DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btsz and snt-5

DIOPT Version :9

Sequence 1:	NP_001247109.1	Gene:	btsz / 3346167	FlyBaseID:	FBgn0266756	Length:	3734	Species:	Drosophila melanogaster
Sequence 2:	NP_503409.1	Gene:	snt-5 / 178631	WormBaseID:	WBGene00004925	Length:	458	Species:	Caenorhabditis elegans

Alignment Length:	366	Identity:	87/366 - (23%)
Similarity:	155/366 - (42%)	Gaps:	77/366 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  3354 EDIDRLVAMHQNRSSLSSLGVRSESMASVYSGAGEGRYGTVVVKGQVEFAMQYNYKLSALEVHVV 3418
            ||||....||.      .||        .|.....|     .::|.:.||::|::....|.:||:
Worm   145 EDIDERSVMHY------ELG--------FYDKTDGG-----CIRGTLTFALRYDFIHRVLMLHVI 190

  Fly  3419 RCKDLAAVDAKRNRSDPYVKVYLLPDKSKAGKRKTKVKKHTLNPIFDETMRFHTPISSLESRTLW 3483
            |..:| .|:.|....|||||:||||:  :.|..||::.|.|.:|.|:|...|....::|.:|.|.
Worm   191 RANNL-PVEDKGVTVDPYVKMYLLPE--RRGHCKTRICKKTNDPEFNEMFSFDVSFNNLANRMLQ 252

  Fly  3484 LTVWHSDMFGRNDFLGEVSVNLQGRLFDNPQSQWYLLQERSEPFDEVATYRGDIVVGLKYIPPEN 3548
            .||:..|.|.|:..:|.:   :...||:  :|..|...|          |...||
Worm   253 FTVYDFDRFTRHGLIGNI---IMRDLFE--KSDLYTWTE----------YTMHIV---------- 292

  Fly  3549 IKSSFFSRGSSITGSSSNLRKFGGSIKSVASKSERTSKGGQLHVLVKEAKHLSPIKANGTCDAFC 3613
                          :|.|...:|..:..:...::..    :|::.|.:|.:|.|:...|..|.:.
Worm   293 --------------ASQNKNDYGDLLLFLTYSNQEE----KLYINVSKAYNLRPMDITGASDPYV 339

  Fly  3614 KSYLLPDRTRSSKQKTPVVKRTLHPSWNYTFVYEDVSLEELSERALELTVWDHDRLASNEFVGGI 3678
            |.....:..|...:|:...:..|:|.::.|.|: |:...:::|..:.:.|.|.||:..::.:|..
Worm   340 KIEQTFNGKRFKSKKSSTKRANLNPVFHETLVF-DIPSSQIAETNILIQVMDWDRIGKDDLLGCC 403

  Fly  3679 RFSLGTGRSYGRQVEW---MDATGKELSL-------WQNML 3709
            .....:..:.|: .:|   ::|..:|..|       |.::|
Worm   404 ILGKDSPTADGK-TQWDNCLNAVPEEGQLKNKPVGQWHSLL 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		SOBP	<300..476	CDD:291927
		C2A_SLP	3398..3520	CDD:176056	42/121 (35%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	33/186 (18%)
snt-5	NP_503409.1	C2	169..277	CDD:301316	39/113 (35%)
snt-5	NP_503409.1	C2B_Synaptotagmin	301..442	CDD:175975	28/146 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920