DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr4 and Iglon5

DIOPT Version :9

Sequence 1:NP_001014616.2 Gene:dpr4 / 3346160 FlyBaseID:FBgn0053512 Length:323 Species:Drosophila melanogaster
Sequence 2:NP_001157990.1 Gene:Iglon5 / 210094 MGIID:2686277 Length:336 Species:Mus musculus


Alignment Length:346 Identity:78/346 - (22%)
Similarity:118/346 - (34%) Gaps:128/346 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 SQPYFDNSSRREVTATVGQAALLHCRVRNLGDRAVSWIRKRDLHILTVGILTYTNDQRFQSLHSE 107
            ||....:|.....|...|..|.|.|.:.....| |:|:.:.  :||..|...:|:|.|.:.|.:.
Mouse    30 SQSLEFSSPADNYTVCEGDNATLSCFIDEHVTR-VAWLNRS--NILYAGNDRWTSDPRVRLLINT 91

  Fly   108 GSDEWTLRISSPQPRDSGTYECQVST--EPKISQGFRLNVVVSRAKILG-NAELFIKSGSDINLT 169
             .:|:::.|:.....|.|.|.|...|  :|..:|.:.  :|...|:|:. ::.:.:..|.::||.
Mouse    92 -PEEFSILITQVGLGDEGLYTCSFQTRHQPYTTQVYL--IVHVPARIVNISSPVAVNEGGNVNLL 153

  Fly   170 CLAMQSP---------------------------------------------------------- 176
            |||:..|                                                          
Mouse   154 CLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPP 218

  Fly   177 ------------------------VPPSFIYWYKGKRVMNYSQRGGINVITERSTRTSKLLIAKA 217
                                    |||:...|||..|:::.....|:.|.||| || |.||.|..
Mouse   219 TITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGSAEGLKVQTER-TR-SMLLFANV 281

  Fly   218 TPADSGNYTCSPSSSDSASVVVHVINGEHPAAMQHGNSSAT--CLRPLS-STSVPFVLATWMSMT 279
            :....|||||.                   ||.:.|.|||:  .|||.| ..|.|....   .:|
Mouse   282 SARHYGNYTCR-------------------AANRLGASSASMRLLRPGSLENSAPRPPG---PLT 324

  Fly   280 VASVAWNSNLNINWNWSPDWR 300
            :.|.       ::|.|   ||
Mouse   325 LLSA-------LSWLW---WR 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr4NP_001014616.2 V-set 53..146 CDD:284989 24/94 (26%)
IG_like 53..145 CDD:214653 24/93 (26%)
ig 153..227 CDD:278476 28/156 (18%)
IG_like 161..>227 CDD:214653 28/147 (19%)
Iglon5NP_001157990.1 Ig 41..129 CDD:416386 24/93 (26%)
Ig strand A' 41..46 CDD:409353 1/4 (25%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 0/3 (0%)
FR2 61..68 CDD:409353 3/7 (43%)
Ig strand C 61..67 CDD:409353 3/6 (50%)
CDR2 69..79 CDD:409353 3/11 (27%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 10/35 (29%)
Ig strand D 84..91 CDD:409353 2/6 (33%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 2/10 (20%)
FR4 122..129 CDD:409353 1/8 (13%)
Ig strand A 132..137 CDD:409353 2/4 (50%)
Ig_3 134..199 CDD:404760 8/64 (13%)
Ig strand A' 140..145 CDD:409353 0/4 (0%)
Ig strand B 148..157 CDD:409353 4/8 (50%)
Ig strand C 163..167 CDD:409353 0/3 (0%)
Ig strand D 174..177 CDD:409353 0/2 (0%)
Ig strand E 178..183 CDD:409353 0/4 (0%)
Ig strand F 191..199 CDD:409353 0/7 (0%)
Ig_3 217..295 CDD:404760 24/98 (24%)
putative Ig strand A 218..224 CDD:409353 0/5 (0%)
Ig strand B 234..238 CDD:409353 0/3 (0%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 4/23 (17%)
Ig strand G 301..304 CDD:409353 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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