Protein Alignment Cwc25 and cwc25

DIOPT Version :10

• Sequence 1: NP_608705.1
• Gene: Cwc25 / 33460
• FlyBaseID: FBgn0031452
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_998627.1
• Gene: cwc25 / 406771
• ZFINID: ZDB-GENE-040426-2817
• Length: 393
• Species: Danio rerio
• Alignment Length: 530
• Identity: 166/530 - (31%)
• Similarity: 242/530 - (45%)
• Gaps: 146/530 - (27%)

  Fly     1 MGGGDLNLKKSWHPHTMKNQERVWKAEEQAKMEERKLQDLRKEINEERDREELRRLGESSGVLSN 65
            ||||||||||||||.|:||.|||||||::.:.|.:|:::|:||:.|||.|||:.|..:.:|.:..
Zfish     1 MGGGDLNLKKSWHPQTLKNIERVWKAEQKHEAERKKIEELQKELKEERAREEITRFAQETGAVKK 65

  Fly    66 NGGAAGEAKLEWMYKNSTELINREEYLLGRKIDKSFETLQAEESRQEQNTVGLKQTINHVEHDCV 130
            .     :.:|:|||:..:..|:||||||||.|||.. |.|.|:  ||...        ..|...:
Zfish    66 K-----DDRLDWMYQGPSGQISREEYLLGRPIDKQI-TQQYED--QESGP--------SAETGLL 114

  Fly   131 PFSIRTYRNVQSNEQVDIQRKTLEDPLMLIKQREMESRRKLLENPVKLKEIHRILKTEQEQKAAE 195
            |.||....:..|..  |:..|..||||..|::||.|.:|.:|.||||:|||.::|:...|:   |
Zfish   115 PGSIFNPSSAASTN--DMAAKIREDPLFEIRKREEEKKRGVLTNPVKMKEIQKMLRQNLEK---E 174

  Fly   196 GKKKNKKNKKSKKSKKKKKNRRSSNEESSDSESNDSDDDLDRKLARQVSKLKGDQGDLKLDKLLD 260
            .|||.||.||.||.|:|.|..|..:..|.|          :|:
Zfish   175 KKKKRKKEKKEKKEKRKDKEHRRRSSSSED----------ERR---------------------- 207

  Fly   261 AKYRTISNQLDMATKKKKSKKSKKKKSSDSSDESSDEEEEPRRKHKRSHSSEDRNQRERRRSRSP 325
             |:|:...:.|:.|             |:....|....:.|..:...|.:|...:.|.|.|||||
Zfish   208 -KHRSREEKSDVTT-------------SNGHHRSGYGLQLPAHRSTHSSASNHTDHRSRDRSRSP 258

  Fly   326 ----RDRKKRQSRSPEQRQRQRSPEERRERRRSRSRSPLARRQRRTRSPEDRKARRQSKDTSKQR 386
                .||....||..|::.:.::|...|.|                    ||..|.|..:.||
Zfish   259 LSHKADRDNHSSRESERKAKPKAPSPPRHR--------------------DRYQRPQYTNYSK-- 301

  Fly   387 EKRRSRTPEERSRSKRSRSRSSKGDDKRRIAERPPPSRPTGKPKLSEADREARLREMMDNATWRE 451
                                                       :||..:.|.:.|||||.|..||
Zfish   302 -------------------------------------------RLSAEELEKKRREMMDFARERE 323

  Fly   452 ADRSQVVRKHREAYAREEAQNRERDFDKE-----FINKEVKKAIANHNSIGDRIRANLNNIQRTA 511
            .:|...|::    |.|:|.|.:.|:..|:     ||: |:|...|..:|:.||::.|:::||||.
Zfish   324 VERENNVQR----YKRQEEQEKAREDAKQDRHAGFIH-EMKLESAATSSLEDRVKRNIHSIQRTP 383

  Fly   512 SSMDSNFARK 521
            ::::.||.|:
Zfish   384 AALEKNFMRR 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cwc25	NP_608705.1	Cir_N	11..44	CDD:462992	18/32 (56%)
		CWC25	74..175	CDD:463626	38/100 (38%)
cwc25	NP_998627.1	Cir_N	11..>37	CDD:462992	15/25 (60%)
		CWC25	67..157	CDD:463626	38/102 (37%)
		SF-CC1	245..>360	CDD:273721	43/184 (23%)