DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr4 and rig-3

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_509155.1	Gene:	rig-3 / 180958	WormBaseID:	WBGene00004370	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	51/253 - (20%)
Similarity:	80/253 - (31%)	Gaps:	85/253 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 YSQPYFDNSSRREVTATVGQA--ALLHCRVRNL-----------GDRAVSWIRKRDLHILTVGIL 93
            |:.|.|:.....:.|......  |:::|.|.:.           ||..:....|.::.: .||:
Worm   244 YTLPEFETEESVQYTVIDNHVRDAIIYCNVTHSFPPVRHYTFYHGDEEIKMSDKFNIFV-NVGV- 306

  Fly    94 TYTNDQRFQSLHSEGSDEWTLRISSPQPRDSGTYECQVS------------------TEPKIS-- 138
                        |:|:.   |:|.:....|.|||:|:.:                  .|||::
Worm   307 ------------SQGAH---LKIHNVNENDLGTYKCEANNIKAKSYHTIHLREANAPAEPKVTLI 356

  Fly   139 -----------------QGFRLNVVVSRAKILGNAELFIKSGSDIN-----LTCLAMQSPVPPSF 181
                             ....:..|..|....|.||....|..||:     ...:.||..:....
Worm   357 EDKRHSIIWKVESIDRDPDLPMTAVEIRHLRAGTAEASGVSDEDISDAYWKSHSIFMQRNIKDDG 421

  Fly   182 IYWYKGKR-----VMNYSQRGGINVITERSTRTSKLLIAKATPADSGNYTCSPSSSDS 234
            ||...|.|     |..:.|      |.|.....|.:|.||.  .|..:.....|:|||
Worm   422 IYEINGLRHGHEYVWRFRQ------INEAGFGDSVVLRAKT--LDDHDLEMMDSASDS 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	21/142 (15%)
		IG_like	53..145	CDD:214653	21/141 (15%)
		ig	153..227	CDD:278476	21/83 (25%)
		IG_like	161..>227	CDD:214653	18/75 (24%)
rig-3	NP_509155.1	IG_like	48..142	CDD:214653
rig-3	NP_509155.1	Ig	267..341	CDD:319273	17/90 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900