DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33521 and Csrp3

DIOPT Version :9

Sequence 1:	NP_001014703.1	Gene:	CG33521 / 3346141	FlyBaseID:	FBgn0250819	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	NP_476485.2	Gene:	Csrp3 / 117505	RGDID:	71092	Length:	194	Species:	Rattus norvegicus

Alignment Length:	225	Identity:	49/225 - (21%)
Similarity:	79/225 - (35%)	Gaps:	62/225 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 CHQCKKPVYKMEEVILSLKTATTIFHKTCLRCKDCGKHLKFDSYNVHDGSLYCSMHFKLIFAPKV 144
            |..|.|.||..||:..:.::    |||||..|..|.|.|...:...|:..:||.:.:...:.||.
  Rat    10 CGACDKTVYHAEEIQCNGRS----FHKTCFHCMACRKALDSTTVAAHESEIYCKVCYGRKYGPKG 70

  Fly   145 V--------------------YEEFTPRKAELIIRENQPIKLPPDVAKASDKPSLGLDELQELNL 189
            :                    ::: :|:.|......| |.|......::...|..|      .::
  Rat    71 IGFGQGAGCLSTDTGEHLGLQFQQ-SPKPARAATTSN-PSKFSAKFGESEKCPRCG------KSV 127

  Fly   190 RSKFKVFENGYEEHNNNLRERQDIAITHSKSIQSTLTKFHGLGIPNSELTKLDDKNSDNNSDGDG 254
            .:..||...|...|....|    .||. .||::||                       |.:|.||
  Rat   128 YAAEKVMGGGKPWHKTCFR----CAIC-GKSLEST-----------------------NVTDKDG 164

  Fly   255 DMNF-MCLKKEIERETPVGLGEAMNDIRSK 283
            ::.. :|..|.. ..|.:|.|...:.:..|
  Rat   165 ELYCKVCYAKNF-GPTGIGFGGLTHQVEKK 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33521	NP_001014703.1	LIM_Mical_like_2	80..136	CDD:188829	19/55 (35%)
Csrp3	NP_476485.2	Interaction with TCAP. /evidence=ECO:0000250\|UniProtKB:P50461	1..5
		LIM1_CRP3	9..62	CDD:188865	19/55 (35%)
		Nuclear localization signal. /evidence=ECO:0000255, ECO:0000305\|PubMed:19376126	64..69		0/4 (0%)
		Interaction with CLF2. /evidence=ECO:0000250\|UniProtKB:P50461	94..105		2/11 (18%)
		LIM2_CRP3	120..173	CDD:188866	18/86 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910