Protein Alignment CG33521 and CSRP3

DIOPT Version :10

• Sequence 1: NP_001014703.1
• Gene: CG33521 / 3346141
• FlyBaseID: FBgn0250819
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_003467.1
• Gene: CSRP3 / 8048
• HGNCID: 2472
• Length: 194
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 49/225 - (21%)
• Similarity: 80/225 - (35%)
• Gaps: 62/225 - (27%)

  Fly    80 CHQCKKPVYKMEEVILSLKTATTIFHKTCLRCKDCGKHLKFDSYNVHDGSLYCSMHFKLIFAPKV 144
            |..|:|.||..||:..:.::    |||||..|..|.|.|...:...|:..:||.:.:...:.||.
Human    10 CGACEKTVYHAEEIQCNGRS----FHKTCFHCMACRKALDSTTVAAHESEIYCKVCYGRRYGPKG 70

  Fly   145 V--------------------YEEFTPRKAELIIRENQPIKLPPDVAKASDKPSLGLDELQELNL 189
            :                    ::: :|:.|..:...| |.|......::...|..|      .::
Human    71 IGYGQGAGCLSTDTGEHLGLQFQQ-SPKPARSVTTSN-PSKFTAKFGESEKCPRCG------KSV 127

  Fly   190 RSKFKVFENGYEEHNNNLRERQDIAITHSKSIQSTLTKFHGLGIPNSELTKLDDKNSDNNSDGDG 254
            .:..||...|...|....|    .||. .||::||                       |.:|.||
Human   128 YAAEKVMGGGKPWHKTCFR----CAIC-GKSLEST-----------------------NVTDKDG 164

  Fly   255 DMNF-MCLKKEIERETPVGLGEAMNDIRSK 283
            ::.. :|..|.. ..|.:|.|.....:..|
Human   165 ELYCKVCYAKNF-GPTGIGFGGLTQQVEKK 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33521	NP_001014703.1	LIM_Mical_like_2	80..136	CDD:188829	19/55 (35%)
CSRP3	NP_003467.1	Interaction with TCAP. /evidence=ECO:0000269|PubMed:12507422	1..5
		LIM1_CRP3	9..62	CDD:188865	19/55 (35%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:P50463, ECO:0000255	64..69		0/4 (0%)
		Interaction with CLF2 and isoform 2. /evidence=ECO:0000269|PubMed:19752190, ECO:0000269|PubMed:24860983	94..105		2/11 (18%)
		LIM2_CRP3	120..173	CDD:188866	18/86 (21%)