DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btsz and syt8

DIOPT Version :9

Sequence 1:	NP_001247109.1	Gene:	btsz / 3346167	FlyBaseID:	FBgn0266756	Length:	3734	Species:	Drosophila melanogaster
Sequence 2:	XP_012815834.1	Gene:	syt8 / 100037878	XenbaseID:	XB-GENE-978920	Length:	396	Species:	Xenopus tropicalis

Alignment Length:	337	Identity:	97/337 - (28%)
Similarity:	156/337 - (46%)	Gaps:	71/337 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  3382 VYSGAGEGRYG-TVVVKGQVEFAMQYNYKLSALEVHVVRCKDLAAVDAKRNRSDPYVKVYLLPDK 3445
            |..|||..:.| .|..:|:|:::::||::...|.|.|.:...|.|:|. ...||||..||:..|.
Frog    90 VQPGAGNLQKGEKVEYRGRVQYSLEYNFQTEELTVGVKQAAALKAMDL-GGTSDPYAIVYVTNDT 153

  Fly  3446 SKAGKRKTKVKKHTLNPIFDETMRFHTPISSLESRTLWLTVWHSDMFGRNDFLGEV-----SVNL 3505
            .|  |.:|||.:.||||:|:|:..|......:...|..:.::..:.|.::|.:||:     .|||
Frog   154 RK--KFETKVNRKTLNPVFNESFVFKVTQEEVPRTTAVVQIFDFNRFLKHDVIGEMVIPLGEVNL 216

  Fly  3506 QGRLFDNPQSQWYLLQERSEPFDEVATYRGDIVVGLKYIPPENIKSSFFSRGSSITGSSSNLRKF 3570
            |..:.|     |..|....:...|   :.|||...|:|:|
Frog   217 QHVIED-----WKDLGPAGKTEHE---HLGDICFSLRYVP------------------------- 248

  Fly  3571 GGSIKSVASKSERTSKGGQLHVLVKEAKHLSPIKANGTCDAFCKSYLLPDRTRSSKQKTPVVKRT 3635
                           ..|:|.:::.|||:|..:.::|..|.:.|.:|..:|.:..::||.|.|.|
Frog   249 ---------------SSGKLTIIILEAKNLKRMDSDGFSDPYVKVHLALNRKKWKRKKTAVKKST 298

  Fly  3636 LHPSWNYTFVYEDVSLEELSERALELTVWDHDRLASNEFVGGIRFSLGTGRSYGRQVEWMDATGK 3700
            |.|.:|.:|.: |||||::....|.::|||||::..||.:|  :..||           ..|:|.
Frog   299 LKPYFNESFTF-DVSLEQMKNLDLIISVWDHDKVGKNEQIG--KLFLG-----------CRASGN 349

  Fly  3701 ELSLWQNMLDRP 3712
            .|..|.:||..|
Frog   350 ALRHWSDMLAHP 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btsz	NP_001247109.1	FYVE_Slp3_4_5	26..73	CDD:277286
		SOBP	<300..476	CDD:291927
		C2A_SLP	3398..3520	CDD:176056	40/126 (32%)
		C2B_SLP_1-2-3-4	3534..3723	CDD:175987	49/179 (27%)
syt8	XP_012815834.1	C2A_Synaptotagmin-1-5-6-9-10	105..228	CDD:176031	41/130 (32%)
syt8	XP_012815834.1	C2B_Synaptotagmin-1	237..372	CDD:176047	49/179 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920