DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr4 and Tyro3

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_058788.1	Gene:	Tyro3 / 25232	RGDID:	3923	Length:	880	Species:	Rattus norvegicus

Alignment Length:	253	Identity:	60/253 - (23%)
Similarity:	100/253 - (39%)	Gaps:	55/253 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 EVTATVGQAALLHCRVRNLGDRAVSWIRKRDLHILTVGILTYTNDQRFQSLHSEGSDEW--TLRI 116
            ::|.:.||...|:|.|..:.|..:.|::.        |.:.....|...|:..:   .|  .|.:
  Rat    41 KMTVSQGQPVKLNCSVEGMDDPDIHWMKD--------GAVVQNASQVSISISEQ---NWIGLLSL 94

  Fly   117 SSPQPRDSGTYECQV--STEPKISQGFRLNVVVSRAKILGNAELFIKSGSDINLTCLAMQSPVPP 179
            .|.:..|:|.|.|||  ..|.||||...|.|.......:...:|.:.......|:|.|:..|.|.
  Rat    95 KSAERSDAGLYWCQVKDGEETKISQSVWLTVEGVPFFTVEPKDLAVPPNVPFQLSCEAVGPPEPV 159

  Fly   180 SFIYWYKGKRVMNYSQRGG-------INV--ITER-------------STRTSKLLIAKATPADS 222
            : |:|::|.     ::.||       :||  :|:|             :|....::..:|.||..
  Rat   160 T-IFWWRGP-----TKVGGPASSPSVLNVTGVTQRTEFSCEAHNIKGLATSRPAIIRLQAPPAAP 218

  Fly   223 GNYTCSPSSSDSASVVVHVINGEHPAAMQHGNSSATCLRPLSSTSVPFVLATWMSMTV 280
            .|.|.:..||.:|||.  .:.|....|:.|     :|     :..|......|.::.|
  Rat   219 FNITVTTISSSNASVA--WVPGADGLALLH-----SC-----TVQVAHAPGEWEALAV 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	26/95 (27%)
		IG_like	53..145	CDD:214653	26/94 (28%)
		ig	153..227	CDD:278476	20/95 (21%)
		IG_like	161..>227	CDD:214653	19/87 (22%)
Tyro3	NP_058788.1	IG_like	39..125	CDD:214653	26/94 (28%)
		IGc2	46..111	CDD:197706	19/75 (25%)
		Ig2_Tyro3_like	131..209	CDD:143226	16/83 (19%)
		IG_like	135..204	CDD:214653	15/74 (20%)
		FN3	215..307	CDD:238020	16/62 (26%)
		fn3	315..396	CDD:278470
		PTKc_Tyro3	498..781	CDD:270659
		Pkinase_Tyr	508..776	CDD:285015
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	804..827
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	842..864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910