DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btsz and LOC100493529

DIOPT Version :9

Sequence 1:	NP_001247109.1	Gene:	btsz / 3346167	FlyBaseID:	FBgn0266756	Length:	3734	Species:	Drosophila melanogaster
Sequence 2:	XP_002932169.1	Gene:	LOC100493529 / 100493529	-ID:	-	Length:	428	Species:	Xenopus tropicalis

Alignment Length:	317	Identity:	97/317 - (30%)
Similarity:	157/317 - (49%)	Gaps:	64/317 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  3398 GQVEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDKSKAGKRKTKVKKHTLNP 3462
            |:::|::.|:::.:.::|.:::..:|.|:| ....|||||||:.||||.|  |.:|||.:.||||
Frog   150 GKLQFSLDYDFQNNQMQVGIIQATELPALD-MGGTSDPYVKVFFLPDKKK--KHETKVHRKTLNP 211

  Fly  3463 IFDETMRFHTPISSLESRTLWLTVWHSDMFGRNDFLGEVSVNLQGRLFDNPQSQWYLLQ--ERSE 3525
            ||:||..|..|...|..:||.::::..|.|.::|.:|||.|.:.......|..:|..||  |:.|
Frog   212 IFNETFTFKIPYQELGGKTLCMSIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQSAEKEE 276

  Fly  3526 PFDEVATYRGDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKFGGSIKSVASKSERTSKGGQL 3590
            |     ...|||.:.|:|:|                                        ..|:|
Frog   277 P-----EKLGDICISLRYVP----------------------------------------TAGKL 296

  Fly  3591 HVLVKEAKHLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRTLHPSWNYTFVYEDVSLEELS 3655
            .|.:.|||:|..:...|..|.:.|.:|:.:..|..|:||.|.|:||:|.:|.:|.:| :..|::.
Frog   297 TVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQ 360

  Fly  3656 ERALELTVWDHDRLASNEFVGGIRFSLGTGRSYGRQVEWMDATGKELSLWQNMLDRP 3712
            :..:.:||.|:|:|..||.:|.|...             .:|:|.||..|.:||..|
Frog   361 KVQVVITVLDYDKLGKNEAIGKIFVG-------------CNASGTELRHWSDMLANP 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		SOBP	<300..476	CDD:291927
		C2A_SLP	3398..3520	CDD:176056	45/121 (37%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	47/179 (26%)
LOC100493529	XP_002932169.1	C2A_Synaptotagmin-1-5-6-9-10	153..271	CDD:176031	45/120 (38%)
LOC100493529	XP_002932169.1	C2B_Synaptotagmin-1	280..415	CDD:176047	47/179 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920