DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr4 and Igsf9

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	258	Identity:	59/258 - (22%)
Similarity:	96/258 - (37%)	Gaps:	51/258 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PPHYWETPYSQPYFDNSSRREVTATVGQAALLHCRVRNLGDRAVSW-IRKRDLHILTVGILTYTN 97
            ||.:.|||   |........|       |..|.|..|......|:| .|.:||
Mouse   135 PPQFQETP---PLVLEVKELE-------AVTLRCVARGSPQPYVTWKFRGQDL------------ 177

  Fly    98 DQRFQSLHSEGSDE-----WTLRISSPQPRDSGTYECQV-STEPKISQGFRLNVVVSRAKILGNA 156
                    .:|..:     .||.|...:...:|.|.||. |:|..|:...:|.|:.....::..:
Mouse   178 --------GKGQGQVQVQNGTLWIRRVERGSAGDYTCQASSSEGSITHATQLLVLGPPVIVVPPS 234

  Fly   157 ELFIKSGSDINLTCLAMQSPVPPSFIYWYKGKRVMNYSQ-RGGINVITERSTRTSKLLIAKATPA 220
            ...:.|..|::|.|.|...|...::.::..|..|.:.|: :..:.::.:.|     |.:....|.
Mouse   235 NSTVNSSQDVSLACRAEAYPANLTYSWFQDGVNVFHISRLQSRVRILVDGS-----LWLQATQPD 294

  Fly   221 DSGNYTCSPSSS----DSASVVVHVINGEHPAAMQHGNSSATCLRPLSSTSV----PFVLATW 275
            |:|:|||.||:.    .|||..:.|:.......|.......|.:|.:....|    |.:..||
Mouse   295 DAGHYTCVPSNGFLHPPSASAYLTVLYPAQVTVMPPETPLPTGMRGVIRCPVRANPPLLFVTW 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	22/99 (22%)
		IG_like	53..145	CDD:214653	22/98 (22%)
		ig	153..227	CDD:278476	15/74 (20%)
		IG_like	161..>227	CDD:214653	15/66 (23%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653
		Ig	136..223	CDD:386229	27/116 (23%)
		Ig_3	227..305	CDD:372822	18/82 (22%)
		Ig	341..404	CDD:386229	4/17 (24%)
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900