DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr4 and CG34353

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster

Alignment Length:	253	Identity:	66/253 - (26%)
Similarity:	105/253 - (41%)	Gaps:	40/253 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SQPYFDNSSRREVTATV-GQAALLHCRVRNLGDRAVSWIRKRDLHILTVGILTYTNDQRFQSLHS 106
            ::|.|  .||.|....: |:..:|.|.|.|.....|:|  ||.:.|||.|.:..|.|.|.:.::.
  Fly    84 NEPMF--ISRSETFKFITGETIVLPCEVANTDTYVVAW--KRGIAILTAGSVKVTPDPRVRLVNG 144

  Fly   107 EGSDEWTLRISSPQPRDSGTYECQVST-EPK-ISQGFRLNVVVSRAKILGNAELFIKSGSDINLT 169
                 :.|:|....|.|:|.|.||::| :|: |:....:.|......|.....|.:|.||.:.:.
  Fly   145 -----FNLQIRDALPTDAGDYICQIATMDPREITHTVEILVPPRIHHISTGGHLQVKKGSSVRIE 204

  Fly   170 CLAMQSPVPPSFIYWYKGKRVMNYSQRGGINVITERSTRTSKLLIAKATPADSGNYTCS------ 228
            |.|..:|:|.           :.:|::..|....|....:..|.|........|.|.|:
  Fly   205 CSATGNPMPN-----------VTWSRKNNILPNGEEKLHSHVLSIENVDRHKGGVYICTANNRVG 258

  Fly   229 -PSSSDSASVVVHV-----INGEHPAAMQHGNSSATCLRPLSSTSVPFVLATWMSMTV 280
             |:||   .||:||     |:.|.|.........||.:..:...:.|.|:  |...|:
  Fly   259 QPASS---QVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGETQPEVI--WFKDTM 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	28/95 (29%)
		IG_like	53..145	CDD:214653	28/94 (30%)
		ig	153..227	CDD:278476	15/73 (21%)
		IG_like	161..>227	CDD:214653	14/65 (22%)
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	27/86 (31%)
		Ig	103..177	CDD:143165	26/80 (33%)
		IG_like	191..269	CDD:214653	21/91 (23%)
		IGc2	198..258	CDD:197706	14/70 (20%)
		I-set	273..360	CDD:254352	9/41 (22%)
		Ig	290..359	CDD:143165	6/24 (25%)
		FN3	<466..524	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810