DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr4 and igsf9b

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	XP_686205.6	Gene:	igsf9b / 553348	ZFINID:	ZDB-GENE-060810-28	Length:	2021	Species:	Danio rerio

Alignment Length:	279	Identity:	61/279 - (21%)
Similarity:	108/279 - (38%)	Gaps:	55/279 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PPHYWETPYSQPYFDNSSRREVTATVGQAALLHCRVRNLGDRAVSWIRKRDLHILTVGILTYTND 98
            ||.:.:||  .|:.:        ..:|::..|||.........:.| ||.        :......
Zfish   140 PPVFIKTP--PPFLE--------VLLGESLTLHCDAHGNPKPTIIW-RKY--------LSAAEKQ 185

  Fly    99 QRFQSLHSEGSDEWTLRISSPQPRDSGTYECQVS-TEPKISQGFRLNVVVSRAKILGNAELFIKS 162
            :..|.|:.      ||.:|......:|.|:|.|| :|..::...:|.|......|:...:..:..
Zfish   186 EEIQVLNE------TLSLSKVTRETAGIYKCHVSNSEGNLTHSTQLQVKGPPIIIIAPEDTTMNM 244

  Fly   163 GSDINLTCLAMQSPVPPSFIYWYKGKRVMNYS-QRGGINVITERSTRTSKLLIAKATPADSGNYT 226
            ..|..|.|.|...|...::.:|.:|:.|.:.. .:..:.::.:     ..|||:...|.||||||
Zfish   245 SQDAVLQCQAEAYPSNLTYEWWKQGQNVYHIEILKSRVKILVD-----GTLLISALIPDDSGNYT 304

  Fly   227 CSPSSS----DSASVVVHVINGEHPAAMQHGNSSATCLRPLSSTSVPFVLATWMSMTVAS----- 282
            |.|::.    .:||..:.|   :|||.:         :|....|.:|..:...:...|.:
Zfish   305 CRPTNGLMTPPAASAYLTV---KHPARV---------VRMPRETYLPMGMGGKIPCPVQAEPPML 357

  Fly   283 -VAWNSN-LNINWNWSPDW 299
             |.|..: .::|....|.|
Zfish   358 YVNWTKDGASLNLEQYPGW 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	19/93 (20%)
		IG_like	53..145	CDD:214653	19/92 (21%)
		ig	153..227	CDD:278476	17/74 (23%)
		IG_like	161..>227	CDD:214653	17/66 (26%)
igsf9b	XP_686205.6	Ig	27..132	CDD:299845
		IG_like	148..227	CDD:214653	20/101 (20%)
		IGc2	156..217	CDD:197706	17/75 (23%)
		Ig	237..323	CDD:299845	22/90 (24%)
		IG_like	237..323	CDD:214653	22/90 (24%)
		Ig	345..411	CDD:143165	6/32 (19%)
		IG_like	435..507	CDD:214653
		IGc2	437..496	CDD:197706
		FN3	512..603	CDD:238020
		FN3	621..709	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910