DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr4 and zig-2

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_510069.1	Gene:	zig-2 / 192087	WormBaseID:	WBGene00006979	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	172	Identity:	40/172 - (23%)
Similarity:	66/172 - (38%)	Gaps:	53/172 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 FIKSGSDINLT--------CLAMQSPVPPSFIYW------YKGKRVMNYSQRGGINVITERSTRT 209
            |.::.:|.|:|        |.|..:|:|.  |||      .:|:...|..:    |::.:....:
Worm    35 FTRTPNDSNVTFGEKFVLSCGANGAPLPS--IYWELNGMRIQGEETSNVYE----NILNDGKQVS 93

  Fly   210 SKLLIAK------ATPADSGNYTCSPSSSDSASVVVHVING----EHPAAMQHGNSSATCLRPLS 264
            :..:::.      ||..:||.|.|.            :.||    ||.|.:..|.:...|  .|:
Worm    94 NAAMVSSHYRIPCATARNSGAYKCI------------IDNGLTKLEHVAKVFVGGNKTNC--ALN 144

  Fly   265 STSVPFVLATWMSMTVASVAWNSN----LNINWNWSPDWRWH 302
            ....||:     ||||......||    |:.....:.:|.||
Worm   145 DNGAPFI-----SMTVDFRLEISNNAVALSCRSETATEWSWH 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989
		IG_like	53..145	CDD:214653
		ig	153..227	CDD:278476	19/87 (22%)
		IG_like	161..>227	CDD:214653	18/85 (21%)
zig-2	NP_510069.1	I-set	34..134	CDD:254352	25/116 (22%)
		Ig	34..121	CDD:299845	20/103 (19%)
		Ig	<179..232	CDD:299845	2/3 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900