DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33557 and Twist1

DIOPT Version :9

Sequence 1:	NP_001014730.1	Gene:	CG33557 / 3346145	FlyBaseID:	FBgn0053557	Length:	150	Species:	Drosophila melanogaster
Sequence 2:	NP_035788.1	Gene:	Twist1 / 22160	MGIID:	98872	Length:	206	Species:	Mus musculus

Alignment Length:	127	Identity:	39/127 - (30%)
Similarity:	59/127 - (46%)	Gaps:	15/127 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 AQDSNSSGSASGSGAAADSEDSQIGQEANPGGQENQGNHRRRPPRQKINARERYRTFNVNSAYEA 83
            ||......||.|.|..........|..::.||...|.....:..|...|.|||.||.::|.|:.|
Mouse    70 AQGKRGKKSAGGGGGGGAGGGGGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAA 134

  Fly    84 LRNLIPTEPMNRKLSKIEIIRLASSYITHLSSTLETGTECQPCLLHKYESEGITRRISICTF 145
            ||.:|||.|.: |||||:.::||:.||..|...|              :|:.:..:::.|::
Mouse   135 LRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVL--------------QSDELDSKMASCSY 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33557	NP_001014730.1	HLH	67..119	CDD:197674	26/51 (51%)
Twist1	NP_035788.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..109		10/38 (26%)
		HLH	113..163	CDD:306515	25/50 (50%)
		Sufficient for transactivation activity	165..195		3/31 (10%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839656
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840