DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr4 and Gm1123

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001074245.1	Gene:	Gm1123 / 382097	MGIID:	2685969	Length:	390	Species:	Mus musculus

Alignment Length:	221	Identity:	46/221 - (20%)
Similarity:	84/221 - (38%)	Gaps:	55/221 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 GQAALLHCRV----RNLGDRAVSWIR-------KRDLHILTVGILTYTNDQRFQSLHSE------ 107
            |:...|.|..    ::.|...:.|:|       ..| |:    ::.|:.|:....::.:
Mouse   159 GETVHLPCMFTFISKDQGPLNIEWLRLSGPNNEAMD-HV----VILYSADKIHDDVYPDLKGRVY 218

  Fly   108 ------GSDEWTLRISSPQPRDSGTYECQVSTEP-KISQGFRLNVV--VSRAKILGNAELFIKS- 162
                  .|.:.::.|::.|..|:|||:|:|.|.| .:::..:|.|.  :....|....:...|:
Mouse   219 FTSNDIKSGDASINITNVQLSDAGTYQCKVKTYPGTVNRNLQLAVTDHIGSVSITTPEQTIQKAR 283

  Fly   163 GSDINLTCLAMQSPVP--PSFIYW-----------------YKGKRVMN--YSQRGGINVITERS 206
            |..::|.|....||..  |.||.|                 |...::.:  |....|....|...
Mouse   284 GETVHLPCTFTLSPEDHGPLFIDWMQLTGPQNEVVNRMFIVYLADKIYDNFYQDMKGRVQFTSND 348

  Fly   207 TRT--SKLLIAKATPADSGNYTCSPS 230
            .|:  :.:.|..|..:|:|.|.|..|
Mouse   349 IRSGEASINITDARLSDAGTYQCGVS 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	22/109 (20%)
		IG_like	53..145	CDD:214653	22/108 (20%)
		ig	153..227	CDD:278476	20/97 (21%)
		IG_like	161..>227	CDD:214653	20/89 (22%)
Gm1123	NP_001074245.1	V-set	24..139	CDD:284989
		IG_like	25..138	CDD:214653
		V-set	149..264	CDD:284989	22/109 (20%)
		IG_like	152..263	CDD:214653	22/108 (20%)
		V-set	274..389	CDD:284989	22/101 (22%)
		IG_like	277..388	CDD:214653	22/98 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105520
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810