Protein Alignment btsz and Syt12

DIOPT Version :10

• Sequence 1: NP_001247109.1
• Gene: btsz / 3346167
• FlyBaseID: FBgn0266756
• Length: 3734
• Species: Drosophila melanogaster
• Sequence 2: NP_620190.1
• Gene: Syt12 / 191595
• RGDID: 621876
• Length: 421
• Species: Rattus norvegicus
• Alignment Length: 513
• Identity: 124/513 - (24%)
• Similarity: 202/513 - (39%)
• Gaps: 128/513 - (24%)

  Fly  3232 ALNHTPSNLSTVSATGSAKSARYRSPGLAARAAAVSGAGGGSSGGVGVGASSGSTGKKLGAGFQF 3296
            |::.|..:||.:.:....:...|     ||.|.|:.|....|...:....|..|........:::
  Rat     2 AVDVTEYHLSVIKSPPGWEVGVY-----AAGALALLGIAAVSLWKLWTSGSFPSPSPFPNYDYRY 61

  Fly  3297 LYSKRDARKRLNMSAEEAKVAAEELSRSPVIGQRQADGSGSPIQSRASSETWPTQSDEDIDRLVA 3361
            |..|..          ||.|.| :|.|.|....::....|.|  ||..|              ::
  Rat    62 LQQKYG----------EAYVEA-KLKRVPPWNAQRTTTRGPP--SRKGS--------------LS 99

  Fly  3362 MHQNRSSLSSLGV-----------------RSESMASVYS-GAGEGRYGTVVVKGQVEFAMQYNY 3408
            :.....|:|.||.                 :|:|..|:.| .:....:|.....||||.:|.|:.
  Rat   100 IEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMDYDG 164

  Fly  3409 KLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDKSKAGKRKTKVKKHTLNPIFDETMRFHTP 3473
            ....|.|.|::.|||...:.....| .:::|.||||:...|  .::::::..:..|||  :|..|
  Rat   165 ASHTLHVAVLQGKDLLEREEATFES-CFMRVSLLPDEQIVG--ISRIQRNAYSIFFDE--KFSVP 224

  Fly  3474 I--SSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLFD---NPQSQWYLLQERSEPFDEVATY 3533
            :  ::||.::|..:|:..|...||...|.|.:.|.  :.|   .|.|.|..||::::..|.|
  Rat   225 LDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLS--VLDLPLQPFSGWLYLQDQNKAADAV--- 284

  Fly  3534 RGDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIKSVASKSERTSKGGQLHVLVKEAK 3598
             |:|::.|.|:|                                  .:||      |.|:|.:||
  Rat   285 -GEILLSLSYLP----------------------------------TAER------LTVVVVKAK 308

  Fly  3599 HLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRTLHPSWNYTFVYE--DVSLEELSERALEL 3661
            :|.......|.|.|.|.|||.|..:.||:||.|.:...:|.:|...::.  .:.|::||   |.:
  Rat   309 NLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLS---LRV 370

  Fly  3662 TVWDHDRLASNEFVGGIRFSLGTGRSYGRQVEWMDATGKELSLWQNM---LDRP-NFW 3715
            ||.:..             |.|.|.:.|..:....|:|...:.|..|   |.|| :.|
  Rat   371 TVAESS-------------SDGRGDNVGHVIIGPGASGMGTTHWNQMLATLRRPVSMW 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		Atrophin-1	<299..>500	CDD:460830
		C2A_SLP	3398..3520	CDD:176056	38/126 (30%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	46/188 (24%)
Syt12	NP_620190.1	C2	152..263	CDD:472691	34/117 (29%)
		C2B_Synaptotagmin-12	284..419	CDD:176051	47/192 (24%)