DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr4 and ntm

DIOPT Version :9

Sequence 1:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	64/315 - (20%)
Similarity:	107/315 - (33%)	Gaps:	123/315 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 VTATVGQAALLHCRVRNLGDRAVSWIRKRDLHILTVGILTYTNDQRFQSLHSEGSDEWTLRISSP 119
            ||...|.:|:|.|.|.|...| |:|:.:..  ||..|...::.|.|...|.:..| ::::.|.:.
Frog    46 VTVRQGDSAILRCTVDNRVTR-VAWLNRST--ILYTGNDKWSIDPRVVLLANTKS-QYSIEIQNV 106

  Fly   120 QPRDSGTYECQVSTE--PKISQGFRLNVVVS-RAKILG-NAELFIKSGSDINLTCLAMQSPVP-- 178
            ...|.|.|.|.|.|:  ||.|   |::::|. ..:|:. ::.:.:..||:::|.|:|...|.|
Frog   107 DIYDEGPYTCSVQTDNHPKTS---RVHLIVQVPPRIVDISSSIAVNEGSNVSLICIANGRPEPVV 168

  Fly   179 ------------------------------------------------------PSFI------- 182
                                                                  |.:|
Frog   169 NWRYLSPKARGFVSEDEYLEITGITREQSGIYECSASNDVSAPDVRRVKLTVNYPPYILDAQNIG 233

  Fly   183 ---------------------YWYKGKRVMNYSQRGGINVITERSTRTSKLLIAKATPADSGNYT 226
                                 :|||..:.::.|.||   |..|.....|::.....:..|.||||
Frog   234 APLGHRGILQCEASAVPAADFFWYKEDKRLSDSWRG---VKVENRETISRVTFLNVSEQDYGNYT 295

  Fly   227 C-----------------------SPSSSDSASVVVHVINGEHPAAMQHGNSSAT 258
            |                       ||...:.::..:..:.|  |.|:..|||.:|
Frog   296 CMAKNLLGHSNASIILFELFQSTSSPLLQEESTAALTPLKG--PGAVHDGNSGST 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	29/92 (32%)
		IG_like	53..145	CDD:214653	29/91 (32%)
		ig	153..227	CDD:278476	22/158 (14%)
		IG_like	161..>227	CDD:214653	22/149 (15%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	29/93 (31%)
		IG_like	45..133	CDD:214653	29/93 (31%)
		IG_like	143..220	CDD:214653	7/76 (9%)
		IGc2	150..209	CDD:197706	7/58 (12%)
		ig	227..311	CDD:278476	15/86 (17%)
		IG_like	230..311	CDD:214653	15/83 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000