Protein Alignment CG32547 and ckr-1

DIOPT Version :10

• Sequence 1: NP_728174.2
• Gene: CG32547 / 3346150
• FlyBaseID: FBgn0052547
• Length: 1008
• Species: Drosophila melanogaster
• Sequence 2: NP_491918.3
• Gene: ckr-1 / 188774
• WormBaseID: WBGene00020712
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 416
• Identity: 84/416 - (20%)
• Similarity: 154/416 - (37%)
• Gaps: 98/416 - (23%)

  Fly    97 IKSVYWLFLIQYAALALLGVVLNVIIVVYIM--YHRLYKDVTHAFIINLALCHFVQCALVLPVSL 159
            |.|::.|.||    |:|||   |.|:::.|:  .|| .:.:|:.:::|||....::..:.:|.:|
 Worm    16 ISSIFLLCLI----LSLLG---NAIVILTILGKSHR-SRSITNFYLLNLAFADLLRSIICIPSTL 72

  Fly   160 MVMLIQNWIFGQFLCFFLPMLQDIPLHVAMISHILIAWDRMRWLNDPLKGRL------------- 211
            :..|.|.|:.|..:|..:..||.:.:..:..:..:||.:|...:..||:.|.
 Worm    73 LGELTQCWLLGAAMCKIVAFLQPVGVCASAYTLAVIAIERYYAICRPLESRKWQTKKRALITISL 137

  Fly   212 -------------------PGFVCCCATWLTGMVIALPYPIYTIYVELGDYMPQLSGIGL----- 252
                               ||...|.:|  .|.::...|.:|..:..|  ::|....:||
 Worm   138 VWCFSFSANLTSLFLYDANPGKFTCDST--KGPLVDFIYQLYLTFTLL--FVPLALMVGLYGNVI 198

  Fly   253 ----CVVN-----LMDDMQEYT---RGLFLLMYCGPAILLSYLYIRTSQELRPPDGPFAVMMYEH 305
                ..:|     :...|.|.|   |..|           |..::...|.:...........::.
 Worm   199 ITLNTAINSDHPTVEQQMIEKTLPSRASF-----------SDWFVSAVQRVPSMKVVSKTFQFKE 252

  Fly   306 RADLRMRQRNSSTSSVEPRHLSGGGVAGLSNGGGNSARSYDLYSAELDVHREK--RKQRNFGSMA 368
            :..|.:.|  :|..||.|...|.........|      |:|:.......::||  ..::....|.
 Worm   253 KNSLSIPQ--TSGLSVRPSRSSFSSFFSTPRG------SFDVTMLLRSTNQEKILIAKKKVTRML 309

  Fly   369 ATQVV----CMCP----LMILRFARLSLEETYENAKHFDFTYLMFVWVAFLPTVIFPCI----YA 421
            .|.|:    |..|    .::||.|.|:..:.:....:...|  :..:::.|...|..|.    :.
 Worm   310 ITLVIVFAFCWVPSYLYWLLLRMAELAATDLWNPGLNSSLT--IMTYISSLANPITYCFMNKSFR 372

  Fly   422 SQILPRDEQERLRGYFRLSSKRKQKS 447
            |.:|.....:..|...|.|:...:||
 Worm   373 SSVLAYCRPKPKRPLTRCSALPTRKS 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32547	NP_728174.2	7tm_classA_rhodopsin-like	104..421	CDD:410626	74/381 (19%)
		TM helix 1	104..129	CDD:410626	9/26 (35%)
		TM helix 2	136..162	CDD:410626	6/25 (24%)
		TM helix 3	174..204	CDD:410626	6/29 (21%)
		TM helix 4	213..231	CDD:410626	4/17 (24%)
		TM helix 5	261..286	CDD:410626	6/27 (22%)
		TM helix 6	355..385	CDD:410626	9/39 (23%)
		TM helix 7	399..421	CDD:410626	4/25 (16%)
ckr-1	NP_491918.3	7tmA_CCKR-like	30..375	CDD:320124	70/373 (19%)
		TM helix 2	49..75	CDD:320124	6/25 (24%)
		TM helix 3	87..117	CDD:320124	6/29 (21%)
		TM helix 4	131..149	CDD:320124	0/17 (0%)
		TM helix 5	171..196	CDD:320124	6/26 (23%)
		TM helix 6	300..330	CDD:320124	5/29 (17%)
		TM helix 7	343..368	CDD:320124	4/26 (15%)