DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr4 and DIP-iota

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	239	Identity:	69/239 - (28%)
Similarity:	101/239 - (42%)	Gaps:	25/239 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LVPLWLLLFLD-CGMVGGEVPPHYWETPYSQPYFD---NSSRREVTATVGQAALLHCRVRNLGDR 75
            |...||||... |.....     :.|...|.|.|.   |:|    |..||:.|||.|.|.:|...
  Fly     5 LPSFWLLLLQSVCFSQAS-----FSELNNSDPKFSGPINNS----TVPVGRDALLTCVVHDLVSF 60

  Fly    76 AVSWIRKRDLHILTVGILTYTNDQRFQSLHSEGSDEWTLRISSPQPRDSGTYECQVSTEPKISQG 140
            .|:|:|.....||::.....|.:.|....|:| ...|.|:|...|..|.|.|.||::|:|..||.
  Fly    61 KVAWLRVDTQTILSIQNHVITKNHRISISHTE-HRIWQLKIRDVQESDRGWYMCQINTDPMKSQM 124

  Fly   141 FRLNVVV--SRAKILGNAELFIKSGSDINLTCLAMQSPVPPSFIYWYKGKRV-MNYSQRGGINVI 202
            ..|:|||  .......:.::...:|.::.|||.|...|:|.  |.|.:.:.. :..|..|...|.
  Fly   125 GYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPT--ITWRREEATPILISDDGDREVF 187

  Fly   203 TERSTRTSKLLIAKATPADSGNYTCSPSSSDSASV---VVHVIN 243
               |.....|.:.:...:..|.|.|..|:....:|   |:.|:|
  Fly   188 ---SVEGQNLTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVN 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	32/92 (35%)
		IG_like	53..145	CDD:214653	32/91 (35%)
		ig	153..227	CDD:278476	16/74 (22%)
		IG_like	161..>227	CDD:214653	16/66 (24%)
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	32/90 (36%)
		Ig	39..122	CDD:299845	30/87 (34%)
		Ig	132..213	CDD:299845	17/85 (20%)
		IG_like	141..227	CDD:214653	20/90 (22%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810