DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9961 and PGK1

DIOPT Version :9

Sequence 1:	NP_608704.2	Gene:	CG9961 / 33459	FlyBaseID:	FBgn0031451	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_009938.2	Gene:	PGK1 / 850370	SGDID:	S000000605	Length:	416	Species:	Saccharomyces cerevisiae

Alignment Length:	411	Identity:	233/411 - (56%)
Similarity:	310/411 - (75%)	Gaps:	2/411 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KLSLKNVDVAGKRVFMRVDFNVPMKDGKITNNQRIVSALPSIKYALDKKCKSLVLASHLGRPDGK 101
            |||::::|:..||||:|||||||:...|||:|||||:|||:|||.|:...:.:|||||||||:|:
Yeast     6 KLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGE 70

  Fly   102 KNKKFSLEPVAKELESVLGQPVQFLDDCVGDSTLRALKDPSDGTVFLLENLRFYAEETGSSKDDN 166
            :|:|:||.||||||:|:||:.|.||:||||.....|:|..:.|:|.||||||::.||.||.|.|.
Yeast    71 RNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKVDG 135

  Fly   167 KKKVKADPAKVKEFRAKLAQLGEIYVNDAFGTAHRPHSSMMGDGYKVRAAGFLLDKELEYFAKVL 231
             :||||....|::||.:|:.|.::|:|||||||||.||||:|.....|||||||:|||:||.|.|
Yeast   136 -QKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKAL 199

  Fly   232 HDPAKPFLAILGGAKIADKIPLITNLLNNVTAMIISGGMAFTFLKVLNGMEIGKSLFDEKGSELV 296
            .:|.:||||||||||:||||.||.|||:.|.::||.|||||||.|||...|||.|:||:.|:|:|
Yeast   200 ENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIGDSIFDKAGAEIV 264

  Fly   297 NDIVCKAKEKDVNILFPIDFVIANKIDKEPDKVEHVDATQGIPEDMMGLDHGQASSQMFAGAICA 361
            ..::.|||.|.|.::.|:||:||:....:.: .:.|...:|||....|||:|..|.::||..:..
Yeast   265 PKLMEKAKAKGVEVVLPVDFIIADAFSADAN-TKTVTDKEGIPAGWQGLDNGPESRKLFAATVAK 328

  Fly   362 SKTIVWNGPPGLFENELFSKGTESMLEAVIGATNRGATTIVGGGDTATACLKFGGADKVSHVSTG 426
            :||||||||||:||.|.|:.||:::|:.|:.::..|.|.|:|||||||...|:|..||:||||||
Yeast   329 AKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTG 393

  Fly   427 GGASLELLEGKVLPGVAALSD 447
            |||||||||||.|||||.||:
Yeast   394 GGASLELLEGKELPGVAFLSE 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9961	NP_608704.2	Phosphoglycerate_kinase	36..447	CDD:294132	232/409 (57%)
PGK1	NP_009938.2	Phosphoglycerate_kinase	3..415	CDD:412214	233/411 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343045
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S171
OMA	1	1.010	-	-		QHG60610
OrthoFinder	1	1.000	-	-		FOG0001721
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100440
Panther	1	1.100	-	-	O	PTHR11406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1109
TreeFam	1	0.960	-	-
	10	9.660