Protein Alignment btsz and Syt10

DIOPT Version :9

• Sequence 1: NP_001247109.1
• Gene: btsz / 3346167
• FlyBaseID: FBgn0266756
• Length: 3734
• Species: Drosophila melanogaster
• Sequence 2: NP_061273.1
• Gene: Syt10 / 54526
• MGIID: 1859546
• Length: 523
• Species: Mus musculus
• Alignment Length: 602
• Identity: 134/602 - (22%)
• Similarity: 227/602 - (37%)
• Gaps: 195/602 - (32%)

  Fly  3140 ESSPAKPWLSSAGSSIGGDSTKDVRRSSVPDAIYETDSSDEAASHQFGGARSTLPRSLNPNQVVA 3204
            :|....|.||....||          ||.|..::||:...|...::     ...|:::.|...::
Mouse    85 KSKLVAPNLSVLPQSI----------SSAPTEVFETEEKKEVEENE-----KPAPKAIEPAIKIS 134

  Fly  3205 STNSLPRLPTTGVGAPITSTPKTKSQSALNHTPSNLSTVSATGSAKSARYRSPGLAARAAAVSGA 3269
            .|:  |.:|     |.:.:..|   :..:.|......|...|.|::...:|
Mouse   135 HTS--PDIP-----AEVQTALK---EHLIKHARVQRQTTEPTSSSRHNSFR-------------- 175

  Fly  3270 GGGSSGGVGVGASSGSTGKKLGAGFQFLYSKRDARKRLNMSAEEAKVAAEELSRSPVIGQRQADG 3334
                                           |...:::|:|:.:..|..|
Mouse   176 -------------------------------RHLPRQMNVSSVDFSVGTE--------------- 194

  Fly  3335 SGSPIQSRASSETWPTQSDEDIDRLVAMHQNRSSLSSLGVRSESMASVYSGAGEGRYGTVVVKGQ 3399
               ||..|..:.|       .|.|:......:.|:.|.|.|.:.:.:.               |:
Mouse   195 ---PILQRGETRT-------SIGRIKPELYKQKSVDSEGNRKDDVKTC---------------GK 234

  Fly  3400 VEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDKSKAGKRKTKVKKHTLNPIF 3464
            :.||:||:|:...|.|.:::..||.|.|. ...||||||:|||||:.|  |.:|:|.:.||||:|
Mouse   235 LNFALQYDYENELLVVKIIKALDLPAKDF-TGTSDPYVKIYLLPDRKK--KFQTRVHRKTLNPLF 296

  Fly  3465 DETMRFHTPISSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLFDNPQSQWYLLQERSEPFDE 3529
            ||..:|......|.:|.|..:::..|.|.|:|.:|||       :.||       |.|.|:...|
Mouse   297 DELFQFPVVYDQLSNRKLHFSIYDFDRFSRHDMIGEV-------ILDN-------LFEVSDLSRE 347

  Fly  3530 VATYR------------GDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIKSVASKSE 3582
            ...::            |:|:..|.|:|
Mouse   348 ATVWKDIHCATTESIDLGEIMFSLCYLP------------------------------------- 375

  Fly  3583 RTSKGGQLHVLVKEAKHLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRTLHPSWNYTFVYE 3647
               ..|::.:.|.:.::|..:...|:.|.:.|..|:.:..|..|:||...|.||:|.:|...::
Mouse   376 ---TAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIF- 436

  Fly  3648 DVSLEELSERALELTVWDHDRLASNEFVGGIRFSL---GTGRSYGRQVEWMDATG---KELSLWQ 3706
            |:..|.:.:.:|.:.|.|:||:..||.:|..|..|   |.||.:     |.:...   |.::.|.
Mouse   437 DIPPENVDQVSLCIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDH-----WNEMLAYHRKPITHWH 496

  Fly  3707 NMLDRP----NFWVEGS 3719
            .:|:.|    :|..:||
Mouse   497 PLLELPGRATSFDSQGS 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		SOBP	<300..476	CDD:291927
		C2A_SLP	3398..3520	CDD:176056	47/121 (39%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	44/208 (21%)
Syt10	NP_061273.1	Cysteine motif. /evidence=ECO:0000250|UniProtKB:O35681	13..35
		C2A_Synaptotagmin-1-5-6-9-10	231..356	CDD:176031	51/156 (33%)
		C2B_Synaptotagmin-3-5-6-9-10	365..498	CDD:176048	39/178 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920