DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr4 and Sdk1

DIOPT Version :9

Sequence 1:NP_001014616.2 Gene:dpr4 / 3346160 FlyBaseID:FBgn0053512 Length:323 Species:Drosophila melanogaster
Sequence 2:NP_808547.3 Gene:Sdk1 / 330222 MGIID:2444413 Length:2193 Species:Mus musculus


Alignment Length:304 Identity:88/304 - (28%)
Similarity:124/304 - (40%) Gaps:53/304 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 GGEVPPH-YWETPYSQPYFDNSSRREVTATV--GQAALLHCRVRNLGDRAVSWIRKRDLHILTVG 91
            ||||..| |.:.....|.|   ::|.|..||  |..|:|.|.|......|::|  ||..|||..|
Mouse   446 GGEVQTHTYLDVTNIAPAF---TQRPVDTTVTDGMTAVLRCEVSGAPKPAITW--KRGNHILASG 505

  Fly    92 ILTYTNDQRFQSLHSEGSDEWTLRISSPQPRDSGTYEC-QVSTEPKISQGFRLNVVVSRAKILGN 155
            .:..   .||..|.|.|     |||:....:|:|.|.| ..:||..::....| .|.:|..|:..
Mouse   506 SVRI---PRFMLLESGG-----LRIAPVFIQDAGNYTCYAANTEASVNASAML-TVWNRTSIVHP 561

  Fly   156 AE--LFIKSGSDINLTCLAMQSPVPPSFIYWYKGKRVMNYSQRGGINVITERSTRTSKLLIAKAT 218
            .|  :.|| |:...|.|.|...|.......|.|...|:..|...  .::.|:.   ..|:|::..
Mouse   562 PEDRVVIK-GTTATLCCGATHDPRTSLRYVWKKDNVVITASSSS--RIVVEKD---GSLVISQTW 620

  Fly   219 PADSGNYTC---SPSSSDSASVVVHVINGEHPAAMQHGNSSATCLRPLSSTSVPFVLATWMSMTV 280
            ..|.|:|||   |...|||.:..:.||...||.     .:....|.|..|.||..   :|    |
Mouse   621 SGDIGDYTCEIISEGGSDSRTARLEVIELPHPP-----QNLLASLSPARSHSVTL---SW----V 673

  Fly   281 ASVAWNSN-----LNINWNWSPDWRWHWNPKWNWSNLAAGLVGI 319
            .....||.     :.::.|.|| |:.|      .||:...:.|:
Mouse   674 RPFDGNSPVLYYIVQVSENNSP-WKVH------LSNVGPEMTGV 710

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr4NP_001014616.2 V-set 53..146 CDD:284989 32/95 (34%)
IG_like 53..145 CDD:214653 32/94 (34%)
ig 153..227 CDD:278476 18/75 (24%)
IG_like 161..>227 CDD:214653 16/65 (25%)
Sdk1NP_808547.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..56
Ig_2 94..169 CDD:290606
IG_like 100..169 CDD:214653
IG_like 183..263 CDD:214653
Ig 197..247 CDD:299845
IG_like 281..357 CDD:214653
IGc2 294..347 CDD:197706
I-set 368..457 CDD:254352 6/10 (60%)
Ig 388..454 CDD:143165 5/7 (71%)
I-set 462..552 CDD:254352 34/103 (33%)
Ig 476..552 CDD:299845 28/86 (33%)
I-set 557..646 CDD:254352 25/94 (27%)
Ig 562..646 CDD:299845 24/89 (27%)
FN3 650..741 CDD:238020 19/80 (24%)
fn3 753..839 CDD:278470
FN3 854..949 CDD:238020
FN3 954..1036 CDD:238020
FN3 1052..1148 CDD:238020
FN3 1158..1253 CDD:238020
FN3 1261..1349 CDD:238020
FN3 1360..1453 CDD:238020
FN3 1459..1554 CDD:238020
FN3 1562..1676 CDD:238020
FN3 1686..1779 CDD:238020
FN3 1784..1865 CDD:238020
FN3 1885..1978 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2057..2080
PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 2187..2193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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