DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9961 and pgk1

DIOPT Version :9

Sequence 1:	NP_608704.2	Gene:	CG9961 / 33459	FlyBaseID:	FBgn0031451	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_596730.1	Gene:	pgk1 / 2539764	PomBaseID:	SPBC14F5.04c	Length:	414	Species:	Schizosaccharomyces pombe

Alignment Length:	410	Identity:	246/410 - (60%)
Similarity:	305/410 - (74%)	Gaps:	3/410 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KLSLKNVDVAGKRVFMRVDFNVPMKDGKITNNQRIVSALPSIKYALDKKCKSLVLASHLGRPDGK 101
            ||::.:||:.||.|.:|||||||:...:||||.|||.|||:|||||:::.|:::|.||||||:|.
pombe     6 KLAITDVDLKGKNVLIRVDFNVPLDGDRITNNARIVGALPTIKYALEQQPKAVILMSHLGRPNGA 70

  Fly   102 KNKKFSLEPVAKELESVLGQPVQFLDDCVGDSTLRALKDPSDGTVFLLENLRFYAEETGSSKDDN 166
            :..|:||:|||.||..:||:||:|||||||....:|.|:...|.|.|||||||:.||.||:|.|.
pombe    71 RVAKYSLKPVAAELSKLLGKPVKFLDDCVGPEVEKACKEAKGGEVILLENLRFHIEEEGSAKVDG 135

  Fly   167 KKKVKADPAKVKEFRAKLAQLGEIYVNDAFGTAHRPHSSMMGDGYKVRAAGFLLDKELEYFAKVL 231
             ||||||.:.|:.||..|..||:|:||||||||||.||||:|.... |.:|||:.|||:||:|.|
pombe   136 -KKVKADASAVEAFRKSLTSLGDIFVNDAFGTAHRAHSSMVGVDLP-RVSGFLMKKELDYFSKAL 198

  Fly   232 HDPAKPFLAILGGAKIADKIPLITNLLNNVTAMIISGGMAFTFLKVLNGMEIGKSLFDEKGSELV 296
            .:||:||||||||||:||||.||.|||:.|..:||.||||||||||||||:||.|||||.||:.|
pombe   199 ENPARPFLAILGGAKVADKIQLIDNLLDKVNRLIICGGMAFTFLKVLNGMKIGDSLFDEAGSKNV 263

  Fly   297 NDIVCKAKEKDVNILFPIDFVIANKIDKEPDKVEHVDATQGIPEDMMGLDHGQASSQMFAGAICA 361
            ..::.|||:.:|.:..|:|||.|:|.||:. ||....|.:|||:..||||.|..||..||..|..
pombe   264 ESMMAKAKKNNVEVFLPVDFVTADKFDKDA-KVGSATAEEGIPDGWMGLDCGPKSSAKFAEVITT 327

  Fly   362 SKTIVWNGPPGLFENELFSKGTESMLEAVIGATNRGATTIVGGGDTATACLKFGGADKVSHVSTG 426
            |||||||||.|:||.:.|:|||:|||:|.:.....|...|||||||||...|:|..|.:||||||
pombe   328 SKTIVWNGPAGVFEFDNFAKGTKSMLDACVKTCEAGNVVIVGGGDTATVAKKYGKEDALSHVSTG 392

  Fly   427 GGASLELLEGKVLPGVAALS 446
            |||||||||||.||||.|||
pombe   393 GGASLELLEGKALPGVVALS 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9961	NP_608704.2	Phosphoglycerate_kinase	36..447	CDD:294132	246/410 (60%)
pgk1	NP_596730.1	PTZ00005	3..414	CDD:173310	246/410 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60610
OrthoFinder	1	1.000	-	-		FOG0001721
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100440
Panther	1	1.100	-	-	O	PTHR11406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1109
TreeFam	1	0.960	-	-
	8	7.780