DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr4 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	310	Identity:	68/310 - (21%)
Similarity:	120/310 - (38%)	Gaps:	90/310 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 WLLLFLDCGMVGGEVPPHYWETPYSQPYFDNSSRREVTATVGQAALLHCRVRNLGDRAVSWIRKR 83
            |:.|.::       .||.:.|||   |.:       :.|..|.:..:.|.........|:|:::.
Mouse   132 WVHLTIN-------APPTFTETP---PQY-------IEAKEGGSITMTCTAFGNPKPIVTWLKEG 179

  Fly    84 DLHILTVGILTYTNDQRFQSLHSEGSDEWTLRISSPQPRDSGTYECQ--------VSTEPKISQG 140
            .|    :|.     ..::|.  |:||    |.::|....|.|.|.|:        |.|...:.||
Mouse   180 TL----LGA-----SAKYQV--SDGS----LTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQG 229

  Fly   141 --FRLNVVVSRAKILGNAELFIKSGSDINLTCLAMQSPVPPSFIYWYKGKRVMNYSQRG---GIN 200
              |    :||..:     .:.:....|..|||.|...|...::.::::.:.|  |.|..   .:.
Mouse   230 PPF----IVSPPE-----NITVNISQDALLTCRAEAYPGNLTYTWYWQDENV--YFQNDLKLRVR 283

  Fly   201 VITERSTRTSKLLIAKATPADSGNYTCSPSS----SDSASVVVHVINGEHPAAMQHGNSSATCLR 261
            ::.:     ..|:|.:..|.|:|.|||.||:    |.|||..:.|   ::||.:.:       :.
Mouse   284 ILID-----GTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTV---QYPARVLN-------MP 333

  Fly   262 PLSSTSVPFVLATWMSMTVAS------VAWNSN-------LNINWNWSPD 298
            |:  ..||..:..::...|.:      |.||.:       .|:.|....|
Mouse   334 PV--IYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMED 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	22/102 (22%)
		IG_like	53..145	CDD:214653	22/101 (22%)
		ig	153..227	CDD:278476	15/76 (20%)
		IG_like	161..>227	CDD:214653	15/68 (22%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273
		I-set	141..227	CDD:369462	24/110 (22%)
		Ig	231..323	CDD:386229	26/107 (24%)
		Ig	<355..416	CDD:386229	6/27 (22%)
		Ig	440..504	CDD:319273
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900