Protein Alignment CG9961 and Pgk1

DIOPT Version :10

• Sequence 1: NP_608704.2
• Gene: CG9961 / 33459
• FlyBaseID: FBgn0031451
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_032854.2
• Gene: Pgk1 / 18655
• MGIID: 97555
• Length: 417
• Species: Mus musculus
• Alignment Length: 412
• Identity: 252/412 - (61%)
• Similarity: 308/412 - (74%)
• Gaps: 2/412 - (0%)

  Fly    37 KLSLKNVDVAGKRVFMRVDFNVPMKDGKITNNQRIVSALPSIKYALDKKCKSLVLASHLGRPDG- 100
            ||:|..:||.||||.||||||||||:.:|||||||.:|:||||:.||...||:||.||||||||
Mouse     6 KLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGV 70

  Fly   101 KKNKKFSLEPVAKELESVLGQPVQFLDDCVGDSTLRALKDPSDGTVFLLENLRFYAEETGSSKDD 165
            ....|:||||||.||:|:||:.|.||.||||.....|..:|:.|||.|||||||:.||.|..||.
Mouse    71 PMPDKYSLEPVAAELKSLLGKDVLFLKDCVGPEVENACANPAAGTVILLENLRFHVEEEGKGKDA 135

  Fly   166 NKKKVKADPAKVKEFRAKLAQLGEIYVNDAFGTAHRPHSSMMGDGYKVRAAGFLLDKELEYFAKV 230
            :..||||:|||:..|||.|::||::|||||||||||.||||:|.....:|.|||:.|||.||||.
Mouse   136 SGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKA 200

  Fly   231 LHDPAKPFLAILGGAKIADKIPLITNLLNNVTAMIISGGMAFTFLKVLNGMEIGKSLFDEKGSEL 295
            |..|.:||||||||||:||||.||.|:|:.|..|||.||||||||||||.||||.||:||:|:::
Mouse   201 LESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLYDEEGAKI 265

  Fly   296 VNDIVCKAKEKDVNILFPIDFVIANKIDKEPDKVEHVDATQGIPEDMMGLDHGQASSQMFAGAIC 360
            |.|::.||::..|.|..|:|||.|:|.| |..|........|||...||||.|..||:.:|.|:.
Mouse   266 VKDLMSKAEKNGVKITLPVDFVTADKFD-ENAKTGQATVASGIPAGWMGLDCGTESSKKYAEAVG 329

  Fly   361 ASKTIVWNGPPGLFENELFSKGTESMLEAVIGATNRGATTIVGGGDTATACLKFGGADKVSHVST 425
            .:|.||||||.|:||.|.|::||:|:::.|:.||:||..||:|||||||.|.|:...||||||||
Mouse   330 RAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVST 394

  Fly   426 GGGASLELLEGKVLPGVAALSD 447
            |||||||||||||||||.|||:
Mouse   395 GGGASLELLEGKVLPGVDALSN 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9961	NP_608704.2	Phosphoglycerate_kinase	36..447	CDD:444741	251/410 (61%)
Pgk1	NP_032854.2	PTZ00005	3..416	CDD:173310	251/410 (61%)
		Mitochondrial targeting region exposed following cis-trans isomerization by PIN1 and recognized by the TOM complex for mitochondrial translocation of the protein. /evidence=ECO:0000250|UniProtKB:P00558	38..43		3/4 (75%)