLSRE 347

  Fly  3530 VATYR------------GDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIKSVASKSE 3582
            ...::            |:|:..|.|:|
  Rat   348 ATVWKDIHCATTESIDLGEIMFSLCYLP------------------------------------- 375

  Fly  3583 RTSKGGQLHVLVKEAKHLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRTLHPSWNYTFVYE 3647
               ..|::.:.|.:.::|..:...|:.|.:.|..|:.:..|..|:||...|.||:|.:|...::
  Rat   376 ---TAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIF- 436

  Fly  3648 DVSLEELSERALELTVWDHDRLASNEFVGGIRFSL---GTGRSYGRQVEWMDATG---KELSLWQ 3706
            |:..|.:.:.:|.:.|.|:||:..||.:|..|..|   |.||.:     |.:...   |.::.|.
  Rat   437 DIPPENVDQVSLCIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDH-----WNEMLAYHRKPITHWH 496

  Fly  3707 NMLDRP----NFWVEGS 3719
            .:|:.|    :|..:||
  Rat   497 PLLELPGRATSFDSQGS 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		SOBP	<300..476	CDD:291927
		C2A_SLP	3398..3520	CDD:176056	47/121 (39%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	44/208 (21%)
Syt10	NP_113854.1	Cysteine motif. /evidence=ECO:0000250|UniProtKB:O35681	13..35
		C2A_Synaptotagmin-1-5-6-9-10	231..356	CDD:176031	51/156 (33%)
		C2B_Synaptotagmin-3-5-6-9-10	365..498	CDD:176048	39/178 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920