DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btsz and syt5a

DIOPT Version :9

Sequence 1:	NP_001247109.1	Gene:	btsz / 3346167	FlyBaseID:	FBgn0266756	Length:	3734	Species:	Drosophila melanogaster
Sequence 2:	NP_001096607.1	Gene:	syt5a / 436686	ZFINID:	ZDB-GENE-040718-110	Length:	405	Species:	Danio rerio

Alignment Length:	332	Identity:	100/332 - (30%)
Similarity:	156/332 - (46%)	Gaps:	73/332 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  3385 GAGEGRYGTVVVKGQVEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDKSKAG 3449
            |.||..|     .|::|:.:.||:..:.|.|.:::.:||.|:|. ...||||||||:||||.|
Zfish   118 GEGEKEY-----YGKLEYTLDYNFTENQLIVGILQAQDLPAMDI-GGTSDPYVKVYMLPDKKK-- 174

  Fly  3450 KRKTKVKKHTLNPIFDETMRFHTPISSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLFDNPQ 3514
            |.:|||::..|.|:|:||..|..|.:.|..:||.|.|:..|.||::|.:||:.:.:.......|.
Zfish   175 KFETKVQRKNLCPVFNETFIFKIPFNDLAGQTLVLQVFDFDRFGKHDVIGEIKIPMNSIDLGQPI 239

  Fly  3515 SQWYLL----QERSEPFDEVATYRGDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIK 3575
            .::..|    :|..|..       |||.:.|:|:|
Zfish   240 HEYKDLVGGEKEEQEKL-------GDICISLRYVP------------------------------ 267

  Fly  3576 SVASKSERTSKGGQLHVLVKEAKHLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRTLHPSW 3640
                    ||  |:|.|.:.|||:|..:...|..|.|.|..|..:..|..|:||.|.:.||:|.:
Zfish   268 --------TS--GKLTVCIMEAKNLKKMDVGGLSDPFVKIVLQHNGKRIKKKKTTVKQNTLNPYF 322

  Fly  3641 NYTFVYEDVSLEELSERALELTVWDHDRLASNEFVGGIRFSLGTGRSYGRQVEWMDATGKELSLW 3705
            |.:|.:| :...::.:..:.:||:|:|:|.||:.:|......|             |:|..|..|
Zfish   323 NESFSFE-IPFAQIQKVQVLITVYDYDKLGSNDPIGKCWIGFG-------------ASGVGLRHW 373

  Fly  3706 QNMLDRP 3712
            .:||..|
Zfish   374 SDMLANP 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		SOBP	<300..476	CDD:291927
		C2A_SLP	3398..3520	CDD:176056	46/121 (38%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	47/179 (26%)
syt5a	NP_001096607.1	C2A_Synaptotagmin-1-5-6-9-10	128..246	CDD:176031	45/120 (38%)
syt5a	NP_001096607.1	C2B_Synaptotagmin-1	256..391	CDD:176047	47/186 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920