DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr4 and Ncam2

DIOPT Version :9

Sequence 1:NP_001014616.2 Gene:dpr4 / 3346160 FlyBaseID:FBgn0053512 Length:323 Species:Drosophila melanogaster
Sequence 2:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus


Alignment Length:263 Identity:60/263 - (22%)
Similarity:102/263 - (38%) Gaps:60/263 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 GQAALLHCRVRNLGDRAVSWIRKRDLHILTVGILTYTNDQRFQSLHSEGSDEWTLRISSPQPRDS 124
            |:.|.:.|||.:....||||:...: .:.|:      .|.||..|.:.     .|:|.:....|.
  Rat   129 GEDAEVVCRVSSSPAPAVSWLYHNE-EVTTI------PDNRFAVLANN-----NLQILNINKSDE 181

  Fly   125 GTYECQVSTEPKISQGFR-----LNV----VVSRAKILGNAELFIKSGSDINLTCLAMQSPVPPS 180
            |.|.|:...|.:....||     :||    |:.:......||    .|.::.|||.|..||.|. 
  Rat   182 GIYRCEGR
VEARGEIDFRDIIVIVNVPPAIVMPQKSFNATAE----RGEEMTLTCKASGSPDPA- 241

  Fly   181 FIYWYKGKRVM----NYSQRGGINVITERSTRTSKLLIAKATPADSGNYTCSPSSSDSAS----- 236
             |.|::..:::    .|..:|....:|.|:      :|.|    |.|:|.|..::.....     
  Rat   242 -ISWFRNGKLIEENEKYILKGSNTELTVRN------IINK----DGGSYVCKATNKAGEDQKQAF 295

  Fly   237 ----VVVHVINGEHPAAMQHGNSSATCLRPLSSTSVPFVLATWMSMTVASVAWNSNLNINWNWSP 297
                |..|::..::....::|:.:..|    .:...|....|| ...:..|.::..     :.||
  Rat   296 LQVFVQPHILQLKNETTSENGHVTLIC----EAEGEPVPEITW-KRAIDGVTFSEG-----DKSP 350

  Fly   298 DWR 300
            |.|
  Rat   351 DGR 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr4NP_001014616.2 V-set 53..146 CDD:284989 25/94 (27%)
IG_like 53..145 CDD:214653 23/89 (26%)
ig 153..227 CDD:278476 21/77 (27%)
IG_like 161..>227 CDD:214653 19/69 (28%)
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452
Ig strand G 104..107 CDD:409452
IGc2 128..189 CDD:197706 20/71 (28%)
Ig strand B 130..139 CDD:409353 3/8 (38%)
Ig strand C 145..153 CDD:409353 4/7 (57%)
Ig strand C' 156..159 CDD:409353 1/8 (13%)
Ig strand D 162..167 CDD:409353 2/4 (50%)
Ig strand E 168..175 CDD:409353 2/11 (18%)
IgI_1_MuSK 209..298 CDD:409562 23/104 (22%)
Ig strand B 228..232 CDD:409562 1/3 (33%)
Ig strand C 241..245 CDD:409562 1/5 (20%)
Ig strand E 264..268 CDD:409562 0/3 (0%)
Ig strand F 278..283 CDD:409562 2/4 (50%)
Ig strand G 291..294 CDD:409562 0/2 (0%)
Ig 300..397 CDD:416386 12/64 (19%)
Ig strand A 300..305 CDD:409353 2/4 (50%)
Ig strand A' 309..313 CDD:409353 0/3 (0%)
Ig strand B 317..325 CDD:409353 1/11 (9%)
Ig strand C 331..337 CDD:409353 2/6 (33%)
Ig strand C' 340..343 CDD:409353 1/2 (50%)
Ig strand D 353..359 CDD:409353 1/1 (100%)
Ig strand E 362..368 CDD:409353
Ig strand F 376..384 CDD:409353
Ig strand G 387..397 CDD:409353
Ig_3 401..479 CDD:404760
Ig strand B 418..422 CDD:409353
Ig strand C 431..435 CDD:409353
Ig strand E 458..462 CDD:409353
Ig strand F 472..477 CDD:409353
Ig strand G 486..489 CDD:409353
FN3 496..588 CDD:238020
fn3 594..678 CDD:394996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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