Protein Alignment Pgk and Pgk2

DIOPT Version :9

• Sequence 1: NP_001259956.1
• Gene: Pgk / 33461
• FlyBaseID: FBgn0250906
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_112467.2
• Gene: Pgk2 / 18663
• MGIID: 97563
• Length: 417
• Species: Mus musculus
• Alignment Length: 411
• Identity: 284/411 - (69%)
• Similarity: 339/411 - (82%)
• Gaps: 1/411 - (0%)

  Fly     5 KLSIENLDLAGKRVLMRVDFNVPIKEGKITSNQRIVAALDSIKLALSKKAKSVVLMSHLGRPDG- 68
            ||:::.:||.||||:||||||||:|..:||:||||.||:.|||..|...|||||||||||||||
Mouse     6 KLTLDKVDLKGKRVIMRVDFNVPMKNNQITNNQRIKAAIPSIKHCLDNGAKSVVLMSHLGRPDGI 70

  Fly    69 NKNIKYTLAPVAAELKTLLGQDVIFLSDCVGSEVEAACKDPAPGSVILLENVRFYVEEEGKGLDA 133
            ....||:|.|||.|||:||.:|||||.||||.|||.||.:|..||:|||||:||:|||||||.|:
Mouse    71 PMPDKYSLEPVADELKSLLNKDVIFLKDCVGPEVEQACANPDNGSIILLENLRFHVEEEGKGKDS 135

  Fly   134 SGGKVKADPAKVKEFRASLAKLGDVYVNDAFGTAHRAHSSMMGDGFEQRAAGLLLNKELKYFSQA 198
            ||.|:.||||||:.|:|||:||||||||||||||||||||.:|....|:|:|.|:.|||.|||:|
Mouse   136 SGKKISADPAKVEAFQASLSKLGDVYVNDAFGTAHRAHSSTVGVNLPQKASGFLMKKELDYFSKA 200

  Fly   199 LDKPPNPFLAILGGAKVADKIQLIENLLDKVNEMIIGGGMAFTFLKVLNNMKIGGSLFDEEGSKI 263
            |:||..|||||||||||.||||||:|:|||||.||||||||:||||.|.||:||.|||||||:.|
Mouse   201 LEKPERPFLAILGGAKVKDKIQLIKNMLDKVNFMIIGGGMAYTFLKELKNMQIGASLFDEEGATI 265

  Fly   264 VEKLVEKAKKNNVQLHLPVDFVCGDKFAENAAVSEATVEAGIPDGHMGLDVGPKTRELFAAPIAR 328
            |::::|||:||.|::..|||||.||||.|||.|.:||:|:|||.|.||||.||::.::.|..:|:
Mouse   266 VKEIMEKAEKNGVKIVFPVDFVTGDKFDENAKVGQATIESGIPSGWMGLDCGPESIKINAQIVAQ 330

  Fly   329 AKLIVWNGPPGVFEFPNFANGTKSIMDGVVAATKNGTVSIIGGGDTASCCAKWNTEALVSHVSTG 393
            |||||||||.||||:..||.|||::||.||.||.||.|:||||||||:|||||.||..|||||||
Mouse   331 AKLIVWNGPIGVFEWDAFAKGTKALMDEVVKATSNGCVTIIGGGDTATCCAKWGTEDKVSHVSTG 395

  Fly   394 GGASLELLEGKTLPGVAALTS 414
            |||||||||||.||||.||::
Mouse   396 GGASLELLEGKILPGVEALSN 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgk	NP_001259956.1	Phosphoglycerate_kinase	1..414	CDD:294132	284/409 (69%)
Pgk2	NP_112467.2	PTZ00005	3..416	CDD:173310	284/409 (69%)
		Substrate binding	24..26		1/1 (100%)
		Substrate binding	63..66		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834681
Domainoid	1	1.000	550	1.000	Domainoid score	I251
eggNOG	1	0.900	-	-		E1_COG0126
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	571	1.000	Inparanoid score	I1053
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60610
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001721
OrthoInspector	1	1.000	-	-		otm43596
orthoMCL	1	0.900	-	-		OOG6_100440
Panther	1	1.100	-	-	O	PTHR11406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.760