Protein Alignment Pgk and Pgk1

DIOPT Version :9

• Sequence 1: NP_001259956.1
• Gene: Pgk / 33461
• FlyBaseID: FBgn0250906
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_445743.2
• Gene: Pgk1 / 24644
• RGDID: 619878
• Length: 417
• Species: Rattus norvegicus
• Alignment Length: 412
• Identity: 292/412 - (70%)
• Similarity: 341/412 - (82%)
• Gaps: 1/412 - (0%)

  Fly     4 NKLSIENLDLAGKRVLMRVDFNVPIKEGKITSNQRIVAALDSIKLALSKKAKSVVLMSHLGRPDG 68
            |||:::.||:.||||:||||||||:|..:||:||||.||:.|||..|...|||||||||||||||
  Rat     5 NKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDG 69

  Fly    69 -NKNIKYTLAPVAAELKTLLGQDVIFLSDCVGSEVEAACKDPAPGSVILLENVRFYVEEEGKGLD 132
             ....||:|.|||||||:|||:||:||.||||||||.||.:||.|:||||||:||:|||||||.|
  Rat    70 VPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGSEVENACANPAAGTVILLENLRFHVEEEGKGKD 134

  Fly   133 ASGGKVKADPAKVKEFRASLAKLGDVYVNDAFGTAHRAHSSMMGDGFEQRAAGLLLNKELKYFSQ 197
            |||.||||:|||:..|||||:|||||||||||||||||||||:|....|:|.|.|:.|||.||::
  Rat   135 ASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAK 199

  Fly   198 ALDKPPNPFLAILGGAKVADKIQLIENLLDKVNEMIIGGGMAFTFLKVLNNMKIGGSLFDEEGSK 262
            ||:.|..||||||||||||||||||.|:||||||||||||||||||||||||:||.||:||||:|
  Rat   200 ALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLYDEEGAK 264

  Fly   263 IVEKLVEKAKKNNVQLHLPVDFVCGDKFAENAAVSEATVEAGIPDGHMGLDVGPKTRELFAAPIA 327
            ||:.|:.||:||.|::.||||||..|||.|||...:|||.:|||.|.||||.|.::.:.:|..:|
  Rat   265 IVKDLMAKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGTESSKKYAEAVA 329

  Fly   328 RAKLIVWNGPPGVFEFPNFANGTKSIMDGVVAATKNGTVSIIGGGDTASCCAKWNTEALVSHVST 392
            |||.||||||.||||:..||.||||:||.||.||..|.::||||||||:||||||||..||||||
  Rat   330 RAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVST 394

  Fly   393 GGGASLELLEGKTLPGVAALTS 414
            ||||||||||||.||||.||::
  Rat   395 GGGASLELLEGKVLPGVDALSN 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgk	NP_001259956.1	Phosphoglycerate_kinase	1..414	CDD:294132	292/410 (71%)
Pgk1	NP_445743.2	PTZ00005	3..416	CDD:173310	292/410 (71%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:Q7SIB7	24..26		1/1 (100%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:Q7SIB7	63..66		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338262
Domainoid	1	1.000	554	1.000	Domainoid score	I235
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21542
Inparanoid	1	1.050	574	1.000	Inparanoid score	I1012
OMA	1	1.010	-	-		QHG60610
OrthoDB	1	1.010	-	-		D367407at33208
OrthoFinder	1	1.000	-	-		FOG0001721
OrthoInspector	1	1.000	-	-		otm45669
orthoMCL	1	0.900	-	-		OOG6_100440
Panther	1	1.100	-	-	LDO	PTHR11406
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910