DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btsz and snt-3

DIOPT Version :9

Sequence 1:	NP_001247109.1	Gene:	btsz / 3346167	FlyBaseID:	FBgn0266756	Length:	3734	Species:	Drosophila melanogaster
Sequence 2:	NP_001379881.1	Gene:	snt-3 / 190698	WormBaseID:	WBGene00004923	Length:	284	Species:	Caenorhabditis elegans

Alignment Length:	316	Identity:	93/316 - (29%)
Similarity:	161/316 - (50%)	Gaps:	65/316 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  3398 GQVEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDKSKAGKRKTKVKKHTLNP 3462
            |::::.:.|::..::|.|.:::.::|.|:|. ...||||||::|||||.|  |.:|||::.:|||
Worm    17 GRLQYKLDYDFDKNSLTVVIIQAEELPAMDL-GGTSDPYVKLFLLPDKKK--KLQTKVQRKSLNP 78

  Fly  3463 IFDETMRFHTPISSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLFDNPQSQWYLLQERSEPF 3527
            :|:|:..|..|.:.:..:||.|.|:..|.||::|.:|::|:.| |::      ......||::..
Worm    79 VFNESFTFKIPFNEIGGQTLVLNVFDFDRFGKHDQIGQISIPL-GKV------DLAATLERTDLI 136

  Fly  3528 DEVATYR-GDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIKSVASKSERTSKGGQLH 3591
            :.....| |::.:.|:|:|.:|                                        :|.
Worm   137 ESPPENRLGEVCLALRYVPNKN----------------------------------------KLS 161

  Fly  3592 VLVKEAKHLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRTLHPSWNYTFVYEDVSLEELSE 3656
            |:|.|.|:|..:...|..|.:.|.||:....|..|:||.:..:||:|.:|.:|.: ||:.|::..
Worm   162 VVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTLNPYYNESFSF-DVTSEKMQR 225

  Fly  3657 RALELTVWDHDRLASNEFVGGIRFSLGTGRSYGRQVEWMDATGKELSLWQNMLDRP 3712
            ..|.:||.|:||:.|||.:|.:  .:||           .|||..|..|.:||..|
Worm   226 VHLHVTVSDYDRVGSNERIGQV--IIGT-----------CATGVALKQWNDMLATP 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		SOBP	<300..476	CDD:291927
		C2A_SLP	3398..3520	CDD:176056	42/121 (35%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	49/180 (27%)
snt-3	NP_001379881.1	C2	16..131	CDD:417471	42/123 (34%)
snt-3	NP_001379881.1	C2B_Synaptotagmin-1	144..278	CDD:176047	48/179 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920