Protein Alignment CG9961 and PGK1

DIOPT Version :9

• Sequence 1: NP_608704.2
• Gene: CG9961 / 33459
• FlyBaseID: FBgn0031451
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_000282.1
• Gene: PGK1 / 5230
• HGNCID: 8896
• Length: 417
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 251/412 - (60%)
• Similarity: 310/412 - (75%)
• Gaps: 2/412 - (0%)

  Fly    37 KLSLKNVDVAGKRVFMRVDFNVPMKDGKITNNQRIVSALPSIKYALDKKCKSLVLASHLGRPDG- 100
            ||:|..:||.||||.||||||||||:.:|||||||.:|:||||:.||...||:||.||||||||
Human     6 KLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGV 70

  Fly   101 KKNKKFSLEPVAKELESVLGQPVQFLDDCVGDSTLRALKDPSDGTVFLLENLRFYAEETGSSKDD 165
            ....|:||||||.||:|:||:.|.||.||||....:|..:|:.|:|.|||||||:.||.|..||.
Human    71 PMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDA 135

  Fly   166 NKKKVKADPAKVKEFRAKLAQLGEIYVNDAFGTAHRPHSSMMGDGYKVRAAGFLLDKELEYFAKV 230
            :..||||:|||::.|||.|::||::|||||||||||.||||:|.....:|.|||:.|||.||||.
Human   136 SGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKA 200

  Fly   231 LHDPAKPFLAILGGAKIADKIPLITNLLNNVTAMIISGGMAFTFLKVLNGMEIGKSLFDEKGSEL 295
            |..|.:||||||||||:||||.||.|:|:.|..|||.||||||||||||.||||.|||||:|:::
Human   201 LESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKI 265

  Fly   296 VNDIVCKAKEKDVNILFPIDFVIANKIDKEPDKVEHVDATQGIPEDMMGLDHGQASSQMFAGAIC 360
            |.|::.||::..|.|..|:|||.|:|.| |..|........|||...||||.|..||:.:|.|:.
Human   266 VKDLMSKAEKNGVKITLPVDFVTADKFD-ENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVT 329

  Fly   361 ASKTIVWNGPPGLFENELFSKGTESMLEAVIGATNRGATTIVGGGDTATACLKFGGADKVSHVST 425
            .:|.||||||.|:||.|.|::||:::::.|:.||:||..||:|||||||.|.|:...||||||||
Human   330 RAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVST 394

  Fly   426 GGGASLELLEGKVLPGVAALSD 447
            |||||||||||||||||.|||:
Human   395 GGGASLELLEGKVLPGVDALSN 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9961	NP_608704.2	Phosphoglycerate_kinase	36..447	CDD:294132	250/410 (61%)
PGK1	NP_000282.1	PTZ00005	3..417	CDD:173310	251/412 (61%)
		Substrate binding. /evidence=ECO:0000269|PubMed:18463139	24..26		1/1 (100%)
		Substrate binding. /evidence=ECO:0000269|PubMed:18463139	63..66		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60610
OrthoDB	1	1.010	-	-		D367407at33208
OrthoFinder	1	1.000	-	-		FOG0001721
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100440
Panther	1	1.100	-	-	O	PTHR11406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.790