DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment btsz and snt-6

DIOPT Version :9

Sequence 1:NP_001247109.1 Gene:btsz / 3346167 FlyBaseID:FBgn0266756 Length:3734 Species:Drosophila melanogaster
Sequence 2:NP_001254022.1 Gene:snt-6 / 182427 WormBaseID:WBGene00004926 Length:373 Species:Caenorhabditis elegans


Alignment Length:318 Identity:81/318 - (25%)
Similarity:140/318 - (44%) Gaps:56/318 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly  3397 KGQVEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDKSKAGKRKTKVKKHTLN 3461
            :|::.|::.:..:.|.|.||::...||...|. ...|||||:.:||.|..::  .::||.:..||
 Worm   102 RGRINFSVAFEKECSTLHVHLMEAVDLPVKDF-TGSSDPYVRAFLLQDPGQS--ERSKVHRRNLN 163

  Fly  3462 PIFDETMRF--HTPISSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLFDNPQSQWYLLQERS 3524
            |.|:||:.|  |: :..|...||.|.|...|.|..:|.:||:.:.|:...|::....|..||..:
 Worm   164 PTFNETLSFRGHS-MKKLHDMTLVLQVMDYDRFSSDDPIGEILLPLKHVKFESSPVYWKHLQRPT 227

  Fly  3525 EPFDEVATYRGDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIKSVASKSERTSKGGQ 3589
            ...|..    |:|::.|.|:|                                      ||  |:
 Worm   228 VSKDAC----GEIMISLCYLP--------------------------------------TS--GK 248

  Fly  3590 LHVLVKEAKHLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRTLHPSWNYTFVYE-DVSLEE 3653
            :.|.:.:|:.|.........|.:.|.:::....:..|:||.|...|..|.:|.:|.:. .|....
 Worm   249 ITVSIIKARDLHAKDRTRHYDTYVKMWMVQQGNKLEKRKTSVKPHTPSPIFNESFAFSIPVKQVL 313

  Fly  3654 LSERALELTVWDHDRLASNEFVGGIRFSLGTGRSYGRQVEWMDATG---KELSLWQNM 3708
            |:|..|.||..::|.:.|||.:|.:... |.|..:| |..|.:...   :.:::|..:
 Worm   314 LAEVNLVLTAMEYDVIGSNEEIGHVIVG-GLGSEHG-QRHWSECVNHPEQPVAMWHKL 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
btszNP_001247109.1 FYVE_Slp3_4_5 26..73 CDD:277286
SOBP <300..476 CDD:291927
C2A_SLP 3398..3520 CDD:176056 40/123 (33%)
C2B_SLP_1-2-3-4 3534..3723 CDD:175987 38/179 (21%)
snt-6NP_001254022.1 C2 101..225 CDD:387358 41/126 (33%)
C2B_Synaptotagmin 234..369 CDD:175975 38/176 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D925064at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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