Protein Alignment Cwc25 and Cwc25

DIOPT Version :10

• Sequence 1: NP_608705.1
• Gene: Cwc25 / 33460
• FlyBaseID: FBgn0031452
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001101765.1
• Gene: Cwc25 / 360613
• RGDID: 1305258
• Length: 415
• Species: Rattus norvegicus
• Alignment Length: 528
• Identity: 164/528 - (31%)
• Similarity: 262/528 - (49%)
• Gaps: 120/528 - (22%)

  Fly     1 MGGGDLNLKKSWHPHTMKNQERVWKAEEQAKMEERKLQDLRKEINEERDREELRRLGESSGVLSN 65
            ||||||||||||||.|::|.|:|||||::.:.|.:|:::|::|:.|||.|||::|..|..|.:..
  Rat     1 MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKK 65

  Fly    66 NGGAAGEAKLEWMYKNSTELINREEYLLGRKIDK-SFETLQAEESRQEQNTVGLKQTINHVEHDC 129
            .     |.||:|||:....:::|:||||||.||| .||.::..|:.....| ||
  Rat    66 K-----EEKLDWMYQGPGGMVSRDEYLLGRPIDKYVFEKMEEREAGCSSET-GL----------- 113

  Fly   130 VPFSIRTYRNVQSNEQVDIQRKTLEDPLMLIKQREMESRRKLLENPVKLKEIHRILKTEQEQKAA 194
            :|.||  :....:|..:|:..|..||||.:|:::|.|.:|::|.||||:::|..:|:...|
  Rat   114 LPGSI--FAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMRKIKELLQMSLE---- 172

  Fly   195 EGKKKNKKNKKSKKSKKKKKNRRSSNEESSDSESNDSDDDLDRKLARQ---VSKLKGDQGDLKLD 256
               ||.||.||.||.|.:|...|||:.:.|.||...|.....:|:|..   :||:.|
  Rat   173 ---KKEKKKKKEKKKKHRKHKHRSSSSDRSSSEDEQSHGRSQKKMANSFPVLSKVPG-------- 226

  Fly   257 KLLDAKYRTISNQLDMATKKKKSKKSKKKKSSDSSD--ESSDEEEEPRRKHKRSHSSEDRNQRER 319
                                    ...:.:.||.:.  :.|..|:...:.|.||
  Rat   227 ------------------------YGLQVRDSDRNQGLQGSLGEQRAVKNHSRS----------- 256

  Fly   320 RRSRSPRDRKKRQSRSPEQRQRQRSPEERRERRRSRSRSPLARRQRRTRSPEDRKARRQSKDTSK 384
                         |.||.:...::|.:|.|.|.| |||||    .|::.||     |...:.|||
  Rat   257 -------------SSSPARHASRKSTKEERSRDR-RSRSP----GRKSLSP-----RPSKQHTSK 298

  Fly   385 -QREKRRSRTPEERSRSKRSRSRSSKGDDKRRIAERPPPSRPTGKPKLSEADREARLREMMDNAT 448
             .|::|.|.:|::....:|..|..::                    |||..:.|.:.:|||:||.
  Rat   299 ANRKERDSPSPKKEVYQRRHASGYTR--------------------KLSAEELERKRQEMMENAK 343

  Fly   449 WREADRSQVVRKHREAYAREEAQNRERDFDKEFINKEVKKAIANHNSIGDRIRANLNNIQRTASS 513
            |||.:|...:::|.:...:|....|......:||:: :|...|:.:|:.||::.|::::|||:.:
  Rat   344 WREEERLNTLKRHAKEDEQEHRLERLDSRSGKFIHR-MKLESASTSSLEDRVKRNIHSLQRTSMA 407

  Fly   514 MDSNFARK 521
            ::.||.|:
  Rat   408 LEKNFMRR 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cwc25	NP_608705.1	Cir_N	11..44	CDD:462992	15/32 (47%)
		CWC25	74..175	CDD:463626	36/101 (36%)
Cwc25	NP_001101765.1	Cir_N	11..>37	CDD:462992	13/25 (52%)
		CWC25	67..157	CDD:463626	30/90 (33%)