Protein Alignment CG9961 and PGK2

DIOPT Version :9

• Sequence 1: NP_608704.2
• Gene: CG9961 / 33459
• FlyBaseID: FBgn0031451
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_620061.2
• Gene: PGK2 / 5232
• HGNCID: 8898
• Length: 417
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 240/413 - (58%)
• Similarity: 310/413 - (75%)
• Gaps: 2/413 - (0%)

  Fly    36 KKLSLKNVDVAGKRVFMRVDFNVPMKDGKITNNQRIVSALPSIKYALDKKCKSLVLASHLGRPDG 100
            |||:|..:||.||||.||||||||||..:|||||||.:::|||||.||...|::||.||||||||
Human     5 KKLTLDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVLMSHLGRPDG 69

  Fly   101 -KKNKKFSLEPVAKELESVLGQPVQFLDDCVGDSTLRALKDPSDGTVFLLENLRFYAEETGSSKD 164
             ....|:||.|||.||:|:||:.|.||.||||....:|..:|:.|:|.|||||||:.||.|..:|
Human    70 VPMPDKYSLAPVAVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLENLRFHVEEEGKGQD 134

  Fly   165 DNKKKVKADPAKVKEFRAKLAQLGEIYVNDAFGTAHRPHSSMMGDGYKVRAAGFLLDKELEYFAK 229
            .:.||:||:|.|::.|||.|::||::|||||||||||.||||:|.....:|:|||:.|||:||||
Human   135 PSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPHKASGFLMKKELDYFAK 199

  Fly   230 VLHDPAKPFLAILGGAKIADKIPLITNLLNNVTAMIISGGMAFTFLKVLNGMEIGKSLFDEKGSE 294
            .|.:|.:||||||||||:||||.||.|:|:.|..|||.||||:|||||||.||||.|||||:|::
Human   200 ALENPVRPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGMAYTFLKVLNNMEIGASLFDEEGAK 264

  Fly   295 LVNDIVCKAKEKDVNILFPIDFVIANKIDKEPDKVEHVDATQGIPEDMMGLDHGQASSQMFAGAI 359
            :|.||:.||::..|.|.||:|||..:|.| |..:|.......||....||||.|..|::..|..:
Human   265 IVKDIMAKAQKNGVRITFPVDFVTGDKFD-ENAQVGKATVASGISPGWMGLDCGPESNKNHAQVV 328

  Fly   360 CASKTIVWNGPPGLFENELFSKGTESMLEAVIGATNRGATTIVGGGDTATACLKFGGADKVSHVS 424
            ..::.||||||.|:||.:.|:|||:::::.::.||::|..|::|||||||.|.|:...|||||||
Human   329 AQARLIVWNGPLGVFEWDAFAKGTKALMDEIVKATSKGCITVIGGGDTATCCAKWNTEDKVSHVS 393

  Fly   425 TGGGASLELLEGKVLPGVAALSD 447
            |||||||||||||:||||.|||:
Human   394 TGGGASLELLEGKILPGVEALSN 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9961	NP_608704.2	Phosphoglycerate_kinase	36..447	CDD:294132	239/411 (58%)
PGK2	NP_620061.2	PTZ00005	3..416	CDD:173310	239/411 (58%)
		Substrate binding. /evidence=ECO:0000250	24..26		1/1 (100%)
		Substrate binding. /evidence=ECO:0000250	63..66		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60610
OrthoDB	1	1.010	-	-		D367407at33208
OrthoFinder	1	1.000	-	-		FOG0001721
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100440
Panther	1	1.100	-	-	O	PTHR11406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.790