DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9961 and Pgk

DIOPT Version :9

Sequence 1:	NP_608704.2	Gene:	CG9961 / 33459	FlyBaseID:	FBgn0031451	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_001259956.1	Gene:	Pgk / 33461	FlyBaseID:	FBgn0250906	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	412	Identity:	258/412 - (62%)
Similarity:	314/412 - (76%)	Gaps:	1/412 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KLSLKNVDVAGKRVFMRVDFNVPMKDGKITNNQRIVSALPSIKYALDKKCKSLVLASHLGRPDGK 101
            |||::|:|:|||||.||||||||:|:||||:|||||:||.|||.||.||.||:||.||||||||.
  Fly     5 KLSIENLDLAGKRVLMRVDFNVPIKEGKITSNQRIVAALDSIKLALSKKAKSVVLMSHLGRPDGN 69

  Fly   102 KNKKFSLEPVAKELESVLGQPVQFLDDCVGDSTLRALKDPSDGTVFLLENLRFYAEETGSSKDDN 166
            ||.|::|.|||.||:::|||.|.||.||||.....|.|||:.|:|.||||:|||.||.|...|.:
  Fly    70 KNIKYTLAPVAAELKTLLGQDVIFLSDCVGSEVEAACKDPAPGSVILLENVRFYVEEEGKGLDAS 134

  Fly   167 KKKVKADPAKVKEFRAKLAQLGEIYVNDAFGTAHRPHSSMMGDGYKVRAAGFLLDKELEYFAKVL 231
            ..||||||||||||||.||:||::|||||||||||.||||||||::.||||.||:|||:||::.|
  Fly   135 GGKVKADPAKVKEFRASLAKLGDVYVNDAFGTAHRAHSSMMGDGFEQRAAGLLLNKELKYFSQAL 199

  Fly   232 HDPAKPFLAILGGAKIADKIPLITNLLNNVTAMIISGGMAFTFLKVLNGMEIGKSLFDEKGSELV 296
            ..|..||||||||||:||||.||.|||:.|..|||.||||||||||||.|:||.|||||:||::|
  Fly   200 DKPPNPFLAILGGAKVADKIQLIENLLDKVNEMIIGGGMAFTFLKVLNNMKIGGSLFDEEGSKIV 264

  Fly   297 NDIVCKAKEKDVNILFPIDFVIANKIDKEPDKVEHVDATQGIPEDMMGLDHGQASSQMFAGAICA 361
            ..:|.|||:.:|.:..|:|||..:|. .|...|.......|||:..||||.|..:.::||..|..
  Fly   265 EKLVEKAKKNNVQLHLPVDFVCGDKF-AENAAVSEATVEAGIPDGHMGLDVGPKTRELFAAPIAR 328

  Fly   362 SKTIVWNGPPGLFENELFSKGTESMLEAVIGATNRGATTIVGGGDTATACLKFGGADKVSHVSTG 426
            :|.||||||||:||...|:.||:|:::.|:.||..|..:|:||||||:.|.|:.....|||||||
  Fly   329 AKLIVWNGPPGVFEFPNFANGTKSIMDGVVAATKNGTVSIIGGGDTASCCAKWNTEALVSHVSTG 393

  Fly   427 GGASLELLEGKVLPGVAALSDA 448
            |||||||||||.|||||||:.|
  Fly   394 GGASLELLEGKTLPGVAALTSA 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9961	NP_608704.2	Phosphoglycerate_kinase	36..447	CDD:294132	257/409 (63%)
Pgk	NP_001259956.1	Phosphoglycerate_kinase	1..414	CDD:294132	257/409 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445023
Domainoid	1	1.000	320	1.000	Domainoid score	I280
eggNOG	1	0.900	-	-		E1_COG0126
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	333	1.000	Inparanoid score	I671
Isobase	1	0.950	-	0	Normalized mean entropy	S171
OMA	1	1.010	-	-		QHG60610
OrthoDB	1	1.010	-	-		D367407at33208
OrthoFinder	1	1.000	-	-		FOG0001721
OrthoInspector	1	1.000	-	-		otm51431
orthoMCL	1	0.900	-	-		OOG6_100440
Panther	1	1.100	-	-	P	PTHR11406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1109
	13	12.760